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One or more keywords matched the following items that are connected to Chorev, Michael
Item TypeName
Academic Article Evaluation in vivo of a potent parathyroid hormone antagonist: [Nle8,18,D-Trp12,Tyr34]bPTH(7-34)NH2.
Academic Article The human PTH2 receptor: binding and signal transduction properties of the stably expressed recombinant receptor.
Academic Article Synthesis of fully active biotinylated analogues of parathyroid hormone and parathyroid hormone-related protein as tools for the characterization of parathyroid hormone receptors.
Academic Article Role of glycosylation in expression and function of the human parathyroid hormone/parathyroid hormone-related protein receptor.
Academic Article Conformational studies of a potent Leu11,D-Trp12-containing lactam-bridged parathyroid hormone-related protein-derived antagonist.
Academic Article Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations.
Academic Article Direct identification of two contact sites for parathyroid hormone (PTH) in the novel PTH-2 receptor using photoaffinity cross-linking.
Academic Article Conformational studies of mono- and bicyclic parathyroid hormone-related protein-derived agonists.
Academic Article Conformational characterization of a peptide mimetic of the third cytoplasmic loop of the G-protein coupled parathyroid hormone/parathyroid hormone related protein receptor.
Academic Article Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop.
Academic Article Direct mapping of an agonist-binding domain within the parathyroid hormone/parathyroid hormone-related protein receptor by photoaffinity crosslinking.
Academic Article Conformational studies of a bicyclic, lactam-constrained parathyroid hormone-related protein-derived agonist.
Academic Article Biological activity of parathyroid hormone antagonists substituted at position 13.
Academic Article New insights into interactions between the human PTH/PTHrP receptor and agonist/antagonist binding.
Academic Article Photoaffinity cross-linking identifies differences in the interactions of an agonist and an antagonist with the parathyroid hormone/parathyroid hormone-related protein receptor.
Academic Article Structure-function studies of analogues of parathyroid hormone (PTH)-1-34 containing beta-amino acid residues in positions 11-13.
Academic Article Differential transcriptional effects of PTH and estrogen during anabolic bone formation.
Academic Article Endocytosis of ligand-human parathyroid hormone receptor 1 complexes is protein kinase C-dependent and involves beta-arrestin2. Real-time monitoring by fluorescence microscopy.
Academic Article A novel, mild, specific and indirect maleimido-based radioiodolabeling method. Radiolabeling of analogs derived from parathyroid hormone (PTH) and PTH-related protein (PTHrP).
Academic Article The effect of PTH antagonist BIM-44002 on serum calcium and PTH levels in hypercalcemic hyperparathyroid patients.
Academic Article Intermittently administered parathyroid hormone 1-34 reverses bone loss and structural impairment in orchiectomized adult rats.
Academic Article Structure-function relationship studies of bovine parathyroid hormone [bPTH(1-34)] analogues containing alpha-amino-iso-butyric acid (Aib) residues.
Academic Article Inositol 1-,4-,5-trisphosphate-dependent Ca2+ signaling by the recombinant human PTH/PTHrP receptor stably expressed in a human kidney cell line.
Academic Article Mono- and bicyclic analogs of parathyroid hormone-related protein. 2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations.
Academic Article Binding domain of human parathyroid hormone receptor: from conformation to function.
Academic Article Conformational studies of parathyroid hormone (PTH)/PTH-related protein (PTHrP) point-mutated hybrids.
Academic Article The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation.
Academic Article Backbone dynamics of human parathyroid hormone (1-34): flexibility of the central region under different environmental conditions.
Academic Article Effects of hydrophobic substitutions at position 18 on the potency of parathyroid hormone antagonists.
Academic Article Development of a photoreactive parathyroid hormone antagonist to probe antagonist-receptor bimolecular interaction.
Academic Article Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes.
Academic Article Structure-function relationship studies of PTH(1-11) analogues containing sterically hindered dipeptide mimetics.
