Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Kronenberg, Henry
Item TypeName
Academic Article Regulation of HSP70 by PTH: a model of gene regulation not mediated by changes in cAMP levels.
Academic Article Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34.
Academic Article Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development.
Academic Article The history of parathyroid hormone and its receptor: structure-based design of parathyroid hormone analogues.
Academic Article Mutational analysis of the receptor-activating region of human parathyroid hormone.
Academic Article A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.
Academic Article Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor.
Academic Article Parathyroid hormone-related peptide (PTHrP) and parathyroid hormone (PTH)/PTHrP receptor.
Academic Article The carboxy-terminus of parathyroid hormone is essential for hormone processing and secretion.
Academic Article Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone.
Academic Article Parathyroid hormone and osteocalcin--when friends become strangers.
Academic Article Conditionally immortalized murine osteoblasts lacking the type 1 PTH/PTHrP receptor.
Academic Article Parathyroid hormone-related peptide (PTHrP) induces parietal endoderm formation exclusively via the type I PTH/PTHrP receptor.
Academic Article The parathyroid hormone-related protein and Indian hedgehog feedback loop in the growth plate.
Academic Article Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development.
Academic Article The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.
Academic Article Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.
Academic Article Vitamin D receptor binding to the negative human parathyroid hormone vitamin D response element does not require the retinoid x receptor.
Academic Article Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction.
Academic Article The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones.
Academic Article Physiological roles for parathyroid hormone-related protein: lessons from gene knockout mice.
Academic Article Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor.
Academic Article The murine gene encoding parathyroid hormone: genomic organization, nucleotide sequence and transcriptional regulation.
Academic Article Full-length chicken parathyroid hormone. Biosynthesis in Escherichia coli and analysis of biologic activity.
Academic Article A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes.
Academic Article Structure based design of parathyroid hormone analogs.
Academic Article The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation.
Academic Article Signal-selectivity of parathyroid hormone (PTH)/PTH-related peptide receptor-mediated regulation of differentiation in conditionally immortalized growth-plate chondrocytes.
Academic Article Somatic gene transfer in the development of an animal model for primary hyperparathyroidism.
Academic Article The parathyroid hormone (PTH)/PTH-related peptide receptor mediates actions of both ligands in murine bone.
Academic Article 5'-flanking region of the parathyroid hormone gene mediates negative regulation by 1,25-(OH)2 vitamin D3.
Academic Article Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro.
Academic Article Negative regulatory elements in the human parathyroid hormone gene.
Academic Article Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation.
Academic Article Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3.
Academic Article PTH regulates the hematopoietic stem cell niche in bone.
Academic Article Osteoblastic cells regulate the haematopoietic stem cell niche.
Academic Article Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide.
Academic Article Interaction of nascent preproparathyroid hormone molecules with microsomal membranes.
Academic Article ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.
Academic Article Gene encoding parathyroid hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone.
Academic Article Structure, function, and expression of the receptor for parathyroid hormone and parathyroid hormone-related peptide.
Academic Article Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein.
Academic Article Homolog-scanning mutagenesis of the parathyroid hormone (PTH) receptor reveals PTH-(1-34) binding determinants in the third extracellular loop.
Academic Article Regulation of gene transcription and proliferation by parathyroid hormone is blocked in mutant osteoblastic cells resistant to cyclic AMP.
Academic Article Constitutively active PTH/PTHrP receptor specifically expressed in osteoblasts enhances bone formation induced by bone marrow ablation.
Academic Article Anabolic action of parathyroid hormone regulated by the ß2-adrenergic receptor.
Academic Article Parathyroid hormone messenger ribonucleic acid: effects of calcium on cellular regulation in vitro.
Academic Article Parathyroid hormone-related peptide and Indian hedgehog.
Academic Article Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development.
Academic Article The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow.
Academic Article Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.
Academic Article Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development.
Academic Article Tissue and gene specific hypomethylation of the human parathyroid hormone gene: association with parathyroid hormone gene expression in parathyroid glands.
Academic Article Consequences of amino-terminal deletions of preproparathyroid hormone signal sequence.
Academic Article Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death.
Academic Article Parathyroid hormone messenger ribonucleic acid in the rat hypothalamus.
