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One or more keywords matched the following items that are connected to Anderson, Kenneth
Item TypeName
Academic Article Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma.
Academic Article The biological sequelae of stromal cell-derived factor-1alpha in multiple myeloma.
Academic Article Cytokines and signal transduction.
Academic Article Synopsis of a research roundtable presented on cell signaling in myeloma: regulation of growth and apoptosis--opportunities for new drug discovery.
Academic Article Novel therapeutic approaches for multiple myeloma.
Academic Article GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment.
Academic Article Novel biologically based therapeutic strategies in myeloma.
Academic Article 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells.
Academic Article Targeting the vascular endothelial growth factor pathway in the treatment of multiple myeloma.
Academic Article Molecular mechanisms of novel therapeutic approaches for multiple myeloma.
Academic Article Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.
Academic Article Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.
Academic Article Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo.
Academic Article New frontiers in the treatment of multiple myeloma.
Academic Article BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.
Academic Article Inhibition of VEGF signaling pathways in multiple myeloma and other malignancies.
Academic Article Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma.
Academic Article Fatty acid synthase is a novel therapeutic target in multiple myeloma.
Academic Article microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia.
Academic Article Functional significance of novel neurotrophin-1/B cell-stimulating factor-3 (cardiotrophin-like cytokine) for human myeloma cell growth and survival.
Academic Article Targeting signalling pathways for the treatment of multiple myeloma.
Academic Article From the bench to the bedside: emerging new treatments in multiple myeloma.
Academic Article The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications.
Academic Article Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment.
Academic Article Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.
Academic Article Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.
Academic Article Moving disease biology from the laboratory to the clinic.
Academic Article Characterization of the MM.1 human multiple myeloma (MM) cell lines: a model system to elucidate the characteristics, behavior, and signaling of steroid-sensitive and -resistant MM cells.
Academic Article Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
Academic Article Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Academic Article A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells.
Academic Article Lenalidomide and thalidomide: mechanisms of action--similarities and differences.
Academic Article Novel therapeutic avenues in myeloma: changing the treatment paradigm.
Academic Article Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications.
Academic Article Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells.
Academic Article Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications.
Academic Article Initial genome sequencing and analysis of multiple myeloma.
Academic Article Targeting NF-kappaB in Waldenstrom macroglobulinemia.
Academic Article Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma.
Academic Article Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.
Academic Article Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.
Academic Article Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.
Academic Article Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
Academic Article Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance.
Academic Article Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma.
Academic Article Blockade of XBP1 splicing by inhibition of IRE1a is a promising therapeutic option in multiple myeloma.
Academic Article Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment.
Academic Article Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
Academic Article Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells.
Academic Article The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Academic Article Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
Academic Article A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma.
Academic Article FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
Academic Article Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells.
Academic Article Proteomic analyses in Waldenstrom's macroglobulinemia and other plasma cell dyscrasias.
Academic Article Dual inhibition of canonical and noncanonical NF-?B pathways demonstrates significant antitumor activities in multiple myeloma.
Academic Article Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays.
Academic Article CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
Academic Article Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
Academic Article Antimyeloma activity of heat shock protein-90 inhibition.
Academic Article Lenalidomide and thalidomide: an evolving paradigm for the management of multiple myeloma.
Academic Article Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions.
Academic Article Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
Academic Article The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.
Academic Article Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Academic Article Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells.
Academic Article Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma.
Academic Article Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications.
Academic Article Targeting the UPS as therapy in multiple myeloma.
Academic Article A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways.
Academic Article Inhibition of the TGF-beta signaling pathway in tumor cells.
Academic Article Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.
Academic Article Molecular sequelae of proteasome inhibition in human multiple myeloma cells.
Academic Article Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment.
Academic Article Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications.
Concept Signal Transduction
Academic Article Drug insight: thalidomide as a treatment for multiple myeloma.
Academic Article A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.
Academic Article Decoding the pathophysiology and the genetics of multiple myeloma to identify new therapeutic targets.
Academic Article Delineating the mTOR kinase pathway using a dual TORC1/2 inhibitor, AZD8055, in multiple myeloma.
Academic Article Understanding biology to tackle the disease: Multiple myeloma from bench to bedside, and back.
Academic Article Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.
Academic Article Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma.
Academic Article Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.
Academic Article A novel alkylating agent Melflufen induces irreversible DNA damage and cytotoxicity in multiple myeloma cells.
Academic Article p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma.
Academic Article Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Academic Article Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.
Academic Article Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors.
Academic Article APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications.
Academic Article Osteoclast Immunosuppressive Effects in Multiple Myeloma: Role of Programmed Cell Death Ligand 1.
Academic Article Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling.
Academic Article Immunomodulatory drugs activate NK cells via both Zap-70 and cereblon-dependent pathways.
Academic Article Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a.
Academic Article The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications.
Search Criteria
  • Pathway Signal Transduction
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.