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One or more keywords matched the following items that are connected to Struhl, Kevin
Item TypeName
Academic Article Yeast transcriptional regulatory mechanisms.
Academic Article A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo.
Academic Article TBP-associated factors are not generally required for transcriptional activation in yeast.
Academic Article Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo.
Academic Article Incorporation of Drosophila TAF110 into the yeast TFIID complex does not permit the Sp1 glutamine-rich activation domain to function in vivo.
Academic Article The TAFs in the HAT.
Academic Article Heterochromatin formation involves changes in histone modifications over multiple cell generations.
Academic Article Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast.
Academic Article Histone acetylation and transcriptional regulatory mechanisms.
Academic Article Activation and repression mechanisms in yeast.
Academic Article Artificial recruitment of TFIID, but not RNA polymerase II holoenzyme, activates transcription in mammalian cells.
Academic Article Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains.
Academic Article Transcriptional noise and the fidelity of initiation by RNA polymerase II.
Academic Article Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters.
Academic Article A TATA-binding protein mutant defective for TFIID complex formation in vivo.
Academic Article Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress.
Academic Article Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation.
Academic Article Genomic analysis of protein-DNA interactions in bacteria: insights into transcription and chromosome organization.
Academic Article The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.
Academic Article TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivo.
Academic Article Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae.
Academic Article Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast.
Academic Article Analysis of Saccharomyces cerevisiae his3 transcription in vitro: biochemical support for multiple mechanisms of transcription.
Academic Article Functional differences between yeast and human TFIID are localized to the highly conserved region.
Academic Article Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae.
Academic Article Role of the conserved leucines in the leucine zipper dimerization motif of yeast GCN4.
Academic Article TREX is a conserved complex coupling transcription with messenger RNA export.
Academic Article Fundamentally different logic of gene regulation in eukaryotes and prokaryotes.
Academic Article Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase.
Academic Article Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription.
Academic Article MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction.
Academic Article The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes.
Academic Article The histone H3-like TAF is broadly required for transcription in yeast.
Academic Article Synthesizing proteins in vitro by transcription and translation of cloned genes.
Academic Article Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo.
Academic Article Synergistic transcriptional enhancement does not depend on the number of acidic activation domains bound to the promoter.
Academic Article Reverse biochemistry: methods and applications for synthesizing yeast proteins in vitro.
Academic Article Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure.
Academic Article A wide variety of DNA sequences can functionally replace a yeast TATA element for transcriptional activation.
Academic Article The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein.
Academic Article ACR1, a yeast ATF/CREB repressor.
Academic Article SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
Academic Article Functional distinctions between yeast TATA elements.
Academic Article Duality of TBP, the universal transcription factor.
Academic Article TFIIA has activator-dependent and core promoter functions in vivo.
Academic Article Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation.
Academic Article The leucine zipper symmetrically positions the adjacent basic regions for specific DNA binding.
Academic Article An HMG protein, Hmo1, associates with promoters of many ribosomal protein genes and throughout the rRNA gene locus in Saccharomyces cerevisiae.
Academic Article Molecular mechanisms of transcriptional regulation in yeast.
Academic Article Yeast mRNA initiation sites are determined primarily by specific sequences, not by the distance from the TATA element.
Academic Article Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters.
Academic Article Yeast NC2 associates with the RNA polymerase II preinitiation complex and selectively affects transcription in vivo.
Academic Article Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors.
Academic Article TFIIS enhances transcriptional elongation through an artificial arrest site in vivo.
Academic Article Extensive functional overlap between sigma factors in Escherichia coli.
Academic Article Tc, an unusual promoter element required for constitutive transcription of the yeast HIS3 gene.
Academic Article A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Academic Article Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange.
Academic Article Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II.
Academic Article Mechanisms of transcriptional activation in vivo: two steps forward.
Academic Article Constitutive and coordinately regulated transcription of yeast genes: promoter elements, positive and negative regulatory sites, and DNA binding proteins.
Academic Article Transcription of the his3 gene region in Saccharomyces cerevisiae.
