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One or more keywords matched the following items that are connected to Neumeyer, John
Item TypeName
Academic Article Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse.
Academic Article New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores.
Academic Article 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols.
Academic Article An investigation of the N-demethylation of 3-deoxymorphine and the affinity of the alkylation products to mu, delta, and kappa receptors.
Academic Article Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan.
Academic Article Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence.
Academic Article Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.
Academic Article 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors.
Academic Article Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors.
Academic Article Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors.
Academic Article Effects of mixed-action kappa/mu opioids on cocaine self-administration and cocaine discrimination by rhesus monkeys.
Academic Article Kappa receptor bivalent ligands.
Academic Article Aminothiazolomorphinans with mixed ? and µ opioid activity.
Academic Article In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties.
Academic Article Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.
Academic Article Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior.
Academic Article Antidepressant-like effects of the novel kappa opioid antagonist MCL-144B in the forced-swim test.
Academic Article Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.
Academic Article High-affinity carbamate analogues of morphinan at opioid receptors.
Academic Article Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.
Academic Article Effects of ATPM-ET, a novel ? agonist with partial µ activity, on physical dependence and behavior sensitization in mice.
Academic Article Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for ?, µ, and d opioid receptors.
Concept Receptors, Opioid, kappa
Academic Article Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors.
Academic Article Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with ? agonist and µ agonist/antagonist activity.
Grant Mixed Kappa-Mu Opioids: Synthesis and Evaluation
Search Criteria
  • Receptors Opioid kappa
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.