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One or more keywords matched the following properties of VanderWeele, Tyler
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overview Tyler J. VanderWeele, Ph.D., is the John L. Loeb and Frances Lehman Loeb Professor of Epidemiology in the Departments of Epidemiology and Biostatistics at the Harvard T.H. Chan School of Public Health, and Director of the Human Flourishing Program and Co-Director of the Initiative on Health, Religion and Spirituality at Harvard University. He holds degrees from the University of Oxford, University of Pennsylvania, and Harvard University in mathematics, philosophy, theology, finance, and biostatistics. His methodological research is focused on theory and methods for distinguishing between association and causation in the biomedical and social sciences, and, more recently, on measurement theory and the importance of incorporating ideas from causal inference and from analytic philosophy into measure development and evaluation. His empirical research spans psychiatric and social epidemiology; the science of happiness and flourishing; and the study of religion and health, including both religion and population health and the role of religion and spirituality in end-of-life care. He is the recipient of the 2017 Presidents’ Award from the Committee of Presidents of Statistical Societies (COPSS). He has published over three hundred papers in peer-reviewed journals, and is author of the books Explanation in Causal Inference (2015) and Measuring Well-Being (2020), both published by Oxford University Press. Methodology My methodologic research concerns how we distinguish between association and causation in the biomedical and social sciences and the study of the mechanisms by which causal effects arise. The current focus of my work includes the analysis of pathways, assessments of interaction, and the evaluation of spillover effects in which one person's exposure will affect the outcomes of another. My research employs counterfactual theory and ideas from causal inference to clarify and formalize concepts used by epidemiologists, biomedical researchers and social scientists. This methodology in causal inference is relevant for comparative effectiveness research, evaluating and improving policy recommendations, and explaining mechanisms. Empirical Research My empirical work has been in the areas of perinatal, psychiatric and genetic epidemiology; various fields within the social sciences; and the study of religion and health. In perinatal epidemiology, I have worked on evaluating prenatal care indices, on the analysis of trends in birth outcomes, and on assessing the role of preterm birth in mediating the effects of prenatal exposures on mortality outcomes. In genetic epidemiology, I have been studying gene-environment interaction and the pathways by which genetic variants operate. In psychiatric epidemiology, I have been studying the feedback and inter-relationships between depression, loneliness and subjective well-being. My work in the social sciences has included the study of educational interventions, micro-finance programs, social network effects, and judicial decisions. My work in religion and health is oriented towards assessing the mechanisms by which religion and spirituality affect health outcomes.
preferred title John L. Loeb and Frances Lehman Loeb Professor of Epidemiology
One or more keywords matched the following items that are connected to VanderWeele, Tyler
Item TypeName
Academic Article A structural approach to the familial coaggregation of disorders.
Academic Article Marginal structural models for the estimation of direct and indirect effects.
Academic Article Sufficient cause interactions and statistical interactions.
Academic Article Concerning the consistency assumption in causal inference.
Academic Article Sample size and power calculations for case-only interaction studies.
Academic Article A word and that to which it once referred: assessing "biologic" interaction.
Academic Article Components of the indirect effect in vaccine trials: identification of contagion and infectiousness effects.
Academic Article Causal directed acyclic graphs and the direction of unmeasured confounding bias.
Academic Article Alternative assumptions for the identification of direct and indirect effects.
Academic Article Causal interactions in the proportional hazards model.
Academic Article On the nondifferential misclassification of a binary confounder.
Academic Article Using marginal structural models to estimate the direct effect of adverse childhood social conditions on onset of heart disease, diabetes, and stroke.
Academic Article Four types of effect modification: a classification based on directed acyclic graphs.
Academic Article On the relative nature of overadjustment and unnecessary adjustment.
Academic Article Bias formulas for sensitivity analysis of unmeasured confounding for general outcomes, treatments, and confounders.
Academic Article On the distinction between interaction and effect modification.
Academic Article Theorems, proofs, examples, and rules in the practice of epidemiology.
Academic Article Mediation analysis with multiple versions of the mediator.
Academic Article Causal mediation analysis with survival data.
Academic Article The identification of synergism in the sufficient-component-cause framework.
Academic Article A mapping between interactions and interference: implications for vaccine trials.
Academic Article Bounding the infectiousness effect in vaccine trials.
Academic Article Conditioning on intermediates in perinatal epidemiology.
Academic Article Data sharing and scientific replication.
Academic Article Compound treatments and transportability of causal inference.
