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One or more keywords matched the following properties of Giovannucci, Edward
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overview My primary research efforts focus on how nutritional, hormonal, and genetic factors are related to various malignancies, especially those of the prostate and large bowel. Much of this work is based on the Nurses' Health Study, the Health Professionals Follow-Up Study and the Physicians' Health Study cohorts. For prostate cancer, my work has centered on the role of specific antioxidants, particularly lycopene, and on the potentially deleterious effects of diets high in calcium and dietary fat. In addition to establishing risk factors, we have been interested in understanding etiologic mechanisms that will help provide a solid scientific rationale for preventive strategies. Specifically, I have studied how nutritional factors influence prostate cancer through modulating levels of insulin-like growth factors (IGFs) and binding proteins, insulin, vitamin D metabolites, and steroid hormones. More recently, our work has examined the role of obesity and energy balance in the progression of prostate cancer. Regarding colorectal cancer, our work in the Nurses' Health Study and Health Professionals Follow-Up Study has established specific modifiable risk factors that contribute to over 70% of colorectal cancers. We have helped establish several factors that increase risk of colorectal cancer, including central obesity, physical inactivity, smoking, and diets high in red and processed meats. We have also hypothesized and demonstrated that some of these factors increase risk through higher insulin and IGF levels. We have also identified potential protective micronutrients, including vitamin D, folate, calcium and vitamin B6. We are testing the efficacy of some of these potentially protective agents, including folic acid, vitamin D, and vitamin B6 in randomized intervention trials. Finally, we have undertaken the collection of tumor tissue blocks for prostate cancer and colorectal cancer and precursor lesions (adenomas) within the Nurses' Health Study, Physicians' Health Study, and Health Professionals Follow-Up Study. With these specimens, we are identifying specific somatic molecular alterations in tumors. These alterations have been shown to have powerful influences on survival. We are now linking specific nutritional and lifestyle exposures to the probability of possessing certain of these tissue markers among those who develop cancer. Ultimately, we plan to provide the most comprehensive examination of the relations of dietary and other modifiable factors, hormonal factors, genetic susceptibility, and specific molecular endpoints in tumors. The great strength of our unique approach is to have updated and integrated data on all these factors, over up to a 30 year time period. My research work is mostly funded through the National Institutes of Health (R01's, R21's, R03's, P01), all from the National Cancer Institute. I also have funding from the American Institute of Cancer Research. My major teaching effort has been as an instructor in two courses, Cancer Epidemiology and Nutritional Epidemiology of Cancer at the Harvard School of Public Health. I do not have clinical duties.
One or more keywords matched the following items that are connected to Giovannucci, Edward
Item TypeName
Academic Article How is individual risk for prostate cancer assessed?
Academic Article Physical activity, obesity, and risk of colorectal adenoma in women (United States).
Academic Article Calcium, vitamin D, and the occurrence of colorectal cancer among women.
Academic Article A prospective study of cigarette smoking and the risk of pancreatic cancer.
Academic Article A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.
Academic Article A prospective study of reproductive factors, oral contraceptive use, and risk of colorectal cancer.
Academic Article A prospective study of dietary fiber types and symptomatic diverticular disease in men.
Academic Article Selenium and risk of prostate cancer.
Academic Article What causes prostate cancer? A brief summary of the epidemiology.
Academic Article RESPONSE: Re: Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3.
Academic Article Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men.
Academic Article Insulin, insulin-like growth factors and colon cancer: a review of the evidence.
Academic Article ATAAA repeat upstream of glutathione S-transferase P1 and prostate cancer risk.
Academic Article Prevalence and correlates of prostatitis in the health professionals follow-up study cohort.
Academic Article Fruits, vegetables and lung cancer: a pooled analysis of cohort studies.
Academic Article Dietary carbohydrates and glycaemic load and the incidence of symptomatic gall stone disease in men.
Academic Article Tomato products, lycopene, and prostate cancer: a review of the epidemiological literature.
Academic Article Dietary iron, zinc, and calcium and the risk of lung cancer.
Academic Article The assessment of alcohol consumption by a simple self-administered questionnaire.
Academic Article Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes.
Academic Article Intake of potassium, magnesium, calcium, and fiber and risk of stroke among US men.
Academic Article A prospective study of physical activity and prostate cancer in male health professionals.
