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One or more keywords matched the following items that are connected to Michor, Franziska
Item TypeName
Academic Article Evolution: the good, the bad and the lonely.
Academic Article Dynamics of chronic myeloid leukaemia.
Academic Article Evolutionary dynamics of invasion and escape.
Academic Article Local regulation of homeostasis favors chromosomal instability.
Academic Article Stochastic tunnels in evolutionary dynamics.
Academic Article Dynamics of colorectal cancer.
Academic Article Evolution of resistance to targeted anti-cancer therapies during continuous and pulsed administration strategies.
Academic Article Chromosomal instability and human cancer.
Academic Article Successful therapy must eradicate cancer stem cells.
Academic Article Mathematical models of targeted cancer therapy.
Academic Article Virus evolution within patients increases pathogenicity.
Academic Article The age incidence of chronic myeloid leukemia can be explained by a one-mutation model.
Academic Article Chronic myeloid leukemia blast crisis arises from progenitors.
Academic Article A progenitor cell origin of myeloid malignancies.
Academic Article Dynamics of metastasis suppressor gene inactivation.
Academic Article Stochastic dynamics of cancer initiation.
Academic Article A mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis.
Academic Article Evolutionary dynamics of intratumor heterogeneity.
Academic Article Evolutionary dynamics of tumor suppressor gene inactivation.
Academic Article Population genetics of tumor suppressor genes.
Academic Article The emergence of tumor metastases.
Academic Article Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer.
Academic Article Stochastic elimination of cancer cells.
Academic Article The evolution of two mutations during clonal expansion.
Academic Article A mathematical framework to determine the temporal sequence of somatic genetic events in cancer.
Academic Article Can chromosomal instability initiate tumorigenesis?
Academic Article Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies.
Academic Article Evolutionary theory of cancer.
Academic Article Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib.
Academic Article Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis.
Academic Article Evolution of resistance to anti-cancer therapy during general dosing schedules.
Academic Article Intratumor heterogeneity in evolutionary models of tumor progression.
Academic Article Genetic instability and the quasispecies model.
Academic Article Somatic selection for and against cancer.
Academic Article Some basic properties of immune selection.
Academic Article The therapeutic implications of plasticity of the cancer stem cell phenotype.
Academic Article Mathematical models of cancer stem cells.
Academic Article Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.
Academic Article A race between tumor immunoescape and genome maintenance selects for optimum levels of (epi)genetic instability.
Academic Article Quantitative approaches to analyzing imatinib-treated chronic myeloid leukemia.
Academic Article A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1).
Academic Article The linear process of somatic evolution.
Academic Article Linear model of colon cancer initiation.
Academic Article Stochastic dynamics of metastasis formation.
Academic Article Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells.
Academic Article DNA secondary structures and epigenetic determinants of cancer genome evolution.
Academic Article Evolutionary dynamics of tumor progression with random fitness values.
Academic Article Effects of pharmacokinetic processes and varied dosing schedules on the dynamics of acquired resistance to erlotinib in EGFR-mutant lung cancer.
Academic Article Synergy and discounting of cooperation in social dilemmas.
Academic Article Genetic instability and clonal expansion.
Academic Article Selection pressure exerted by imatinib therapy leads to disparate outcomes of imatinib discontinuation trials.
Academic Article Evolutionary dynamics of escape from biomedical intervention.
Academic Article Evolution of resistance during clonal expansion.
Academic Article (A)symmetric stem cell replication and cancer.
Academic Article The evolution of tumor metastases during clonal expansion.
Academic Article The probable cell of origin of NF1- and PDGF-driven glioblastomas.
Concept Models, Molecular
Concept Models, Theoretical
Concept Logistic Models
Concept Models, Genetic
Concept Models, Immunological
Concept Models, Psychological
Concept Linear Models
Concept Disease Models, Animal
Concept Models, Statistical
Concept Models, Biological
Concept Proportional Hazards Models
Academic Article Patterns of proliferative activity in the colonic crypt determine crypt stability and rates of somatic evolution.
Academic Article A physical sciences network characterization of non-tumorigenic and metastatic cells.
Academic Article Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma.
Academic Article Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules.
Academic Article Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.
Academic Article Histone modifications are associated with transcript isoform diversity in normal and cancer cells.
Academic Article FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder.
Academic Article Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
Academic Article Evolution of acquired resistance to anti-cancer therapy.
Academic Article Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity.
Academic Article Dynamics of chronic myeloid leukemia response to dasatinib, nilotinib, and high-dose imatinib.
Academic Article Stochastic tunneling and metastable states during the somatic evolution of cancer.
Academic Article Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
Academic Article JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.
Academic Article An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer.
Academic Article Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients.
Academic Article The mathematics of cancer: integrating quantitative models.
Academic Article Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the Effort.
Academic Article Optimization of radiation dosing schedules for proneural glioblastoma.
Academic Article Stochastic Tunneling of Two Mutations in a Population of Cancer Cells.
Academic Article Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease.
Academic Article Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution.
Academic Article Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells.
Academic Article Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk.
Academic Article Pharmacokinetics and Drug Interactions Determine Optimum Combination Strategies in Computational Models of Cancer Evolution.
Academic Article Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model.
Academic Article The Warburg effect: persistence of stem-cell metabolism in cancers as a failure of differentiation.
Academic Article Mathematical modeling identifies optimum lapatinib dosing schedules for the treatment of glioblastoma patients.
Academic Article A PDGFRa-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Academic Article Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution.
Academic Article Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages.
Academic Article Computational Model of Progression to Multiple Myeloma Identifies Optimum Screening Strategies.
Academic Article Stochastic Evolution of Pancreatic Cancer Metastases During Logistic Clonal Expansion.
Academic Article Computational modeling of pancreatic cancer patients receiving FOLFIRINOX and gemcitabine-based therapies identifies optimum intervention strategies.
Academic Article Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms.
Academic Article Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer.
Academic Article Accelerating massively parallel hemodynamic models of coarctation of the aorta using neural networks.
Academic Article Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance.
Academic Article Circadian clock effects on cellular proliferation: Insights from theory and experiments.
Academic Article Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML.
Academic Article Breast tumours maintain a reservoir of subclonal diversity during expansion.
Academic Article Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma.
Academic Article Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer.
Search Criteria
  • Modelling
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.