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One or more keywords matched the following items that are connected to Krivtsov, Andrei
Item TypeName
Academic Article H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Academic Article MLL translocations, histone modifications and leukaemia stem-cell development.
Academic Article HOXA9 is required for survival in human MLL-rearranged acute leukemias.
Academic Article MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Academic Article Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
Academic Article MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.
Concept Histone-Lysine N-Methyltransferase
Academic Article MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition.
Academic Article Loss of BAP1 function leads to EZH2-dependent transformation.
Academic Article Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia.
Academic Article A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
Academic Article Murine Retrovirally-Transduced Bone Marrow Engraftment Models of MLL-Fusion-Driven Acute Myelogenous Leukemias (AML).
Academic Article SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.
Academic Article The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
Academic Article Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia.
Academic Article Novel inhibitors of the histone methyltransferase DOT1L show potent antileukemic activity in patient-derived xenografts.
Search Criteria
  • Histone Lysine N Methyltransferase
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.