Academic Article Risk factors for basal cell carcinoma of the skin in men: results from the health professionals follow-up study.
Academic Article Racial variation in insulin-like growth factor-1 and binding protein-3 concentrations in middle-aged men.
Academic Article A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women.
Academic Article Blood donations and risk of coronary heart disease in men.
Academic Article Dietary fat and cancer.
Academic Article Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence.
Academic Article A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma.
Academic Article Fiber from fruit and colorectal neoplasia.
Academic Article Polymorphism in the thymidylate synthase promoter enhancer region and risk of colorectal adenomas.
Academic Article A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women.
Academic Article A prospective study of social networks in relation to total mortality and cardiovascular disease in men in the USA.
Academic Article The role of fat, fatty acids, and total energy intake in the etiology of human colon cancer.
Academic Article Parity and other reproductive factors and risk of adenomatous polyps of the distal colorectum (United States).
Academic Article Use of acetaminophen and nonsteroidal anti-inflammatory drugs: a prospective study and the risk of symptomatic diverticular disease in men.
Academic Article High rates of prostate-specific antigen testing in men with evidence of benign prostatic hyperplasia.
Academic Article A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma.
Academic Article A prospective study of folate intake and the risk of breast cancer.
Academic Article Toenail selenium concentrations and bladder cancer risk in women and men.
Academic Article Recreational physical activity and the risk of cholecystectomy in women.
Academic Article A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women.
Academic Article Family history as a risk factor for ulcerative colitis-associated colon cancer in cotton-top tamarin.
Academic Article Genetic variation in the HSD17B1 gene and risk of prostate cancer.
Academic Article Fruit and vegetable consumption and risk of cholecystectomy in women.
Academic Article Dietary carbohydrate, glycemic index, and glycemic load in relation to risk of colorectal cancer in women.
Academic Article Dietary mutagens and the risk of breast cancer.
Academic Article The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer.
Academic Article Adiposity and mortality in men.
Academic Article Intakes of energy and macronutrients and the risk of benign prostatic hyperplasia.
Academic Article A common 8q24 variant in prostate and breast cancer from a large nested case-control study.
Academic Article A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer.
Academic Article Epidemiological evidence for vitamin D and colorectal cancer.
Academic Article Effects of sample attrition in a longitudinal study of the association between alcohol intake and all-cause mortality.
Academic Article Obesity increases the risks of diverticulitis and diverticular bleeding.
Academic Article Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer.
Academic Article Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer.
Academic Article Coffee intake is associated with lower risk of symptomatic gallstone disease in women.
Academic Article Prostate cancer association studies: pitfalls and solutions to cancer misclassification in the PSA era.
Academic Article Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer.
Academic Article Diet and cancer prevention.
Academic Article Dietary marine n-3 fatty acids in relation to risk of distal colorectal adenoma in women.
Academic Article Fiber intake and incidence of colorectal cancer among 76,947 women and 47,279 men.
Academic Article Vitamin B6 intake, alcohol consumption, and colorectal cancer: a longitudinal population-based cohort of women.
Academic Article Associations of plasma carotenoid concentrations and dietary intake of specific carotenoids in samples of two prospective cohort studies using a new carotenoid database.
Academic Article Gamma-tocopherol: a new player in prostate cancer prevention?
Academic Article A long-term study of mortality in men who have undergone vasectomy.
Academic Article Vegetables, fruits, associated micronutrients, and risk of prostate cancer.
Academic Article Dairy products, calcium, and vitamin D and risk of prostate cancer.
Academic Article Tomato products, lycopene, and prostate cancer risk.
Academic Article Risk of cancer after growth-hormone treatment.
Academic Article Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance.
Academic Article Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women.
Academic Article A prospective study of plasma C-peptide and colorectal cancer risk in men.
Academic Article APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenoma.
Academic Article Long-term intake of trans-fatty acids and risk of gallstone disease in men.
Academic Article The epidemiology of vitamin D and colorectal cancer: recent findings.
Academic Article A prospective study of calcium intake and incident and fatal prostate cancer.
Academic Article Leisure-time physical activity patterns and risk of colon cancer in women.
Academic Article The impact of different therapies on symptoms of benign prostatic hyperplasia: a prospective study.
Academic Article A prospective study of alcohol, smoking, caffeine, and the risk of duodenal ulcer in men.
