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One or more keywords matched the following properties of Kirsch, Irving
overview Irving Kirsch is Associate Director of the Program in Placebo Studies and lecturer in medicine at the Harvard Medical School and Beth Israel Deaconess Medical Center. He is also Professor Emeritus of Psychology at the University of Plymouth (UK), and University of Hull (UK), and University of Connecticut (US). He has published 10 books and more than 250 scientific journal articles and book chapters on placebo effects, antidepressant medication, hypnosis, and suggestion. He originated the concept of response expectancy. His meta-analyses on the efficacy of antidepressants were covered extensively in the international media and influenced official guidelines for the treatment of depression in the United Kingdom. His book, The Emperor’s New Drugs: Exploding the Antidepressant Myth, which has been published in English, French, Japanese, Italian, Turkish, and Polish, was shortlisted for the prestigious Mind Book of the Year award. It was the topic of 60 Minutes segment on CBS and a 5-page cover story in Newsweek.
One or more keywords matched the following items that are connected to Kirsch, Irving
Item TypeName
Academic Article Clinical trials and the response rate illusion.
Academic Article A systematic review of comparative efficacy of treatments and controls for depression.
Academic Article Antidepressants and the placebo response.
Academic Article Review: benefits of antidepressants over placebo limited except in very severe depression.
Academic Article Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration.
Academic Article Antidepressant drugs 'work', but they are not clinically effective.
Academic Article Efficacy of antidepressants in adults.
Academic Article Suggestion in the treatment of depression.
Academic Article Moving beyond depression: How full is the glass?
Academic Article Challenging received wisdom: antidepressants and the placebo effect.
Academic Article Kirsch et al.'s (2008) calculations are correct: reconsidering Fountoulakis & Möller's re-analysis of the Kirsch data.
Concept Antidepressive Agents
Concept Antidepressive Agents, Second-Generation
Concept Antidepressive Agents, Tricyclic
Academic Article The efficacy of paroxetine and placebo in treating anxiety and depression: a meta-analysis of change on the Hamilton Rating Scales.
Academic Article Moderation of antidepressant and placebo outcomes by baseline severity in late-life depression: A systematic review and meta-analysis.
Academic Article Drug approval and drug effectiveness.
Academic Article Empirically derived criteria cast doubt on the clinical significance of antidepressant-placebo differences.
Academic Article Patient Expectancy as a Mediator of Placebo Effects in Antidepressant Clinical Trials.
Academic Article Antidepressants and the Placebo Effect.
Academic Article Obsessive-compulsive disorder has a reduced placebo (and antidepressant) response compared to other anxiety disorders: A meta-analysis.
Academic Article Response Expectancy and the Response to Antidepressant Medication.
Academic Article Network meta-analysis of antidepressants.
Academic Article Should antidepressants be used for major depressive disorder?
Academic Article Re: "The Impact of Placebo Response Rates on Clinical Trial Outcome: A Systematic Review and Meta-Analysis of Antidepressants in Children and Adolescents with Major Depressive Disorder" by Li Y, Huang J, He Y, Yang J, Lv Y, Liu H, Liang L, Zheng Q, and Li L (J Child Adolesc Psychopharmacol 29:712-720, 2019).
Academic Article Open-Label placebo for the treatment of unipolar depression: Results from a randomized controlled trial.
Academic Article Beneficial and harmful effects of antidepressants versus placebo, 'active placebo', or no intervention for adults with major depressive disorder: a protocol for a systematic review of published and unpublished data with meta-analyses and trial sequential analyses.
Academic Article Tricyclic antidepressants versus 'active placebo', placebo or no intervention for adults with major depressive disorder: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis.
Search Criteria
  • Antidepressive Agents
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.