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One or more keywords matched the following items that are connected to Freeman, Gordon
Item TypeName
Academic Article TIM-1 induces T cell activation and inhibits the development of peripheral tolerance.
Academic Article Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.
Academic Article IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.
Academic Article Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model.
Academic Article Role of B7-1 in mediating an immune response to myeloid leukemia cells.
Academic Article B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct.
Concept Immunotherapy, Adoptive
Concept Immunotherapy
Academic Article PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.
Academic Article An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma.
Academic Article Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1).
Academic Article Therapeutic PD-1 pathway blockade augments with other modalities of immunotherapy T-cell function to prevent immune decline in ovarian cancer.
Academic Article Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Academic Article Immunotherapy advances for glioblastoma.
Academic Article PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma.
Academic Article A New B7:CD28 Family Checkpoint Target for Cancer Immunotherapy: HHLA2.
Academic Article The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy.
Academic Article The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma.
Academic Article Combination cancer immunotherapy and new immunomodulatory targets.
Academic Article Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy.
Academic Article Coinhibitory Pathways in Immunotherapy for Cancer.
Academic Article Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family.
Academic Article Learning from PD-1 Resistance: New Combination Strategies.
Grant Impact of Immunotherapy on Viral Immunity in Humans
Academic Article Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model.
Academic Article Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer.
Academic Article Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Academic Article Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Academic Article In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.
Academic Article Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.
Academic Article Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.
Academic Article T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity.
Academic Article TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.
Academic Article LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.
Academic Article Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response.
Academic Article Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV.
Academic Article Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-? and IL-12.
Academic Article PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
Academic Article Acidity changes immunology: a new VISTA pathway.
Academic Article The importance of exosomal PDL1 in tumour immune evasion.
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  • Immunotherapy
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.