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One or more keywords matched the following items that are connected to Struhl, Kevin
Item TypeName
Academic Article TBP-associated factors are not generally required for transcriptional activation in yeast.
Academic Article The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast.
Academic Article Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo.
Academic Article Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes.
Academic Article Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme.
Academic Article The TAFs in the HAT.
Academic Article Region of yeast TAF 130 required for TFIID to associate with promoters.
Academic Article Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast.
Academic Article Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast.
Academic Article Histone acetylation and transcriptional regulatory mechanisms.
Academic Article Uracil interference, a rapid and general method for defining protein-DNA interactions involving the 5-methyl group of thymines: the GCN4-DNA complex.
Academic Article Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters.
Academic Article Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains.
Academic Article Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress.
Academic Article Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation.
Academic Article Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79.
Academic Article The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.
Academic Article Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association.
Academic Article Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae.
Academic Article Analysis of Saccharomyces cerevisiae his3 transcription in vitro: biochemical support for multiple mechanisms of transcription.
Academic Article Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae.
Academic Article Analysis of protein co-occupancy by quantitative sequential chromatin immunoprecipitation.
Academic Article Role of the conserved leucines in the leucine zipper dimerization motif of yeast GCN4.
Academic Article TREX is a conserved complex coupling transcription with messenger RNA export.
Academic Article Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase.
Academic Article Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription.
Academic Article MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction.
Academic Article The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes.
Academic Article The histone H3-like TAF is broadly required for transcription in yeast.
Academic Article Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo.
Academic Article Synergistic transcriptional enhancement does not depend on the number of acidic activation domains bound to the promoter.
Academic Article Histone acetylation at promoters is differentially affected by specific activators and repressors.
Academic Article Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein.
Academic Article Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure.
Academic Article The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein.
Academic Article ACR1, a yeast ATF/CREB repressor.
Academic Article Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress.
Academic Article Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast.
Academic Article TFIIA has activator-dependent and core promoter functions in vivo.
Academic Article Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation.
Academic Article TAF-Containing and TAF-independent forms of transcriptionally active TBP in vivo.
Academic Article The leucine zipper symmetrically positions the adjacent basic regions for specific DNA binding.
Academic Article An HMG protein, Hmo1, associates with promoters of many ribosomal protein genes and throughout the rRNA gene locus in Saccharomyces cerevisiae.
Academic Article Genome-wide location analysis of the stress-activated MAP kinase Hog1 in yeast.
Academic Article Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters.
Academic Article Yeast NC2 associates with the RNA polymerase II preinitiation complex and selectively affects transcription in vivo.
Academic Article Genome-wide occupancy profile of the RNA polymerase III machinery in Saccharomyces cerevisiae reveals loci with incomplete transcription complexes.
Academic Article A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Academic Article Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast.
Academic Article A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Academic Article Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange.
Academic Article Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II.
Academic Article Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.
Academic Article A functional evolutionary approach to identify determinants of nucleosome positioning: a unifying model for establishing the genome-wide pattern.
Academic Article The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast.
Academic Article Transcriptional activation by yeast GCN4, a functional homolog to the jun oncoprotein.
Academic Article A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element.
Academic Article The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo.
Academic Article GCN4 protein, synthesized in vitro, binds HIS3 regulatory sequences: implications for general control of amino acid biosynthetic genes in yeast.
Academic Article Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo.
Academic Article Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex.
Academic Article Yeast and human TFIIDs are interchangeable for the response to acidic transcriptional activators in vitro.
Academic Article Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.
Academic Article Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity.
Academic Article Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex.
Academic Article Cellular stress alters the transcriptional properties of promoter-bound Mot1-TBP complexes.
Academic Article Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae.
Academic Article Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element.
Academic Article Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA.
Academic Article The TBP-TFIIA interaction in the response to acidic activators in vivo.
Academic Article CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters.
Academic Article Targeted recruitment of Rpd3 histone deacetylase represses transcription by inhibiting recruitment of Swi/Snf, SAGA, and TATA binding protein.
Academic Article The VP16 activation domain interacts with multiple transcriptional components as determined by protein-protein cross-linking in vivo.
Academic Article Transcriptional activation in yeast cells lacking transcription factor IIA.
Academic Article Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes.
Academic Article The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous.
Academic Article The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae.
Academic Article Dimerization of leucine zippers analyzed by random selection.
Academic Article GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.
Academic Article Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo.
Academic Article Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein.
Academic Article Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo.
Academic Article Saturation mutagenesis of the yeast his3 regulatory site: requirements for transcriptional induction and for binding by GCN4 activator protein.
Academic Article Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase.
Academic Article Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.
Academic Article Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo.
Academic Article NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.
Academic Article Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.
Academic Article The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals.
Academic Article The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex.
Academic Article The FACT complex travels with elongating RNA polymerase II and is important for the fidelity of transcriptional initiation in vivo.
Academic Article The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress.
Academic Article Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo.
Academic Article Preferential accessibility of the yeast his3 promoter is determined by a general property of the DNA sequence, not by specific elements.
Academic Article Mutations in the bZIP domain of yeast GCN4 that alter DNA-binding specificity.
Academic Article Eaf3 regulates the global pattern of histone acetylation in Saccharomyces cerevisiae.
Academic Article Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites.
Concept Saccharomyces cerevisiae Proteins
Academic Article Mediator Undergoes a Compositional Change during Transcriptional Activation.
Academic Article Extensive Structural Differences of Closely Related 3' mRNA Isoforms: Links to Pab1 Binding and mRNA Stability.
Academic Article The transcriptional elongation rate regulates alternative polyadenylation in yeast.
Academic Article Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species.
Search Criteria
  • Saccharomyces cerevisiae Proteins
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.