Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Florez, Jose
Item TypeName
Academic Article Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.
Academic Article The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program.
Academic Article Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Academic Article Effects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Academic Article Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.
Academic Article The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.
Academic Article Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes Prevention Program.
Academic Article Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.
Academic Article Does metformin work for everyone? A genome-wide association study for metformin response.
Academic Article Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program.
Academic Article The C allele of ATM rs11212617 does not associate with metformin response in the Diabetes Prevention Program.
Academic Article Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone.
Concept Metformin
Academic Article Branched chain and aromatic amino acids change acutely following two medical therapies for type 2 diabetes mellitus.
Academic Article Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program.
Academic Article Genetic risk of progression to type 2 diabetes and response to intensive lifestyle or metformin in prediabetic women with and without a history of gestational diabetes mellitus.
Academic Article Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.
Academic Article Circulating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.
Academic Article An update on the pharmacogenomics of metformin: progress, problems and potential.
Academic Article Metformin pharmacogenomics: current status and future directions.
Academic Article It's not black and white: individualizing metformin treatment in type 2 diabetes.
Academic Article Factors affecting the decline in incidence of diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS).
Academic Article The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.
Academic Article Therapeutic Challenges in Diabetes Prevention: We Have Not Found the "Exercise Pill".
Academic Article Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants.
Academic Article Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program.
Academic Article Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.
Grant Genetic variation in drug targets for type 2 diabetes
Grant Discovery of Pharmacogenomic Biomarkers for Metformin Response
Grant Pharmacogenetics of the acute response to sulfonylurea and metformin treatment in
Grant Study to Understand the Genetics of the Acute Response to Metformin &Glipizide
Grant A Human-Centered Pharmacogenomic Screen of Metformin Action
Academic Article Pharmacogenetics in type 2 diabetes: precision medicine or discovery tool?
Academic Article Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.
Academic Article The pharmacogenetics of metformin.
Academic Article TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH).
Academic Article Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors.
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  • Metformin
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.