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One or more keywords matched the following items that are connected to Lander, Eric
Item TypeName
Academic Article A locus for Fanconi anemia on 16q determined by homozygosity mapping.
Academic Article Genome maps 7. The human transcript map. Wall chart.
Academic Article The new genomics: global views of biology.
Academic Article Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families.
Academic Article A gene map of the human genome.
Academic Article A comprehensive large-insert yeast artificial chromosome library for physical mapping of the mouse genome.
Academic Article A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.
Academic Article A genetic map of the mouse suitable for typing intraspecific crosses.
Academic Article Genes and genomes.
Academic Article Sequencing and comparison of yeast species to identify genes and regulatory elements.
Academic Article Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts.
Academic Article Analysis of the DNA sequence and duplication history of human chromosome 15.
Academic Article Radiation hybrid map of the mouse genome.
Academic Article An SNP map of the human genome generated by reduced representation shotgun sequencing.
Academic Article More on the sequencing of the human genome.
Academic Article The genome sequence of the filamentous fungus Neurospora crassa.
Academic Article An integrated haplotype map of the human major histocompatibility complex.
Academic Article The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression.
Academic Article Remodeling of yeast genome expression in response to environmental changes.
Academic Article A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms.
Academic Article The structure of haplotype blocks in the human genome.
Academic Article Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.
Academic Article Sequencing the nuclear genome of the extinct woolly mammoth.
Academic Article The mosaic structure of variation in the laboratory mouse genome.
Academic Article BB rat diabetes susceptibility and body weight regulation genes colocalize on chromosome 2.
Academic Article Position specific variation in the rate of evolution in transcription factor binding sites.
Academic Article Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat.
Academic Article A genome-wide map of diversity in Plasmodium falciparum.
Academic Article Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease.
Academic Article Using a genome-wide scan and meta-analysis to identify a novel IBD locus and confirm previously identified IBD loci.
Academic Article Transcriptional regulatory code of a eukaryotic genome.
Academic Article Array of hope.
Academic Article The 1.4-Mb CMT1A duplication/HNPP deletion genomic region reveals unique genome architectural features and provides insights into the recent evolution of new genes.
Academic Article Absolute quantification of somatic DNA alterations in human cancer.
Academic Article Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.
Academic Article Comment on "The consensus coding sequences of human breast and colorectal cancers".
Academic Article Efficient mapping of mendelian traits in dogs through genome-wide association.
Academic Article Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution.
Academic Article Sequencing a genome by walking with clone-end sequences: a mathematical analysis.
Academic Article ARACHNE: a whole-genome shotgun assembler.
Academic Article An automated method for DNA preparation from thousands of YAC clones.
Academic Article Initial sequencing and analysis of the human genome.
Academic Article Construction of a large-insert yeast artificial chromosome library of the rat genome.
Academic Article A physical map of 30,000 human genes.
Academic Article Identification and classification of conserved RNA secondary structures in the human genome.
Academic Article Hi-C: a method to study the three-dimensional architecture of genomes.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Characterizing the cancer genome in lung adenocarcinoma.
Academic Article Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
Academic Article Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.
Academic Article Genome-scale loss-of-function screening with a lentiviral RNAi library.
Academic Article Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.
Academic Article Distinguishing protein-coding and noncoding genes in the human genome.
Academic Article Genomics: journey to the center of biology.
Academic Article Human genome sequence variation and the influence of gene history, mutation and recombination.
Academic Article Genetic evidence for complex speciation of humans and chimpanzees.
Academic Article 28-way vertebrate alignment and conservation track in the UCSC Genome Browser.
Academic Article ALLPATHS: de novo assembly of whole-genome shotgun microreads.
Academic Article A composite of multiple signals distinguishes causal variants in regions of positive selection.
Academic Article Risk alleles for multiple sclerosis identified by a genomewide study.
Academic Article New models of collaboration in genome-wide association studies: the Genetic Association Information Network.
Academic Article The genomic basis of adaptive evolution in threespine sticklebacks.
Academic Article Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability.
Academic Article Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome.
Academic Article A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population.
Academic Article Whole-genome sequence assembly for mammalian genomes: Arachne 2.
Academic Article Genetic map of rat chromosome 5 including the fatty (fa) locus.
