Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Brennan, Patrick
Item TypeName
Academic Article Mycobacterium tuberculosis cell envelope.
Academic Article Chemistry of the lyxose-containing mycobacteriophage receptors of Mycobacterium phlei/Mycobacterium smegmatis.
Academic Article Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol.
Academic Article The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.
Academic Article Phosphatidylinositol synthesis in mycobacteria.
Academic Article Characterization of mycobacterial protein glycosyltransferase activity using synthetic peptide acceptors in a cell-free assay.
Academic Article Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.
Academic Article Isothermal amplification and molecular typing of the obligate intracellular pathogen Mycobacterium leprae isolated from tissues of unknown origins.
Academic Article Characterization of the in vitro synthesized arabinan of mycobacterial cell walls.
Academic Article Structure, function and biogenesis of the mycobacterial cell wall.
Academic Article Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis.
Academic Article Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.
Academic Article Characterization of the specific antigenicity of Mycobacterium fortuitum.
Academic Article Synthetic mannosides act as acceptors for mycobacterial alpha1-6 mannosyltransferase.
Academic Article Mycobacterial arabinan biosynthesis: the use of synthetic arabinoside acceptors in the development of an arabinosyl transfer assay.
Academic Article Structural elucidation and antigenicity of a novel phenolic glycolipid antigen from Mycobacterium haemophilum.
Academic Article Mycolic acid biosynthesis: definition and targeting of the Claisen condensation step.
Academic Article Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis.
Academic Article New pyruvylated, glycosylated acyltrehaloses from Mycobacterium smegmatis strains, and their implications for phage resistance in mycobacteria.
Academic Article Cutaneous infections with rapidly growing mycobacteria.
Academic Article Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.
Academic Article The mycobacterial cell wall: biosynthesis of arabinogalactan and lipoarabinomannan.
Academic Article Synthesis of beta-D-arabinofuranosyl-1-monophosphoryl polyprenols: examination of their function as mycobacterial arabinosyl transferase donors.
Academic Article Biogenesis of the mycobacterial cell wall and the site of action of ethambutol.
Academic Article Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.
Academic Article Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis.
Academic Article Identification of the apparent carrier in mycolic acid synthesis.
Academic Article CD1-restricted T cell recognition of microbial lipoglycan antigens.
Academic Article Defective cell-mediated immunity in leprosy: failure of T cells from lepromatous leprosy patients to respond to Mycobacterium leprae is associated with defective expression of interleukin 2 receptors and is not reconstituted by interleukin 2.
Academic Article Biosynthesis of mycobacterial lipoarabinomannan.
Academic Article The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens.
Academic Article The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis.
Academic Article Activation of the pro-drug ethionamide is regulated in mycobacteria.
Academic Article Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase.
Academic Article Biosynthesis of the galactan component of the mycobacterial cell wall.
Academic Article Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
Academic Article Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis.
Academic Article Biosynthesis of the linkage region of the mycobacterial cell wall.
Academic Article A novel pathogenic taxon of the Mycobacterium tuberculosis complex, Canetti: characterization of an exceptional isolate from Africa.
Academic Article Synthesis and properties of methyl 5-(1'R,2'S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids.
Academic Article Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells.
Academic Article Trehalose-containing lipooligosaccharides of Mycobacterium gordonae: presence of a mono-O-methyltetra-O-acyltrehalose "core" and branching in the oligosaccharide backbone.
Academic Article Clinical trial of clarithromycin for cutaneous (disseminated) infection due to Mycobacterium chelonae.
Academic Article Structural definition of the glycopeptidolipids and the pyruvylated, glycosylated acyltrehalose from Mycobacterium butyricum.
Academic Article Characterization of the specific antigenicity of representatives of M. senegalense and related bacteria.
Academic Article Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.
Academic Article Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis.
Academic Article Ligation of arabinogalactan to peptidoglycan in the cell wall of Mycobacterium smegmatis requires concomitant synthesis of the two wall polymers.
Academic Article Further structural definition of a new family of glycopeptidolipids from Mycobacterium xenopi.
Academic Article Structural elucidation of a novel family of acyltrehaloses from Mycobacterium tuberculosis.
Academic Article A new interpretation of the structure of the mycolyl-arabinogalactan complex of Mycobacterium tuberculosis as revealed through characterization of oligoglycosylalditol fragments by fast-atom bombardment mass spectrometry and 1H nuclear magnetic resonance spectroscopy.
Concept Mycobacterium leprae
Concept Mycobacterium marinum
Concept Mycobacterium bovis
Concept Mycobacterium
Concept Mycobacterium chelonae
Concept Mycobacterium avium
Concept Mycobacterium smegmatis
Concept Mycobacterium tuberculosis
Academic Article Serum antibodies to mycobacterial antigens in active Crohn's disease.
Academic Article Population-based molecular epidemiology of leprosy in Cebu, Philippines.
Academic Article Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis.
Academic Article Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy.
Academic Article Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells.
Academic Article Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.
Academic Article The challenge of producing skin test antigens with minimal resources suitable for human application against a neglected tropical disease; leprosy.
Academic Article Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis.
Academic Article Towards an immunodiagnostic test for leprosy.
Academic Article Long-term survival and virulence of Mycobacterium leprae in amoebal cysts.
Academic Article Diagnosis of tuberculosis by a visually detectable immunoassay for lipoarabinomannan.
Academic Article Induction of inducible nitric oxide synthase-NO* by lipoarabinomannan of Mycobacterium tuberculosis is mediated by MEK1-ERK, MKK7-JNK, and NF-kappaB signaling pathways.
Grant MYCOBACTERIAL CELL WALL AND DRUG DISCOVERY
Grant Biogenesis of Lipoarabinomannan in Mycobacteria
Grant SPECIFIC ANTIGENS OF ATYPICAL MYCOBACTERIA
Grant M. tuberculosis Cell Wall Biogenesis;New Drugs;TB-HIV
Grant MYCOBACTERIUM LEPRAE GLYCOLIPID ANTIGENS
Grant Mode of Action of Thiorcarlide in Mycobacterium Tuberculosis
Grant MOLECULAR BIOLOGY AND TREATMENT OF M AVIUM
Grant CELL WALL OF M TUBERCULOSIS FOCUS FOR DRUG DISCOVERY
Grant DEFINED NATIVE ANTIGENS AND IMMUNITY TO TUBERCULOSIS
Grant ANTIGENS FROM PURIFIED MYCOBACTERIUM LEPRAE
Grant Leprosy Bacillus: From Genotype to Phenotype to Tools
Grant CELL WALL MUTANTS OF MYCOBACTERIUM TUBERCULOSIS
Academic Article Codominance of TLR2-dependent and TLR2-independent modulation of MHC class II in Mycobacterium tuberculosis infection in vivo.
Academic Article T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. Evidence for different kinetics and recognition of a wide spectrum of protein antigens.
Academic Article Mycobacterium smegmatis produces an HBHA homologue which is not involved in epithelial adherence.
Academic Article Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6.
Academic Article Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria.
Academic Article Recognition of a peptide antigen by heat shock--reactive gamma delta T lymphocytes.
Academic Article Capsular arabinomannans from Mycobacterium avium with morphotype-specific structural differences but identical biological activity.
Academic Article Evaluation of lipoarabinomannan for the serological diagnosis of tuberculosis.
Academic Article Conserved structure and function in the granulysin and NK-lysin peptide family.
Search Criteria
  • Mycobacterium
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.