Academic Article Parity, reproductive factors, and the risk of pancreatic cancer in women.
Academic Article Racial variation in prostate cancer incidence and in hormonal system markers among male health professionals.
Academic Article The relationship between a polymorphism in CYP17 with plasma hormone levels and prostate cancer.
Academic Article Association of type and duration of diabetes with erectile dysfunction in a large cohort of men.
Academic Article Prospective study of diet and the risk of duodenal ulcer in men.
Academic Article Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study.
Academic Article Major dietary patterns and the risk of colorectal cancer in women.
Academic Article Failure to detect prostate cancer in the PSA era: comments on N Engl J Med 2003; 349: 215-224 and N Engl J Med 2003; 349: 335-342.
Academic Article Association between markers of the metabolic syndrome and lower urinary tract symptoms in the Third National Health and Nutrition Examination Survey (NHANES III).
Academic Article Adherence to the Dietary Guidelines for Americans and risk of major chronic disease in men.
Academic Article The influence of folate and multivitamin use on the familial risk of colon cancer in women.
Academic Article Dairy products, calcium, and prostate cancer risk in the Physicians' Health Study.
Academic Article Alcohol-folate interactions in the risk of oral cancer in women: a prospective cohort study.
Academic Article Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: results from the pancreatic cancer cohort consortium.
Academic Article Vitamin D receptor protein expression in tumor tissue and prostate cancer progression.
Academic Article Genome-wide association study identifies new prostate cancer susceptibility loci.
Academic Article Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with ß-catenin (CTNNB1) status.
Academic Article Obesity, gender, and colon cancer.
Academic Article Vitamin D and prevention of breast cancer: pooled analysis.
Academic Article Risk factors for prostate cancer incidence and progression in the health professionals follow-up study.
Academic Article Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studies.
Academic Article Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals.
Academic Article A prospective study of tomato products, lycopene, and prostate cancer risk.
Academic Article Calcium and fructose intake in relation to risk of prostate cancer.
Academic Article Distinction between symptoms of voiding and filling in benign prostatic hyperplasia: findings from the Health Professionals Follow-up Study.
Academic Article Vitamin D receptor polymorphisms, circulating vitamin D metabolites, and risk of prostate cancer in United States physicians.
Academic Article MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.
Academic Article Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer (Sweden)
Academic Article A prospective study of carotenoid intake and risk of cataract extraction in US men.
Academic Article Supplemental vitamin E intake and prostate cancer risk in a large cohort of men in the United States.
Academic Article Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study.
Academic Article The impact of cancer treatment on quality of life outcomes for patients with localized prostate cancer.
Academic Article Dietary fat and risk of lung cancer in a pooled analysis of prospective studies.
Academic Article Dinucleotide repeat in the insulin-like growth factor-I gene is not related to risk of colorectal adenoma.
Academic Article Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin.
Academic Article Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.
Academic Article A prospective study of aspirin use and the risk for colorectal adenoma.
Academic Article A prospective study of plasma selenium levels and prostate cancer risk.
Academic Article Long-term intake of dietary fiber and decreased risk of cholecystectomy in women.
Academic Article Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
Academic Article Folate intake and stomach cancer incidence in a prospective cohort of Swedish women.
Academic Article Dietary fiber and the risk of colorectal cancer and adenoma in women.
Academic Article Dietary influences of 1,25(OH)2 vitamin D in relation to prostate cancer: a hypothesis.
Academic Article Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3.
Academic Article Coffee and alcohol consumption and the risk of pancreatic cancer in two prospective United States cohorts.
Academic Article Epidemiologic studies of folate and colorectal neoplasia: a review.
Academic Article Modifiable risk factors for colon cancer.
Academic Article Dietary fiber and distal colorectal adenoma in men.
Academic Article Vasectomy and prostate cancer: a case-control study in India.
Academic Article Retrospective analysis of birth weight and prostate cancer in the Health Professionals Follow-up Study.
Academic Article A review of epidemiologic studies of tomatoes, lycopene, and prostate cancer.
Academic Article Nut, corn, and popcorn consumption and the incidence of diverticular disease.
Academic Article Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.
Academic Article Plasma steroid hormones, surgery for benign prostatic hyperplasia, and severe lower urinary tract symptoms.
Academic Article Intakes of fruit, vegetables, and carotenoids and renal cell cancer risk: a pooled analysis of 13 prospective studies.
