Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Elledge, Stephen
Item TypeName
Academic Article Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability.
Academic Article MDC1 is a mediator of the mammalian DNA damage checkpoint.
Academic Article Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
Academic Article BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Academic Article 53BP1, a mediator of the DNA damage checkpoint.
Academic Article Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Academic Article Direct DNA binding by Brca1.
Academic Article The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients.
Academic Article Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
Academic Article Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.
Academic Article ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Academic Article Cancer. BRCA2 enters the fray.
Academic Article Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
Academic Article BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly.
Academic Article BRCA1 as tumor suppressor: lord without its RING?
Academic Article NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.
Concept BRCA1 Protein
Academic Article Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Search Criteria
  • BRCA1 Protein
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.