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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes.
Viral evolution and challenges in the development of HIV vaccines.
Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination.
Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys.
Novel replication-incompetent adenoviral B-group vectors: high vector stability and yield in PER.C6 cells.
Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination.
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates.
Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity.
Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys.
Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens.
Immunologic strategies for HIV-1 remission and eradication.
Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.
Attenuation of Replication-Competent Adenovirus Serotype 26 Vaccines by Vectorization.
Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys.
First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1.
SARS-CoV-2 infection protects against rechallenge in rhesus macaques.