Academic Article An STS-based map of the human genome.
Academic Article A family of conserved noncoding elements derived from an ancient transposable element.
Academic Article The genome of M. acetivorans reveals extensive metabolic and physiological diversity.
Academic Article Detecting recent positive selection in the human genome from haplotype structure.
Academic Article Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery.
Academic Article The case for selection at CCR5-Delta32.
Academic Article A draft sequence of the Neandertal genome.
Academic Article Dissecting direct reprogramming through integrative genomic analysis.
Academic Article Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.
Academic Article Identifying recent adaptations in large-scale genomic data.
Academic Article Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae.
Academic Article A genomewide linkage-disequilibrium scan localizes the Saguenay-Lac-Saint-Jean cytochrome oxidase deficiency to 2p16.
Academic Article Quality scores and SNP detection in sequencing-by-synthesis systems.
Academic Article Assessing mapping progress in the Human Genome Project.
Academic Article On the sequencing of the human genome.
Academic Article Initial genome sequencing and analysis of multiple myeloma.
Academic Article Interacting genetic loci cause airway hyperresponsiveness.
Academic Article Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Academic Article Evolution of genes and genomes on the Drosophila phylogeny.
Academic Article Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Academic Article A landscape of driver mutations in melanoma.
Academic Article Construction of a large-insert yeast artificial chromosome library of the mouse genome.
Academic Article Assisted assembly: how to improve a de novo genome assembly by using related species.
Academic Article Comparative epigenomic analysis of murine and human adipogenesis.
Academic Article Genome-sequencing anniversary. The accelerator.
Academic Article Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
Academic Article Building human genome maps with radiation hybrids.
Academic Article Genetic isolation of iddm 1 on chromosome 4 in the biobreeding (BB) rat.
Academic Article Identification of polymorphic simple sequence repeats in the genome of the zebrafish.
Academic Article Genomics: launching a revolution in medicine.
Academic Article A magnetic attraction to high-throughput genomics.
Academic Article Analysing complex genetic traits with chromosome substitution strains.
Academic Article Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse.
Academic Article Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study.
Academic Article Highly parallel identification of essential genes in cancer cells.
Academic Article An integrated genetic linkage map of the laboratory rat.
Academic Article Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma.
Academic Article Genome-scale DNA methylation maps of pluripotent and differentiated cells.
Academic Article Genetic mapping in human disease.
Academic Article Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis.
Academic Article Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.
Academic Article Initial impact of the sequencing of the human genome.
Academic Article Genome sequence, comparative analysis, and population genetics of the domestic horse.
Academic Article Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.
Academic Article Initial sequencing and comparative analysis of the mouse genome.
Academic Article Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.
Academic Article Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.
Academic Article Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.
Academic Article DNA sequence and analysis of human chromosome 18.
Academic Article Genome sequence, comparative analysis and haplotype structure of the domestic dog.
Academic Article Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.
Academic Article Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion.
Academic Article A radiation hybrid map of mouse genes.
Academic Article Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.
Academic Article The NIH Roadmap Epigenomics Mapping Consortium.
Academic Article The genomic complexity of primary human prostate cancer.
Academic Article The genome of the green anole lizard and a comparative analysis with birds and mammals.
Academic Article The genetic landscape of high-risk neuroblastoma.
Academic Article Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci.
Academic Article An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing.
Academic Article Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.
Academic Article Positive natural selection in the human lineage.
Academic Article Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Academic Article Software availability.
Academic Article Integrative analysis of the melanoma transcriptome.
Academic Article A genetic linkage map of the human genome.
Academic Article A nonparametric approach for mapping quantitative trait loci.
Academic Article Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping.
Academic Article Finding similarities and differences among genomes.
Academic Article High-quality draft assemblies of mammalian genomes from massively parallel sequence data.
Academic Article Genetic resistance to diet-induced obesity in chromosome substitution strains of mice.
Academic Article Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Academic Article Lessons from the cancer genome.
Academic Article Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.
Academic Article Genomic maps and comparative analysis of histone modifications in human and mouse.
Academic Article A high-resolution map of human evolutionary constraint using 29 mammals.
Academic Article Melanoma genome sequencing reveals frequent PREX2 mutations.
Academic Article A YAC-based physical map of the mouse genome.
Academic Article Human and mouse gene structure: comparative analysis and application to exon prediction.