Academic Article Cloning and nucleotide sequence of DNA coding for bovine preproparathyroid hormone.
Academic Article The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C.
Academic Article Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life.
Academic Article Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues.
Academic Article PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways.
Academic Article Monoclonality and abnormal parathyroid hormone genes in parathyroid adenomas.
Academic Article Role of the extracellular regions of the parathyroid hormone (PTH)/PTH-related peptide receptor in hormone binding.
Academic Article The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34).
Academic Article Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor.
Academic Article Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology.
Academic Article The role of the perichondrium in fetal bone development.
Academic Article Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts.
Academic Article Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH.
Academic Article Identification and cell-free translation of mRNA coding for a precursor of parathyroid secretory protein.
Academic Article Signal sequence of human preproparathyroid hormone is inactive in yeast.
Academic Article PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth.
Academic Article A novel population of cells expressing both hematopoietic and mesenchymal markers is present in the normal adult bone marrow and is augmented in a murine model of marrow fibrosis.
Academic Article Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism.
Academic Article Human parathyroid hormone gene (PTH) is on short arm of chromosome 11.
Academic Article The rat, mouse, and human genes encoding the receptor for parathyroid hormone and parathyroid hormone-related peptide are highly homologous.
Academic Article Fetal parathyroids are not required to maintain placental calcium transport.
Academic Article DNA complementary to parathyroid mRNA directs synthesis of pre-proparathyroid hormone in a linked transcription-translation system.
Academic Article PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps.
Academic Article Parathyroid hormone-related protein and Indian hedgehog control the pace of cartilage differentiation.
Academic Article Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development.
Academic Article Biosynthesis of parathyroid hormone.
Academic Article Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.
Academic Article Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man.
Academic Article Synthetic pre-proparathyroid hormone leader sequence inhibits cell-free processing of placental, parathyroid, and pituitary prehormones.
Academic Article Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.
Academic Article Role of parathyroid hormone-related protein in skeletal development.
Academic Article Conditionally immortalized murine bone marrow stromal cells mediate parathyroid hormone-dependent osteoclastogenesis in vitro.
Academic Article Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways.
Academic Article Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy.
Academic Article Parathyroid hormone: chemistry, biosynthesis, and mode of action.
Academic Article Truncation of the carboxyl-terminal region of the rat parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of adenylyl cyclase but not phospholipase C.
Academic Article Inefficient membrane targeting, translocation, and proteolytic processing by signal peptidase of a mutant preproparathyroid hormone protein.
Academic Article Therapeutic targeting of a stem cell niche.
Academic Article Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma.
Academic Article GCMB--another serendipitous gift from evolution to clinical investigators.
Academic Article Reduced expression of the PTH/PTHrP receptor during development of the mammary gland influences the function of the nipple during lactation.
Academic Article PTHrP and skeletal development.
Academic Article Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss.
Academic Article Role of protein kinase-A in homologous down-regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in human osteoblast-like SaOS-2 cells.
Academic Article Familial isolated hypoparathyroidism: a molecular genetic analysis of 8 families with 23 affected persons.
Academic Article Importance of the propeptide sequence of human preproparathyroid hormone for signal sequence function.
Academic Article Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation.
Academic Article Expression of human parathyroid hormone-(1-84) in Escherichia coli as a factor X-cleavable fusion protein.
Academic Article Inhibition of parathyroid hormone bioactivity by human parathyroid hormone (PTH)-(3-84) and PTH-(8-84) synthesized in Escherichia coli.
Academic Article Structure and expression of the human parathyroid hormone gene.
Academic Article Preproparathyroid hormone. A model for analyzing the secretory pathway.
Academic Article Nucleotide sequence of cloned cDNAs encoding chicken preproparathyroid hormone.
Academic Article Human preproparathyroid hormone synthesized in Escherichia coli is transported to the surface of the bacterial inner membrane but not processed to the mature hormone.
Academic Article Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone.
Academic Article biosynthesis of pre-proparathyroid hormone.
Academic Article Intermittent parathyroid hormone administration converts quiescent lining cells to active osteoblasts.
