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One or more keywords matched the following items that are connected to Elledge, Stephen
Item TypeName
Academic Article Cdk inhibitors in development and cancer.
Academic Article Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
Academic Article Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome.
Academic Article SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.
Academic Article A question of balance: the role of cyclin-kinase inhibitors in development and tumorigenesis.
Academic Article Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
Academic Article A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1.
Academic Article CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.
Academic Article Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development.
Academic Article SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
Academic Article Cell cycle checkpoints: preventing an identity crisis.
Academic Article How the cyclin became a cyclin: regulated proteolysis in the cell cycle.
Academic Article Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
Academic Article Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Academic Article Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.
Academic Article The role of Cdk7 in CAK function, a retro-retrospective.
Academic Article Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle.
Academic Article Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.
Academic Article G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts.
Academic Article p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.
Academic Article Cyclin F disruption compromises placental development and affects normal cell cycle execution.
Academic Article The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit.
Academic Article The DASH complex component Ask1 is a cell cycle-regulated Cdk substrate in Saccharomyces cerevisiae.
Academic Article Human cyclin F.
Academic Article p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells.
Academic Article Selective maternal-allele loss in human lung cancers of the maternally expressed p57KIP2 gene at 11p15.5.
Academic Article Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
Academic Article Amplification of cyclin genes in colorectal carcinomas.
Academic Article Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.
Academic Article The role of protein stability in the cell cycle and cancer.
Academic Article Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Academic Article Cyclin D1 provides a link between development and oncogenesis in the retina and breast.
Academic Article Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.
Academic Article A quantitative atlas of mitotic phosphorylation.
Academic Article Inhibition of cyclin-dependent kinases by p21.
Academic Article The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.
Academic Article Purification and analysis of CIP/KIP proteins.
Academic Article F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.
Academic Article Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity.
Academic Article Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo.
Academic Article Mitotic treasures in the nucleolus.
Academic Article Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.
Academic Article In vivo gene therapy with p53 or p21 adenovirus for prostate cancer.
Academic Article Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control.
Academic Article p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
Academic Article p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step.
Academic Article Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Concept Cyclin B
Concept Cyclin E
Concept Cyclin-Dependent Kinase 2
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Cyclin-Dependent Kinase 8
Concept Cyclin D1
Concept Cyclin-Dependent Kinase 6
Concept Cyclin G
Concept Cyclin T
Concept Cyclin D2
Concept Cyclin G1
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Cyclin-Dependent Kinase Inhibitor Proteins
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Cyclin-Dependent Kinase 4
Concept Cyclin-Dependent Kinase Inhibitor p57
Concept Cyclin-Dependent Kinases
Academic Article The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.
Academic Article FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency.
Academic Article Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is.
Search Criteria
  • Cyclin E
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.