Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Drazen, Jeffrey
Item TypeName
Academic Article Should antileukotriene therapies be used instead of inhaled corticosteroids in asthma? Yes.
Academic Article Urinary leukotriene E4 levels increase upon exposure to hypobaric hypoxia.
Academic Article Heterogeneity of therapeutic responses in asthma.
Academic Article Recurrent panniculitis in a man with asthma receiving treatment with leukotriene-modifying agents.
Academic Article The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Academic Article Antileukotrienes in the treatment of asthma.
Academic Article Urinary leukotriene (LT) E(4) in adolescents with dysmenorrhea: a pilot study.
Academic Article Leukotriene receptor on U-937 cells: discriminatory responses to leukotrienes C4 and D4.
Academic Article New directions in asthma drug therapy.
Academic Article Changes in cross-sectional airway areas induced by methacholine, histamine, and LTC4 in asthmatic subjects.
Academic Article The effects of a fish-oil-enriched diet on pulmonary mechanics during anaphylaxis.
Academic Article Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors.
Academic Article Treatment of asthma with drugs modifying the leukotriene pathway.
Academic Article The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms.
Academic Article Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma.
Academic Article Anti-leukotrienes as novel anti-inflammatory treatments in asthma.
Academic Article Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast.
Academic Article Functional characterization of synthetic leukotriene B and its stereochemical isomers.
Academic Article Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins.
Academic Article Biology of the C-6-sulfidopeptide leukotrienes.
Academic Article Effects of leukotriene D on the airways in asthma.
Academic Article Asthma therapy with agents preventing leukotriene synthesis or action.
Academic Article Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects.
Academic Article Effects of indomethacin on the guinea-pig pulmonary response to intravenous leukotrienes C4 and D4.
Academic Article Clinical Decisions. Mild persistent asthma--polling results.
Academic Article Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
Academic Article Inhalation challenge with sulfidopeptide leukotrienes in human subjects.
Academic Article Cytogenetic and radiation hybrid mapping of human arachidonate 5-lipoxygenase-activating protein (ALOX5AP) to chromosome 13q12.
Academic Article The pharmacogenetics of asthma: a candidate gene approach.
Academic Article Pharmacogenetics of asthma.
Academic Article LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter.
Academic Article A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha.
Academic Article Leukotriene E4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide leukotriene receptors.
Academic Article Contractile activities of structural analogs of leukotrienes C and D: role of the polar substituents.
Academic Article A review of recent contributions on biologically active products of arachidonate conversion.
Academic Article Asthma treatment guidelines meet the real world.
Academic Article Differential effects of calcium channel blockers on leukotriene C4- and D4-induced contractions in guinea pig pulmonary parenchymal strips.
Academic Article A formyl peptide contracts guinea pig lung: role of arachidonic acid metabolites.
Academic Article Bronchoconstrictor effects of leukotriene C in humans.
Academic Article International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions.
Academic Article Airway constriction in normal humans produced by inhalation of leukotriene D. Potency, time course, and effect of aspirin therapy.
Academic Article Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma.
Academic Article Effects of leukotriene E on pulmonary mechanics in the guinea pig.
Academic Article Role of cysteinyl leukotrienes in spontaneous asthmatic responses.
Academic Article Pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors in the management of asthma.
Academic Article Leukotrienes in asthma.
Academic Article Heterogeneity of leukotriene C4 production by eosinophils from asthmatic and from normal subjects.
Academic Article Leukotrienes and immediate hypersensitivity responses.
Academic Article Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity.
Academic Article Immunologically induced generation of tetraene and pentaene leukotrienes in the peritoneal cavities of menhaden-fed rats.
Academic Article Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
Academic Article Slow reacting substances of anaphylaxis: identification of leukotrienes C-1 and D from human and rat sources.
Academic Article The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma.
Academic Article Recovery of leukotriene E4 from the urine of patients with airway obstruction.
Academic Article Pharmacogenetics of the 5-lipoxygenase pathway in asthma.
Academic Article The effect of indomethacin on the contractile response of the guinea-pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4.
Academic Article International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors.
Academic Article Asthma: a solution to half the puzzle?
Academic Article Airway luminal liquid. Sources and role as an amplifier of bronchoconstriction.
Academic Article Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?
Academic Article 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States.
Academic Article Genetics and pharmacogenetics of the leukotriene pathway.
Academic Article Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects.
Academic Article Differential responses of tissue viscance and collateral resistance to histamine and leukotriene C4.
Academic Article The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin.
Academic Article Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteers.
Academic Article Diurnal variation of urinary leukotriene E4 and histamine excretion rates in normal subjects and patients with mild-to-moderate asthma.
Academic Article Clinical studies with agents active on the 5-lipoxygenase pathway.
Academic Article Substrate and regulatory functions of eicosapentaenoic and docosahexaenoic acids for the 5-lipoxygenase pathway. Implications for pulmonary responses.
Academic Article Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects.
Academic Article Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature.
Academic Article Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics.
Academic Article Leukotrienes and airway responses.
Academic Article Indomethacin potentiates the pulmonary response to aerosol leukotriene C4 in the guinea pig.
Academic Article Contractile activities of structural analogs of leukotrienes C and D: necessity of a hydrophobic region.
Academic Article Leukotrienes as mediators of airway obstruction.
Academic Article Chemical regulation of pulmonary airway tone.
Academic Article Structure, function, and metabolism of leukotriene constituents of SRS-A.
Academic Article Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro.
Concept Leukotriene A4
Concept Leukotriene C4
Concept Leukotriene E4
Concept Leukotriene B4
Concept Leukotriene Antagonists
Concept Leukotriene D4
Concept Leukotrienes
Concept Receptors, Leukotriene
Academic Article Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7.
Grant Chemical Mediators of Acute Pulmonary Disorders
Search Criteria
  • Leukotriene C4
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.