Academic Article Inhibition of parathyroid hormone responsiveness in clonal osteoblastic cells expressing a mutant form of 3',5'-cyclic adenosine monophosphate-dependent protein kinase.
Academic Article T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling.
Academic Article Determinants of [Arg2]PTH-(1-34) binding and signaling in the transmembrane region of the parathyroid hormone receptor.
Academic Article Chromosome mapping of genes on the short arm of human chromosome 11: parathyroid hormone gene is at 11p15 together with the genes for insulin, c-Harvey-ras 1, and beta-hemoglobin.
Academic Article Cell-specific expression of the human parathyroid hormone gene in rat pituitary cells.
Academic Article The rat, mouse and human genes encoding the receptor for parathyroid hormone and parathyroid hormone-related peptide are highly homologous.
Academic Article Disruption of the parathyroid hormone-related peptide gene.
Academic Article Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone-related protein.
Academic Article Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP.
Academic Article Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone.
Academic Article Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells.
Academic Article Messenger ribonucleic acid from tumors associated with humoral hypercalcemia of malignancy directs the synthesis of a secretory parathyroid hormone-like peptide.
Academic Article Nucleotide sequence of the human parathyroid hormone gene.
Academic Article Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region.
Academic Article Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties.
Academic Article Parathyroid hormone biosynthesis: structure and function of biosynthetic precursors.
Academic Article Parathyroid hormone (PTH)-PTH-related peptide hybrid peptides reveal functional interactions between the 1-14 and 15-34 domains of the ligand.
Academic Article Functional analysis of the PTH/PTHrP network of ligands and receptors.
Academic Article Constitutively active parathyroid hormone receptor signaling in cells in osteoblastic lineage suppresses mechanical unloading-induced bone resorption.
Academic Article Myelopoiesis is regulated by osteocytes through Gsa-dependent signaling.
Academic Article Structural requirements of parathyroid hormone/parathyroid hormone-related peptide receptors for phospholipase C activation and regulation of phosphate uptake.
Academic Article Regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid by glucocorticoids and PTH in ROS 17/2.8 and OK cells.
Concept Receptors, Parathyroid Hormone
Concept Parathyroid Hormone-Related Protein
Concept Parathyroid Hormone
Concept Receptor, Parathyroid Hormone, Type 1
Academic Article Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice.
Academic Article The PTH-Gas-protein kinase A cascade controls aNAC localization to regulate bone mass.
Academic Article G-protein stimulatory subunit alpha and Gq/11a G-proteins are both required to maintain quiescent stem-like chondrocytes.
Academic Article Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis.
Academic Article Bone and Mineral Metabolism: Where Are We, Where Are We Going, and How Will We Get There?
Academic Article Loss of Gsa in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy.
Academic Article Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation.
Grant Specialized Center for Cell Based Therapy
Grant HORMONAL CONTROL OF CALCIUM METABOLISM
Grant Hormonal Control of Calcium Metabolism
Grant FUNCTIONS OF PTH/PTHRP RECEPTOR--PTHRP AND PTH IN VIVO
Grant FUNCTION OF STIMULATORY G PROTEIN (GS) IN BONE IN VIVO
Grant Specialized Center for Research in Osteoporosis
Academic Article SIKs control osteocyte responses to parathyroid hormone.
Academic Article The Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Mediates Actions of Both Ligands in Murine Bone* * This work was supported by National Institute of Health Grants DK-47038 and AM-03564.
Academic Article Editorial: Parathyroid Hormone and Osteocalcin-When Friends Become Strangers.
Academic Article Corrigendum: SIKs control osteocyte responses to parathyroid hormone.
Academic Article Parathyroid hormone regulates fates of murine osteoblast precursors in vivo.
Academic Article Regulation of Bone Remodeling by Parathyroid Hormone.
Academic Article [Differential effects on bone and mesenchymal stem cells caused by intermittent and continuous PTH administration].
Academic Article Withdrawal of parathyroid hormone after prolonged administration leads to adipogenic differentiation of mesenchymal precursors in vivo.
Academic Article Resting zone of the growth plate houses a unique class of skeletal stem cells.
Academic Article Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption.
Academic Article PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy.
Academic Article Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.
Search Criteria
  • Parathyroid Hormone
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.