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One or more keywords matched the following items that are connected to Huang, Xudong
Item TypeName
Academic Article The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction.
Academic Article Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.
Academic Article Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides.
Academic Article Copper catalyzed oxidation of Alzheimer Abeta.
Academic Article Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
Academic Article Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.
Academic Article Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.
Academic Article Metal chelation as a potential therapy for Alzheimer's disease.
Academic Article Mounting evidence for the involvement of zinc and copper in Alzheimer's disease.
Academic Article Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.
Academic Article Iron inhibits neurotoxicity induced by trace copper and biological reductants.
Academic Article Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Academic Article Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.
Academic Article Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.
Academic Article Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations.
Academic Article Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.
Academic Article 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction.
Academic Article Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).
Concept Copper
Academic Article Metal Ions and Neurodegenerative Disorders (Zatta P, editor)
Academic Article High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles.
Grant ZINC AND ALZHEIMERS AMYLOID CHEMISTRY
Academic Article Exposure of CuO Nanoparticles Contributes to Cellular Apoptosis, Redox Stress, and Alzheimer's Aß Amyloidosis.
Academic Article A Preliminary Study of Cu Exposure Effects upon Alzheimer's Amyloid Pathology.
Search Criteria
  • Copper
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.