Academic Article Conventional and microwave-assisted SPPS approach: a comparative synthesis of PTHrP(1-34)NH(2).
Academic Article A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2.
Academic Article Solvent independent conformational propensities of [1,2,3]triazolyl-bridged parathyroid hormone-related peptide-derived cyclo-nonapeptide analogues.
Academic Article Mono- and bicyclic analogs of parathyroid hormone-related protein. 1. Synthesis and biological studies.
Academic Article Conformational studies of RS-66271, an analog of parathyroid hormone-related protein with pronounced bone anabolic activity.
Academic Article Arginine 186 in the extracellular N-terminal region of the human parathyroid hormone 1 receptor is essential for contact with position 13 of the hormone.
Academic Article Addressing the tertiary structure of human parathyroid hormone-(1-34).
Academic Article Cyclic parathyroid hormone related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization.
Academic Article Does simvastatin stimulate bone formation in vivo?
Academic Article Approaches to studying the biomolecular interaction between the parathyroid hormone/parathyroid hormone-related protein receptor and its ligands.
Academic Article Structure-function relationship study of parathyroid hormone (1-11) analogues containing D-AA.
Academic Article Downregulation of parathyroid hormone receptors in renal membranes from aged rats.
Academic Article Parathyroid hormone 1 receptor: insights into structure and function.
Academic Article Evaluation of novel parathyroid hormone analogs using a bovine renal membrane receptor binding assay.
Academic Article Conformational studies of parathyroid hormone (PTH)/PTH-related protein (PTHrp) chimeric peptides.
Academic Article Human parathyroid hormone 1-34 reverses bone loss in ovariectomized mice.
Academic Article Conformational and biological characterization of human parathyroid hormone hPTH(1-34) analogues containing beta-amino acid residues in positions 17-19.
Academic Article Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: a correlative micro-computed tomographic and biomechanical analysis.
Academic Article Modifications of position 12 in parathyroid hormone and parathyroid hormone related protein: toward the design of highly potent antagonists.
Academic Article Generation and characterization of human kidney cell lines stably expressing recombinant human PTH/PTHrP receptor: lack of interaction with a C-terminal human PTH peptide.
Academic Article Distribution and pharmacokinetics of a potent peptide antagonist of parathyroid hormone and parathyroid hormone-related protein in the rat.
Academic Article Conformation of parathyroid hormone antagonists by CD, NMR, and molecular dynamics simulations.
Academic Article Probing the bimolecular interactions of parathyroid hormone and the human parathyroid hormone/parathyroid hormone-related protein receptor. 2. Cloning, characterization, and photoaffinity labeling of the recombinant human receptor.
Academic Article Circular dichroism (CD) studies of antagonists derived from parathyroid hormone-related protein.
Academic Article Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies.
Academic Article Probing the bimolecular interactions of parathyroid hormone with the human parathyroid hormone/parathyroid hormone-related protein receptor. 1. Design, synthesis and characterization of photoreactive benzophenone-containing analogs of parathyroid hormone.
Academic Article 3-(3'-fluorenyl-9'-oxo)-L-alanine: a novel photoreactive conformationally constrained amino acid.
Academic Article Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: spatial proximity between Lys(27) (of the hormone principal binding domain) and leu(261) (of the first extracellular loop) of the human PTH1 receptor.
Academic Article Bioactive N-terminal undecapeptides derived from parathyroid hormone: the role of alpha-helicity.
Concept Receptors, Parathyroid Hormone
Concept Parathyroid Hormone-Related Protein
Concept Receptor, Parathyroid Hormone, Type 2
Concept Parathyroid Hormone
Concept Receptor, Parathyroid Hormone, Type 1
Academic Article Direct Identification of Two Contact Sites for Parathyroid Hormone (PTH) in the Novel PTH-2 Receptor using Photoaffinity Cross-Linking1.
Search Criteria
  • Parathyroid Hormone
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.