Academic Article A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Academic Article Vitamin D and cardiovascular disease.
Academic Article Family history of cancer and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan).
Academic Article Vitamin D status of HIV-infected women and its association with HIV disease progression, anemia, and mortality.
Academic Article Primary prevention of colorectal cancer.
Academic Article ABO blood group and risk of colorectal cancer.
Academic Article Dietary sugar, glycemic load, and pancreatic cancer risk in a prospective study.
Academic Article Vitamin D, how much is enough and how much is too much?
Academic Article Associations of obesity with lower urinary tract symptoms and noncancer prostate surgery in the Third National Health and Nutrition Examination Survey.
Academic Article XRCC2 and XRCC3 polymorphisms are not associated with risk of colorectal adenoma.
Academic Article A prospective study of dietary folate intake and risk of colorectal cancer: modification by caffeine intake and cigarette smoking.
Academic Article Thiazide diuretics and the risk of gallbladder disease requiring surgery in women.
Academic Article The effect of long-term intake of cis unsaturated fats on the risk for gallstone disease in men: a prospective cohort study.
Academic Article A prospective cohort study of nut consumption and the risk of gallstone disease in men.
Academic Article Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era.
Academic Article Vitamin D and prevention of colorectal cancer.
Academic Article Fruit and vegetable consumption and colorectal adenomas in the Nurses' Health Study.
Academic Article A prospective study of nutritional factors and hypertension among US men.
Academic Article Diabetes mellitus and risk of prostate cancer (United States).
Academic Article Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature.
Academic Article Prospective study of body mass index, height, physical activity and incidence of bladder cancer in US men and women.
Academic Article Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk.
Academic Article Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study.
Academic Article Dietary choline and betaine and the risk of distal colorectal adenoma in women.
Academic Article Hormonal profile of diabetic men and the potential link to prostate cancer.
Academic Article CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Academic Article Zinc supplement use and risk of prostate cancer.
Academic Article Nutrition, insulin, insulin-like growth factors and cancer.
Academic Article A prospective study of aspirin use and the risk of pancreatic cancer in women.
Academic Article Alcohol, one-carbon metabolism, and colorectal cancer: recent insights from molecular studies.
Academic Article Cataract extraction and risk of breast cancer.
Academic Article Dietary glycemic load, carbohydrate, sugar, and colorectal cancer risk in men and women.
Academic Article Weight cycling and risk of gallstone disease in men.
Academic Article Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.
Academic Article Alcohol intake and colorectal cancer: a comparison of approaches for including repeated measures of alcohol consumption.
Academic Article Effectiveness of various mailing strategies among nonrespondents in a prospective cohort study.
Academic Article Ejaculation frequency and subsequent risk of prostate cancer.
Academic Article Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.
Academic Article Heme and non-heme iron consumption and risk of gallstone disease in men.
Academic Article Physical activity and benign prostatic hyperplasia.
Academic Article Common variants of FUT2 are associated with plasma vitamin B12 levels.
Academic Article Commentary. On the epidemiology of influenza: reply to Radonovich et al.
Academic Article Family history of prostate and breast cancer and the risk of prostate cancer in the PSA era.
Academic Article Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression.
Academic Article Vitamin D and prevention of colorectal adenoma: a meta-analysis.
Academic Article Prevalence and correlates of vitamin D status in African American men.
Academic Article Changes in plasma and oral mucosal lycopene isomer concentrations in healthy adults consuming standard servings of processed tomato products.
Academic Article Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancer.
Academic Article Physical activity, obesity, and risk for colon cancer and adenoma in men.
Academic Article DNA methylation, field effects, and colorectal cancer.
Academic Article Coffee consumption and incidence of colorectal cancer in two prospective cohort studies of Swedish women and men.
Academic Article Intake of folate and related nutrients in relation to risk of epithelial ovarian cancer.
Academic Article C-peptide, insulin-like growth factor binding protein-1, glycosylated hemoglobin, and the risk of distal colorectal adenoma in women.
Academic Article Flavonoid intake and colorectal cancer risk in men and women.
Academic Article Meat intake and bladder cancer risk in 2 prospective cohort studies.
Academic Article Gonorrhoea and male bladder cancer in a prospective study.
Academic Article Serum sex steroid hormones and lower urinary tract symptoms in Third National Health and Nutrition Examination Survey (NHANES III).