Academic Article Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants.
Academic Article Bias formulas for sensitivity analysis for direct and indirect effects.
Academic Article The role of measurement error and misclassification in mediation analysis: mediation and measurement error.
Concept Epidemiology
Concept Molecular Epidemiology
Academic Article Policy-relevant proportions for direct effects.
Academic Article A three-way decomposition of a total effect into direct, indirect, and interactive effects.
Academic Article Methodological challenges in mendelian randomization.
Academic Article Identification of natural direct effects when a confounder of the mediator is directly affected by exposure.
Academic Article Effect decomposition in the presence of an exposure-induced mediator-outcome confounder.
Academic Article On the "proportion eliminated" for risk differences versus excess relative risks.
Academic Article Rejoinder: how to reduce racial disparities?: Upon what to intervene?
Academic Article On the causal interpretation of race in regressions adjusting for confounding and mediating variables.
Academic Article A unification of mediation and interaction: a 4-way decomposition.
Academic Article Rejoinder: interacting on interactions.
Academic Article Attributing effects to interactions.
Academic Article The authors respond.
Academic Article Causal mediation analysis in the presence of a mismeasured outcome.
Academic Article Mediators of First- Versus Second-generation Antipsychotic-related Mortality in Older Adults.
Academic Article SAS macro for causal mediation analysis with survival data.
Academic Article Alternative decompositions for attributing effects to interactions.
Academic Article Is the Risk Difference Really a More Heterogeneous Measure?
Academic Article Molecular pathological epidemiology gives clues to paradoxical findings.
Academic Article Review Article: The Role of Molecular Pathological Epidemiology in the Study of Neoplastic and Non-neoplastic Diseases in the Era of Precision Medicine.
Academic Article Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis.
Academic Article Sensitivity Analysis Without Assumptions.
Academic Article The Authors Respond.
Academic Article Sufficient Cause Representation of the Four-way Decomposition for Mediation and Interaction.
Academic Article Brief Report: Mediation Analysis with an Ordinal Outcome.
Grant Theory and methods for sufficient cause interactions
Grant Bounds for direct and indirect effects with application to perinatal epidemiology
Academic Article Parametric Mediational g-Formula Approach to Mediation Analysis with Time-varying Exposures, Mediators, and Confounders.
Academic Article Proceedings of the third international molecular pathological epidemiology (MPE) meeting.
Academic Article Outcome-wide Epidemiology.
Academic Article Re: Causality and causal inference in epidemiology: the need for a pluralistic approach.
Academic Article On a Square-Root Transformation of the Odds Ratio for a Common Outcome.
Academic Article R Function for Additive Interaction Measures.
Academic Article Utility of inverse probability weighting in molecular pathological epidemiology.
Academic Article Absolute risks of obstetric outcomes by maternal age at first birth: a population-based cohort.
Academic Article On Well-defined Hypothetical Interventions in the Potential Outcomes Framework.
Academic Article Web Site and R Package for Computing E-values.
Academic Article Decomposition Analysis to Identify Intervention Targets for Reducing Disparities.
Academic Article Selecting Optimal Subgroups for Treatment Using Many Covariates.
Academic Article Multiplicative Interactions Under Differential Outcome Measurement Error with Perfect Specificity.
Academic Article Bounding Bias Due to Selection.
Academic Article The Interaction Continuum.
Academic Article Mediational E-values: Approximate Sensitivity Analysis for Unmeasured Mediator-Outcome Confounding.
Academic Article Invited Commentary: Counterfactuals in Social Epidemiology-Thinking Outside of "the Box".
Academic Article A Simple, Interpretable Conversion from Pearson's Correlation to Cohen's for d Continuous Exposures.
Academic Article Positive Epidemiology?
Academic Article The Authors Respond.
Academic Article E-Values for Mendelian Randomization.
Academic Article Robust Metrics and Sensitivity Analyses for Meta-analyses of Heterogeneous Effects.
Academic Article The Authors Respond.
Academic Article Simple Sensitivity Analysis for Control Selection Bias.
Academic Article The Authors Respond.
Academic Article E Values and Incidence Density Sampling.
Academic Article CMAverse: A Suite of Functions for Reproducible Causal Mediation Analyses.
Academic Article Multiple-bias Sensitivity Analysis Using Bounds.
Academic Article Constructed measures and causal inference: towards a new model of measurement for psychosocial constructs.
Academic Article Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration.
Academic Article Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement.
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  • Epidemiology
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.