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One or more keywords matched the following items that are connected to Martuza, Robert
Item TypeName
Academic Article Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: a light and electron microscopic study.
Academic Article Expression of L1 in primary astrocytes via a defective herpes simplex virus vector promotes neurite outgrowth and neural cell migration.
Academic Article In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity.
Academic Article Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates.
Academic Article Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain.
Academic Article Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity.
Academic Article Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system.
Academic Article Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma.
Academic Article Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice.
Academic Article Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial.
Academic Article Oncolytic herpes simplex virus therapy for peripheral nerve tumors.
Academic Article Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses.
Academic Article Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase.
Academic Article Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer.
Academic Article Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1.
Academic Article Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells.
Academic Article Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207.
Academic Article Clinical mutations in the L1 neural cell adhesion molecule affect cell-surface expression.
Academic Article Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
Academic Article Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases.
Academic Article Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector.
Academic Article Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors.
Academic Article Hypoxia enhances the replication of oncolytic herpes simplex virus.
Academic Article Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.
Academic Article Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing.
Academic Article Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer.
Academic Article Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers.
Academic Article [Gene therapy for brain tumors: experimental treatment of malignant brain tumors using recombinant herpes simplex virus type 1 (series 7)].
Academic Article Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant.
Academic Article Expanded spectrum of viral therapy in the treatment of nervous system tumors.
Academic Article Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus.
Academic Article Analysis of genetically engineered oncolytic herpes simplex viruses in human prostate cancer organotypic cultures.
Academic Article Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor.
Academic Article Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model.
Academic Article Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma.
Academic Article Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma.
Academic Article Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine.
Academic Article Experimental therapy of human glioma by means of a genetically engineered virus mutant.
Academic Article Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene.
Academic Article Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication.
Academic Article Molecular neurosurgery for glial and neuronal disorders.
Academic Article Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
Academic Article Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir.
Academic Article An experimental model of retrovirus gene therapy for malignant brain tumors.
Academic Article Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells.
Academic Article Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects.
Academic Article Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors.
Academic Article Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus.
Academic Article Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models.
Academic Article Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy.
Academic Article Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors.
Academic Article In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity.
Academic Article Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo.
Academic Article CNS tumor therapy by attenuated herpes simplex viruses.
Academic Article Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma.
Academic Article Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy.
Academic Article Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics.
Academic Article Effect of ?34.5 deletions on oncolytic herpes simplex virus activity in brain tumors.
Academic Article Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.
Academic Article Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.
Academic Article Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells.
Academic Article Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells.
Academic Article A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells.
Academic Article Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
Academic Article Defective herpes simplex virus vectors for the study of promoter and gene function in the CNS.
Academic Article Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts.
Academic Article Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation.
Academic Article Transcriptional targeting of herpes simplex virus for cell-specific replication.
Academic Article Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice.
Academic Article Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates.
Academic Article Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide.
Academic Article Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta.
Academic Article Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas.
Concept Simplexvirus
Academic Article Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model.
Academic Article Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models.
Academic Article Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus.
Academic Article Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma.
Academic Article A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.
Grant Genetically Engineered Viruses for Brain Tumor Therapy
Grant Genetically Engineered Viruses for Prostate Cancer Therapy
Academic Article 840 Enhanced Replication of Oncolytic Herpes Simplex Virus in Glioma Cells that Evade Temozolomide Chemotherapy through DNA Repair.
Academic Article Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma.
Academic Article Blockade of transforming growth factor-ß signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models.
Academic Article Restriction of Replication of Oncolytic Herpes Simplex Virus with a Deletion of ?34.5 in Glioblastoma Stem-Like Cells.
Academic Article Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma.
Academic Article Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells.
Search Criteria
  • Simplexvirus
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.