Academic Article Long-term effect of magnesium consumption on the risk of symptomatic gallstone disease among men.
Academic Article A prospective study of lower urinary tract symptoms and erectile dysfunction.
Academic Article Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer.
Academic Article Dietary carotenoids and the risk of invasive breast cancer.
Academic Article Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: vitamin A as an example.
Academic Article Expanding roles of vitamin D.
Academic Article A quantitative analysis of body mass index and colorectal cancer: findings from 56 observational studies.
Academic Article Prospective study of prostate tumor angiogenesis and cancer-specific mortality in the health professionals follow-up study.
Academic Article PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3).
Academic Article Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer.
Academic Article Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania.
Academic Article A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in U.S. men.
Academic Article O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States).
Academic Article Vitamin D intake and the risk for pancreatic cancer in two cohort studies.
Academic Article Tobacco, colorectal cancer, and adenomas: a review of the evidence.
Academic Article Characterization of gene-environment interactions for colorectal cancer susceptibility loci.
Academic Article Predictors of dietary heterocyclic amine intake in three prospective cohorts.
Academic Article The CAG repeat within the androgen receptor gene and benign prostatic hyperplasia.
Academic Article Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort.
Academic Article The V89L polymorphism in the 5alpha-reductase type 2 gene and risk of prostate cancer.
Academic Article Prospective study of vitamins C, E, and A and carotenoids and risk of oral premalignant lesions in men.
Academic Article Hormone replacement therapy and survival after colorectal cancer diagnosis.
Academic Article Statin drugs and risk of advanced prostate cancer.
Academic Article The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas.
Academic Article Circulating insulin-like growth factor binding protein-1 and the risk of pancreatic cancer.
Academic Article Can vitamin D reduce total mortality?
Academic Article Periodontal disease, tooth loss, and cancer risk in male health professionals: a prospective cohort study.
Academic Article Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies.
Academic Article Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.
Academic Article Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility.
Academic Article Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Academic Article A prospective study of magnesium and iron intake and pancreatic cancer in men.
Academic Article Dietary, but not supplemental, intakes of carotenoids and vitamin C are associated with decreased odds of lower urinary tract symptoms in men.
Academic Article Smoking and Barrett's esophagus in women who undergo upper endoscopy.
Academic Article Seasonal variation in expression of markers in the vitamin D pathway in prostate tissue.
Academic Article How many molecular subtypes? Implications of the unique tumor principle in personalized medicine.
Academic Article Dietary macronutrient and energy intake and urinary incontinence in women.
Academic Article Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan).
Academic Article The Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diets and colorectal cancer.
Academic Article Dietary acrylamide and risk of prostate cancer.
Academic Article Sun exposure and vitamin D are independent risk factors for CNS demyelination.
Academic Article Coffee, tea, and sugar-sweetened carbonated soft drink intake and pancreatic cancer risk: a pooled analysis of 14 cohort studies.
Academic Article Interactions between plasma levels of 25-hydroxyvitamin D, insulin-like growth factor (IGF)-1 and C-peptide with risk of colorectal cancer.
Academic Article DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Academic Article Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Academic Article Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: a pooled analysis of 8 prospective studies.
Academic Article Mixed blessings for middle-aged mothers.
Academic Article Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study.
Academic Article Screening endoscopy and risk of colorectal cancer in United States men.
Academic Article Cancer mortality rates in Menofeia, Egypt: comparison with US mortality rates.
Academic Article Insulin-like growth factor-I and binding protein-3 and risk of cancer.
Academic Article A prospective study of intake of fish and marine fatty acids and prostate cancer.
Academic Article Dietary carotenoids and risk of lung cancer in a pooled analysis of seven cohort studies.
Academic Article Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Academic Article Role of diet in prostate cancer development and progression.
Academic Article Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma.
Academic Article Calcium and vitamin D intakes in relation to risk of distal colorectal adenoma in women.
Academic Article Body mass index, physical activity, and risk of multiple myeloma.
Academic Article Aspirin dose and duration of use and risk of colorectal cancer in men.
Academic Article Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Academic Article Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.
Academic Article A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Academic Article A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.
Academic Article Passive smoking and pancreatic cancer in women: a prospective cohort study.
Academic Article Total antioxidant capacity intake and colorectal cancer risk in the Health Professionals Follow-up Study.