Academic Article Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation.
Academic Article Linkage disequilibrium in the human genome.
Academic Article A large family of ancient repeat elements in the human genome is under strong selection.
Academic Article Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results.
Academic Article Mapping the mouse genome: current status and future prospects.
Academic Article Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Academic Article Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.
Academic Article Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples.
Academic Article Genomewide scan of multiple sclerosis in Finnish multiplex families.
Academic Article Dissecting the regulatory circuitry of a eukaryotic genome.
Academic Article Scientific commentary: the scientific foundations and medical and social prospects of the Human Genome Project.
Academic Article High-resolution haplotype structure in the human genome.
Academic Article Progress in sequencing the mouse genome.
Academic Article International network of cancer genome projects.
Concept Genome-Wide Association Study
Concept Genome, Archaeal
Concept Genome
Concept Genome, Protozoan
Concept Genome, Insect
Concept Genome, Human
Concept Human Genome Project
Concept Genome, Mitochondrial
Concept Genome, Fungal
Concept Genome, Viral
Concept Genome, Bacterial
Academic Article Punctuated evolution of prostate cancer genomes.
Academic Article Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Academic Article The African coelacanth genome provides insights into tetrapod evolution.
Academic Article Comprehensive molecular characterization of clear cell renal cell carcinoma.
Academic Article The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.
Academic Article Integrated genomic characterization of endometrial carcinoma.
Academic Article The Cancer Genome Atlas Pan-Cancer analysis project.
Academic Article High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.
Academic Article Genetic screens in human cells using the CRISPR-Cas9 system.
Academic Article Discovery and saturation analysis of cancer genes across 21 tumour types.
Academic Article Searching for missing heritability: designing rare variant association studies.
Academic Article A polygenic burden of rare disruptive mutations in schizophrenia.
Academic Article An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.
Academic Article Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Academic Article Development and applications of CRISPR-Cas9 for genome engineering.
Academic Article Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.
Academic Article Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.
Academic Article Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.
Academic Article The genomic substrate for adaptive radiation in African cichlid fish.
Academic Article Comprehensive variation discovery in single human genomes.
Academic Article Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Academic Article Measuring missing heritability: inferring the contribution of common variants.
Academic Article Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Academic Article A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.
Academic Article Cutting the Gordian helix--regulating genomic testing in the era of precision medicine.
Academic Article Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.
Academic Article Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.
Academic Article Brave New Genome.
Academic Article Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.
Academic Article Paired exome analysis of Barrett's esophagus and adenocarcinoma.
Academic Article Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.
Academic Article Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Academic Article Identification and characterization of essential genes in the human genome.
Academic Article Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.
Academic Article Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes.
Academic Article Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.
Academic Article The genetic architecture of type 2 diabetes.
Grant CENTER FOR GENOME RESEARCH
Grant CENTER FOR GENOME RESEARCH
Grant Large Scale Sequencing and Analysis of Genomes
Grant GENETIC AND PHYSICAL MAPPING RESOURCES
Grant GENOME RESEARCH
Grant SREA--GENOME RESEARCH REVIEW COMMITTEE
Grant SEQUENCING THE MOUSE GENOME
Grant LARGE SCALE IDENTIFICATION OF DNA VARIANTS
Academic Article Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels.
Academic Article A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.
Academic Article Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms.
Academic Article De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds.
Academic Article Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel.
Academic Article Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
Academic Article Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
Academic Article Cohesin Loss Eliminates All Loop Domains.
Academic Article A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients.
Academic Article Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
Academic Article Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.
Academic Article The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Academic Article Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Academic Article Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction.
Academic Article CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Academic Article Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines.
Academic Article Adopt a moratorium on heritable genome editing.
Academic Article 2018 William Allan Award: Discovering the Genes for Common Disease: From Families to Populations.
Academic Article Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
Academic Article Defining the core essential genome of Pseudomonas aeruginosa.
Academic Article The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research.
Academic Article Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
Academic Article A structural variation reference for medical and population genetics.
Academic Article Mapping and characterization of structural variation in 17,795 human genomes.
Academic Article Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.
Academic Article Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Academic Article Human Molecular Genetics and Genomics - Important Advances and Exciting Possibilities.
Academic Article Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Academic Article Genome-wide enhancer maps link risk variants to disease genes.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.