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One or more keywords matched the following items that are connected to Rapoport, Tom
Item TypeName
Academic Article Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes.
Academic Article Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.
Academic Article Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.
Academic Article Posttranslational protein transport into the endoplasmic reticulum.
Academic Article Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol.
Academic Article The identification of proteins in the proximity of signal-anchor sequences during their targeting to and insertion into the membrane of the ER.
Academic Article Protein translocation by the Sec61/SecY channel.
Academic Article Components and mechanism of protein translocation across the ER membrane.
Academic Article Interaction of BiP with the J-domain of the Sec63p component of the endoplasmic reticulum protein translocation complex.
Academic Article The beta subunit of the Sec61 complex facilitates cotranslational protein transport and interacts with the signal peptidase during translocation.
Academic Article Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae.
Academic Article The structure of ribosome-channel complexes engaged in protein translocation.
Academic Article A class of membrane proteins shaping the tubular endoplasmic reticulum.
Academic Article Rough sheets and smooth tubules.
Academic Article Protein transport by purified yeast Sec complex and Kar2p without membranes.
Academic Article Posttranslational protein translocation across the membrane of the endoplasmic reticulum.
Academic Article Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin.
Academic Article Binding of signal recognition particle gives ribosome/nascent chain complexes a competitive advantage in endoplasmic reticulum membrane interaction.
Academic Article A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein.
Academic Article Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance.
Academic Article A signal sequence receptor in the endoplasmic reticulum membrane.
Academic Article Protein transport across the ER membrane.
Academic Article TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum.
Academic Article Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm.
Academic Article A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation.
Academic Article BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane.
Academic Article In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction.
Academic Article Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulum.
Academic Article The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.
Academic Article Retro-translocation of proteins from the endoplasmic reticulum into the cytosol.
Academic Article Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons.
Academic Article Segregation of the signal sequence receptor protein in the rough endoplasmic reticulum membrane.
Academic Article Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate.
Academic Article Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.
Academic Article The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p.
Academic Article Protein translocation: tunnel vision.
Academic Article The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum.
Academic Article Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane.
Academic Article Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane.
Academic Article Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane.
Academic Article Regulation by the ribosome of the GTPase of the signal-recognition particle during protein targeting.
Academic Article Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
Academic Article A membrane component of the endoplasmic reticulum that may be essential for protein translocation.
Academic Article The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae.
Academic Article Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.
Academic Article The endoplasmic reticulum membrane is permeable to small molecules.
Academic Article Structure and biosynthesis of the signal-sequence receptor.
Academic Article The signal sequence receptor has a second subunit and is part of a translocation complex in the endoplasmic reticulum as probed by bifunctional reagents.
Academic Article Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum.
Academic Article Structural organization of the endoplasmic reticulum.
Academic Article Processing and turnover of the Hedgehog protein in the endoplasmic reticulum.
Academic Article Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes.
Academic Article A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.
Academic Article The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate.
Academic Article Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains.
Academic Article Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking.
Academic Article A novel pathway for secretory proteins?
Academic Article Membrane proteins of the endoplasmic reticulum induce high-curvature tubules.
Academic Article Translocation of proteins through the endoplasmic reticulum membrane: investigation of their molecular environment by cross-linking
Academic Article Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners.
Academic Article Demonstration of specific receptors of the rough endoplasmic membrane for the signal sequence of carp preproinsulin.
Academic Article A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane.
Academic Article Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion.
Academic Article A protein of the endoplasmic reticulum involved early in polypeptide translocation.
Academic Article Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane.
Academic Article A receptor for single segments of secretory proteins in rough endoplasmic reticulum membranes.
Academic Article Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA.
Academic Article Ratcheting in post-translational protein translocation: a mathematical model.
Academic Article Protein transport across the endoplasmic reticulum membrane: facts, models, mysteries.
Academic Article Generation of nonidentical compartments in vesicular transport systems.
Academic Article Signal sequence recognition in posttranslational protein transport across the yeast ER membrane.