Academic Article Intakes of vitamins and minerals in relation to urinary incontinence, voiding, and storage symptoms in women: a cross-sectional analysis from the Boston Area Community Health survey.
Academic Article Reported behavior of eating anything at anytime and risk of colorectal cancer in women.
Academic Article Measurement of GSTP1 promoter methylation in body fluids may complement PSA screening: a meta-analysis.
Academic Article Aspirin use, body mass index, physical activity, plasma C-peptide, and colon cancer risk in US health professionals.
Academic Article Estimating the global and regional burden of suboptimal nutrition on chronic disease: methods and inputs to the analysis.
Academic Article Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer.
Academic Article Expression profiling of archival tumors for long-term health studies.
Academic Article Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.
Academic Article A prospective study of cigarette smoking and risk of colorectal adenoma and colorectal cancer in U.S. women.
Academic Article A comparison of prospective and retrospective assessments of diet in the study of breast cancer.
Academic Article Harvard Report on Cancer Prevention. Volume 3: prevention of colon cancer in the United States.
Academic Article A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk.
Academic Article Intakes of fruits, vegetables, and related nutrients and the risk of non-Hodgkin's lymphoma among women.
Academic Article Fruit, vegetables, dietary fiber, and risk of colorectal cancer.
Academic Article Fruit and vegetable consumption and colorectal cancer incidence.
Academic Article Dietary meat, dairy products, fat, and cholesterol and pancreatic cancer risk in a prospective study.
Academic Article Fatty acids and risk of prostate cancer in a nested case-control study in male smokers.
Academic Article Height, predictors of C-peptide and cancer risk in men.
Academic Article Serum C-reactive protein concentration and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey (NHANES III).
Academic Article Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine.
Academic Article Commentary: vitamin D and colorectal cancer--twenty-five years later.
Academic Article A prospective study of risk factors for erectile dysfunction.
Academic Article Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Academic Article Gonorrhea, syphilis, clinical prostatitis, and the risk of prostate cancer.
Academic Article Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies.
Academic Article Validation of a food frequency questionnaire measurement of selected nutrients using biological markers in African-American men.
Academic Article Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies.
Academic Article Medical history and etiology of prostate cancer.
Academic Article Variations in plasma lycopene and specific isomers over time in a cohort of U.S. men.
Academic Article Association between serum concentrations of micronutrients and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey.
Academic Article Re: Heme iron, zinc, alcohol consumption, and risk of colon cancer.
Academic Article A prospective study of parental history of myocardial infarction and coronary artery disease in men.
Academic Article Are findings from studies of obesity and prostate cancer really in conflict?
Academic Article Calcium and dairy food intakes are inversely associated with colorectal cancer risk in the Cohort of Swedish Men.
Academic Article A prospective cohort study of red wine consumption and risk of prostate cancer.
Academic Article Metabolic syndrome, hyperinsulinemia, and colon cancer: a review.
Academic Article Dietary macronutrients, cholesterol, and sodium and lower urinary tract symptoms in men.
Academic Article Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis.
Academic Article Prospective study of meat intake and dietary nitrates, nitrites, and nitrosamines and risk of adult glioma.
Academic Article Acne and risk of prostate cancer.
Academic Article Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers.
Academic Article Body fatness during childhood and adolescence, adult height, and risk of colorectal adenoma in women.
Academic Article Joint association of glycemic load and alcohol intake with type 2 diabetes incidence in women.
Academic Article Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium.
Academic Article No association between garlic intake and risk of colorectal cancer.
Academic Article The CAG repeat within the androgen receptor gene and its relationship to prostate cancer.
Academic Article Leisure-time physical activity, body size, and colon cancer in women. Nurses' Health Study Research Group.
Academic Article Peptic ulcer disease and the risk of bladder cancer in a prospective study of male health professionals.
Academic Article Plasma 1,25-dihydroxy- and 25-hydroxyvitamin D and subsequent risk of prostate cancer.
Academic Article Folate intake and risk of breast cancer characterized by hormone receptor status.
Academic Article Sugar-sweetened soft drink consumption and risk of pancreatic cancer in two prospective cohorts.
Academic Article Total fluid intake and use of individual beverages and risk of renal cell cancer in two large cohorts.
Academic Article Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway.
