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One or more keywords matched the following items that are connected to Elledge, Stephen
Item TypeName
Academic Article RNA interference screen for human genes associated with West Nile virus infection.
Academic Article Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate.
Academic Article Dicer is essential for mouse development.
Academic Article A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
Academic Article A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal.
Academic Article A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.
Academic Article Identification of host proteins required for HIV infection through a functional genomic screen.
Academic Article A genome-wide genetic screen for host factors required for hepatitis C virus propagation.
Academic Article A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells.
Academic Article Dissecting cancer pathways and vulnerabilities with RNAi.
Academic Article Lessons from Nature: microRNA-based shRNA libraries.
Academic Article A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Academic Article Reactivation of latent HIV-1 by inhibition of BRD4.
Academic Article Cell biology forum: Genome-wide view of mitosis.
Academic Article STOP gene Phactr4 is a tumor suppressor.
Academic Article Second-generation shRNA libraries covering the mouse and human genomes.
Academic Article Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy.
Academic Article Multiple tumor suppressor pathways negatively regulate telomerase.
Academic Article A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.
Academic Article A resource for large-scale RNA-interference-based screens in mammals.
Academic Article CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Academic Article Profiling essential genes in human mammary cells by multiplex RNAi screening.
Academic Article Functional identification of optimized RNAi triggers using a massively parallel sensor assay.
Academic Article SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.
Academic Article Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila.
Academic Article A genetic screen for candidate tumor suppressors identifies REST.
Academic Article A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.
Academic Article The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Concept RNA Interference
Academic Article A role for PVRL4-driven cell-cell interactions in tumorigenesis.
Academic Article Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction.
Academic Article GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.
Academic Article RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways.
Academic Article Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.
Academic Article FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency.
Grant A multiplex genome-wide shRNA screening platform for cancer-lethal gene discovery
Academic Article Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Academic Article Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns.
Academic Article A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach.
Academic Article Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Academic Article Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells.
Academic Article The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning.
Search Criteria
  • RNA Interference
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.