Academic Article The yeast his3 promoter contains at least two distinct elements.
Academic Article Differential analysis for high density tiling microarray data.
Academic Article Close association of RNA polymerase II and many transcription factors with Pol III genes.
Academic Article An integrated encyclopedia of DNA elements in the human genome.
Academic Article The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast.
Academic Article Chromatin structure and RNA polymerase II connection: implications for transcription.
Academic Article Helix-turn-helix, zinc-finger, and leucine-zipper motifs for eukaryotic transcriptional regulatory proteins.
Academic Article A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.
Academic Article Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.
Academic Article A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element.
Academic Article Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex.
Academic Article Two related regulatory sequences are required for maximal induction of Saccharomyces cerevisiae his3 transcription.
Academic Article Yeast and human TFIIDs are interchangeable for the response to acidic transcriptional activators in vitro.
Academic Article Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation.
Academic Article Nucleotide sequence and transcriptional mapping of the yeast pet56-his3-ded1 gene region.
Academic Article Molecular characterization of GCD1, a yeast gene required for general control of amino acid biosynthesis and cell-cycle initiation.
Academic Article Promoter elements, regulatory elements, and chromatin structure of the yeast his3 gene.
Academic Article A physiological study of functional expression in Escherichia coli of the cloned yeast imidazoleglycerolphosphate dehydratase gene.
Academic Article Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity.
Academic Article The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells.
Academic Article Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex.
Academic Article A physical, genetic and transcriptional map of the cloned his3 gene region of Saccharomyces cerevisiae.
Academic Article Mechanism of differential utilization of the his3 TR and TC TATA elements.
Academic Article Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element.
Academic Article The gradient morphogen bicoid is a concentration-dependent transcriptional activator.
Academic Article Negative control at a distance mediates catabolite repression in yeast.
Academic Article Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast.
Academic Article Conserved and nonconserved functions of the yeast and human TATA-binding proteins.
Academic Article CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters.
Academic Article Targeted recruitment of Rpd3 histone deacetylase represses transcription by inhibiting recruitment of Swi/Snf, SAGA, and TATA binding protein.
Academic Article The VP16 activation domain interacts with multiple transcriptional components as determined by protein-protein cross-linking in vivo.
Academic Article Mechanisms for diversity in gene expression patterns.
Academic Article Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro.
Academic Article Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.
Academic Article The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae.
Academic Article Regional codon randomization: defining a TATA-binding protein surface required for RNA polymerase III transcription.
Academic Article The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting.
Academic Article GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.
Academic Article Absolute mRNA levels and transcriptional initiation rates in Saccharomyces cerevisiae.
Academic Article Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein.
Academic Article Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo.
Academic Article Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity.
Academic Article SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers.
Academic Article Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast.
Academic Article Saturation mutagenesis of the yeast his3 regulatory site: requirements for transcriptional induction and for binding by GCN4 activator protein.
Academic Article Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase.
Academic Article Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms.
Academic Article Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.
Academic Article Association of RNA polymerase with transcribed regions in Escherichia coli.
Academic Article Activator-specific recruitment of Mediator in vivo.
Academic Article Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo.
Academic Article NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.
Academic Article Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3'-end formation.
Academic Article The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals.
Academic Article The FACT complex travels with elongating RNA polymerase II and is important for the fidelity of transcriptional initiation in vivo.
Academic Article Yeast HIS3 expression in Escherichia coli depends upon fortuitous homology between eukaryotic and prokaryotic promoter elements.
Academic Article Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Academic Article Genetic properties and chromatin structure of the yeast gal regulatory element: an enhancer-like sequence.
Academic Article Eaf3 regulates the global pattern of histone acetylation in Saccharomyces cerevisiae.
Academic Article Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells.
Academic Article Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites.
Concept Transcription, Genetic
Academic Article Is DNA methylation of tumour suppressor genes epigenetic?
Academic Article Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo.
Academic Article The Ground State and Evolution of Promoter Region Directionality.
Search Criteria
  • Transcription Genetic