Academic Article Glycosylated hemoglobin and risk of colorectal cancer and adenoma (United States).
Academic Article Association of bowel movement frequency and use of laxatives with the occurrence of symptomatic gallstone disease in a prospective study of women.
Academic Article Body weight and colorectal cancer risk in a cohort of Swedish women: relation varies by age and cancer site.
Academic Article Viral infections and lower urinary tract symptoms in the third national health and nutrition examination survey.
Academic Article Multiple loci identified in a genome-wide association study of prostate cancer.
Academic Article Risk of bladder cancer by geographic region in a U.S. cohort of male health professionals.
Academic Article The association of treatment-related symptoms with quality-of-life outcomes for localized prostate carcinoma patients.
Academic Article Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer.
Academic Article Prospective study of alcohol consumption and risk of coronary disease in men.
Academic Article Body mass index and risk of prostate cancer in U.S. health professionals.
Academic Article Prospective study of selenium levels in toenails and risk of coronary heart disease in men.
Academic Article Interrelation of energy intake, body size, and physical activity with prostate cancer in a large prospective cohort study.
Academic Article Alcohol intake and colorectal cancer: a pooled analysis of 8 cohort studies.
Academic Article Frequent nut consumption and decreased risk of cholecystectomy in women.
Academic Article Dietary protein and the risk of cholecystectomy in a cohort of US women: the Nurses' Health Study.
Academic Article A prospective study of folate intake and the risk of pancreatic cancer in men and women.
Academic Article Should smokers be considered a high-risk group for colorectal cancer?
Academic Article Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993-2004.
Academic Article Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers.
Academic Article Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs.
Academic Article Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer.
Academic Article Genetic variants in the UGT1A6 enzyme, aspirin use, and the risk of colorectal adenoma.
Academic Article Dietary intake of Cruciferous vegetables, Glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population.
Academic Article Association of cigarette smoking, alcohol consumption and physical activity with lower urinary tract symptoms in older American men: findings from the third National Health And Nutrition Examination Survey.
Academic Article Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer.
Academic Article Recall and selection bias in reporting past alcohol consumption among breast cancer cases.
Academic Article Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies.
Academic Article Diet after diagnosis and the risk of prostate cancer progression, recurrence, and death (United States).
Academic Article p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer.
Academic Article A meta-analysis of diabetes mellitus and the risk of prostate cancer.
Academic Article Intakes of fruits, vegetables, vitamins A, C, and E, and carotenoids and risk of renal cell cancer.
Academic Article Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men.
Academic Article Prospective study of cigarette smoking and adult glioma: dosage, duration, and latency.
Academic Article Alcohol intake and renal cell cancer in a pooled analysis of 12 prospective studies.
Academic Article Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: reanalysis of Women's Health Initiative randomized trial.
Academic Article Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic.
Academic Article The joint association of eating frequency and diet quality with colorectal cancer risk in the Health Professionals Follow-up Study.
Academic Article Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study.
Academic Article Association between sex hormones and colorectal cancer risk in men and women.
Academic Article Nutrients related to one-carbon metabolism and risk of renal cell cancer.
Academic Article Prospective study of plasma fatty acids and risk of prostate cancer.
Academic Article Glycaemic index and glycaemic load in relation to risk of diabetes-related cancers: a meta-analysis.
Academic Article Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Academic Article Prospective study of intake of fruit, vegetables, and carotenoids and the risk of adult glioma.
Academic Article A review of the relationship between tooth loss, periodontal disease, and cancer.
Academic Article Meat consumption, heterocyclic amines, NAT2, and the risk of breast cancer.
Academic Article Body mass index and Barrett's oesophagus in women.
Academic Article Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies.
Academic Article Prospective weight change and colon cancer risk in male US health professionals.
Academic Article Plasma C-peptide is inversely associated with calcium intake in women and with plasma 25-hydroxy vitamin D in men.
Academic Article Statin use and the risk of cholecystectomy in women.
Academic Article ABO blood group and the risk of pancreatic cancer.
Academic Article Gleason score and lethal prostate cancer: does 3 + 4 = 4 + 3?
Academic Article Common polymorphisms in the adiponectin and its receptor genes, adiponectin levels and the risk of prostate cancer.
Academic Article Body mass index and risk of colorectal cancer according to fatty acid synthase expression in the nurses' health study.
