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One or more keywords matched the following properties of Hofer, Aldebaran
keywords Cyclic AMP Signaling
overview The Hofer laboratory applies a wide range of molecular, biophysical and fluorescence imaging techniques for probing interactions between two fundamental second messengers, cyclic AMP (cAMP) and calcium. Her team discovered a new signal transduction pathway that connects calcium levels within the ER lumen to the activation of the enzyme that generates cAMP, adenylyl cyclase. Her group has also devised approaches to monitor and tune cAMP in various subcellular compartments using targeted genetically encoded sensors and tools.
One or more keywords matched the following items that are connected to Hofer, Aldebaran
Item TypeName
Academic Article Store-operated cyclic AMP signalling mediated by STIM1.
Academic Article "cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate.
Academic Article The {omega}-3 fatty acid eicosapentaenoic acid elicits cAMP generation in colonic epithelial cells via a "store-operated" mechanism.
Academic Article Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia.
Academic Article Interactions between calcium and cAMP signaling.
Academic Article Real time measurements of water flow in amphibian gastric glands: modulation via the extracellular Ca2+-sensing receptor.
Academic Article Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations.
Academic Article Termination and activation of store-operated cyclic AMP production.
Academic Article Extracellular calcium and cAMP: second messengers as "third messengers"?
Concept Cyclic AMP-Dependent Protein Kinases
Concept Receptors, Cyclic AMP
Concept Cyclic AMP
Academic Article The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics.
Academic Article "Store-operated" cAMP signaling contributes to Ca2+-activated Cl- secretion in T84 colonic cells.
Grant Novel STIM1-dependent cyclic AMP signaling pathway in colonic epithelial function
Academic Article Interrogating cyclic AMP signaling using optical approaches.
Academic Article Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation.
Academic Article Cyclic AMP does double duty to support parallel signaling in primary cilium and cytosol.
Search Criteria
  • Cyclic AMP
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.