Academic Article Yeast Sec proteins interact with polypeptides traversing the endoplasmic reticulum membrane.
Academic Article A tetrameric complex of membrane proteins in the endoplasmic reticulum.
Academic Article Protein transport across the endoplasmic reticulum membrane.
Academic Article A class of dynamin-like GTPases involved in the generation of the tubular ER network.
Academic Article Structure of the mammalian ribosome-channel complex at 17A resolution.
Academic Article Architecture of the ribosome-channel complex derived from native membranes.
Academic Article Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1.
Academic Article Signal recognition in protein translocation across the endoplasmic reticulum membrane.
Academic Article Ribosome binding to and dissociation from translocation sites of the endoplasmic reticulum membrane.
Academic Article Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome.
Academic Article The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum.
Academic Article Protein transport in and out of the endoplasmic reticulum.
Academic Article Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane.
Academic Article Signal recognition particle triggers the translocation of storage globulin polypeptides from field beans (Vicia faba L.) across mammalian endoplasmic reticulum membrane.
Academic Article Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence.
Academic Article DIDS (4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid) inhibits an early step of protein translocation across the mammalian ER membrane.
Academic Article Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion.
Academic Article Predicting the orientation of eukaryotic membrane-spanning proteins.
Academic Article Photocrosslinking demonstrates proximity of a 34 kDa membrane protein to different portions of preprolactin during translocation through the endoplasmic reticulum.
Academic Article Different modes of membrane interactions of the signal sequence of carp preproinsulin and of the insertion sequence of rabbit cytochrome b5.
Academic Article Molecular mechanism of membrane protein integration into the endoplasmic reticulum.
Academic Article Signal sequence recognition in cotranslational translocation by protein components of the endoplasmic reticulum membrane.
Academic Article Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane.
Academic Article Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane.
Academic Article A signal sequence is required for the functions of the signal recognition particle.
Academic Article Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex.
Academic Article A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae.
Academic Article Protein translocation across and integration into membranes.
Academic Article Protein translocation: common themes from bacteria to man.
Academic Article Approaching the mechanism of protein transport across the ER membrane.
Academic Article Transport of proteins across the endoplasmic reticulum membrane.
Academic Article Protein folding taking shape. Workshop on molecular chaperones.
Academic Article Gangliosides are receptors for murine polyoma virus and SV40.
Academic Article Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane.
Academic Article A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane.
Concept Endoplasmic Reticulum, Rough
Concept Endoplasmic Reticulum, Smooth
Concept Endoplasmic Reticulum
Academic Article A conserved role for atlastin GTPases in regulating lipid droplet size.
Academic Article Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs.
Academic Article Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts.
Academic Article An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER.
Academic Article Key steps in ERAD of luminal ER proteins reconstituted with purified components.
Academic Article A model for the generation and interconversion of ER morphologies.
Academic Article Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
Academic Article Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy.
Academic Article Involvement of VAT-1 in Phosphatidylserine Transfer from the Endoplasmic Reticulum to Mitochondria.
Academic Article Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.
Grant Protein Transport Across Membranes
Grant POSTTRANSLATIONAL PROTEIN TRANSPORT INTO YEAST ER
Academic Article Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.
Academic Article Fusion of the endoplasmic reticulum by membrane-bound GTPases.
Academic Article Reconstitution of the tubular endoplasmic reticulum network with purified components.
Academic Article Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Academic Article Endoplasmic Reticulum Network Formation with Xenopus Egg Extracts.
Academic Article Mechanistic insights into ER-associated protein degradation.
Academic Article Structure of the post-translational protein translocation machinery of the ER membrane.
Academic Article Reconstituting the reticular ER network - mechanistic implications and open questions.
Academic Article Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.
Academic Article Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Academic Article Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Academic Article Mechanism of membrane-curvature generation by ER-tubule shaping proteins.
Search Criteria
  • Endoplasmic Reticulum
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.