Academic Article Commentary: Lifestyle factors and colorectal cancer microsatellite instability--molecular pathological epidemiology science, based on unique tumour principle.
Academic Article Dietary fatty acid intake and prostate cancer survival in Örebro County, Sweden.
Academic Article Obesity and benign prostatic hyperplasia.
Academic Article Aspirin use and the risk for colorectal cancer and adenoma in male health professionals.
Academic Article Dietary iron intake and risk of coronary disease among men.
Academic Article Circulating prediagnostic interleukin-6 and C-reactive protein and prostate cancer incidence and mortality.
Academic Article A prospective study of lifetime physical activity and prostate cancer incidence and mortality.
Academic Article Genome-wide association study of prostate cancer mortality.
Academic Article Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up Study.
Academic Article Folate intake and risk of pancreatic cancer: pooled analysis of prospective cohort studies.
Academic Article Physical activity, sedentary behavior, and leukocyte telomere length in women.
Academic Article Association of IGF-1 and IGFBP-3 with lower urinary tract symptoms in the third national health and nutrition examination survey.
Academic Article The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.
Academic Article Manganese superoxide dismutase (MnSOD) gene polymorphism, interactions with carotenoid levels and prostate cancer risk.
Academic Article Diet, alcohol, and smoking and the occurrence of hyperplastic polyps of the colon and rectum (United States).
Academic Article Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men.
Academic Article Dietary intake of marine n-3 fatty acids, fish intake, and the risk of coronary disease among men.
Academic Article Calcium, vitamin D, dairy foods, and the occurrence of colorectal adenomas among men and women in two prospective studies.
Academic Article A prospective cohort study of vasectomy and prostate cancer in US men.
Academic Article Variation in KLK genes, prostate-specific antigen and risk of prostate cancer.
Academic Article Smoking and aggressive prostate cancer: a review of the epidemiologic evidence.
Academic Article A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma.
Academic Article Physical activity and male colorectal cancer survival.
Academic Article PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Academic Article Dietary insulin load, dietary insulin index, and colorectal cancer.
Academic Article Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding.
Academic Article Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality.
Academic Article Cholelithiasis and the risk of nephrolithiasis.
Academic Article Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma.
Academic Article Epidemiology of vitamin D and colorectal cancer.
Academic Article A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer.
Academic Article Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Academic Article Meta-analysis of coffee consumption and risk of colorectal cancer.
Academic Article Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States.
Academic Article Prospective study of bowel movement, laxative use, and risk of colorectal cancer among women.
Academic Article Prospective study of dietary supplements, macronutrients, micronutrients, and risk of bladder cancer in US men.
Academic Article Milk intake, circulating levels of insulin-like growth factor-I, and risk of colorectal cancer in men.
Academic Article The epidemic of prostate cancer and the medical literature: a causal association?
Academic Article Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer.
Academic Article The androgen receptor gene GGN microsatellite and prostate cancer risk.
Academic Article Smoking and risk of total and fatal prostate cancer in United States health professionals.
Academic Article CAG repeat within the androgen receptor gene and incidence of surgery for benign prostatic hyperplasia in U.S. physicians.
Academic Article A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men.
Academic Article Hemochromatosis gene mutations, body iron stores, dietary iron, and risk of colorectal adenoma in women.
Academic Article Central adiposity, regional fat distribution, and the risk of cholecystectomy in women.
Academic Article Folate fortification, plasma folate, homocysteine and colorectal adenoma recurrence.
Academic Article Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer.
Academic Article Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level.
Academic Article The prevention of colorectal cancer by aspirin use.
Academic Article Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study.
Academic Article Plasma 1,25-dihydroxy- and 25-hydroxyvitamin D and adenomatous polyps of the distal colorectum.
Academic Article A prospective study on intake of animal products and risk of prostate cancer.
Academic Article Gallstones, cholecystectomy, and the risk for developing pancreatic cancer.
Academic Article Aspirin use in relation to risk of prostate cancer.
Academic Article Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men.
Academic Article Height and the survival of prostate cancer patients.
Academic Article Aspirin and the risk of colorectal cancer in women.
Academic Article A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis.
Academic Article The relation of physical activity to risk for symptomatic gallstone disease in men.
Academic Article Alcohol consumption, cigarette smoking, and risk of benign prostatic hyperplasia.
Academic Article Fluid intake and the risk of bladder cancer in men.