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One or more keywords matched the following items that are connected to Freeman, Gordon
Item TypeName
Academic Article CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.
Academic Article The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response.
Academic Article Restoring function in exhausted CD8 T cells during chronic viral infection.
Academic Article Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity.
Academic Article CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions.
Academic Article An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells.
Academic Article Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation.
Academic Article The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase.
Academic Article Early signaling defects in human T cells anergized by T cell presentation of autoantigen.
Academic Article Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes.
Academic Article Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.
Academic Article Expression and regulation of CD5 on in vitro activated human B cells.
Academic Article The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1.
Academic Article Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).
Academic Article Regulation of human intestinal intraepithelial lymphocyte cytolytic function by biliary glycoprotein (CD66a).
Academic Article B7, a B-cell-restricted antigen that identifies preactivated B cells.
Academic Article Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity.
Academic Article Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production.
Academic Article Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool.
Academic Article Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.
Academic Article The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptor.
Academic Article Expression of MHC class II-associated invariant chain (Ii;CD74) in thymic epithelial neoplasms.
Academic Article Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.
Academic Article B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells.
Academic Article Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection.
Academic Article ICOS is critical for CD40-mediated antibody class switching.
Academic Article Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway.
Academic Article Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.
Academic Article CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion.
Academic Article Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.
Academic Article CD4+CD25high regulatory cells in human peripheral blood.
Academic Article Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation.
Academic Article Role of PD-1 in regulating acute infections.
Academic Article CD2 is involved in maintenance and reversal of human alloantigen-specific clonal anergy.
Academic Article Studies of in vitro activated CD5+ B cells.
Academic Article Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade.
Academic Article B7.2 expressed by T cells does not induce CD28-mediated costimulatory activity but retains CTLA4 binding: implications for induction of antitumor immunity to T cell tumors.
Academic Article The B7 family revisited.
Academic Article The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system.
Academic Article The B7-CD28 superfamily.
Academic Article CD40 ligand triggered interleukin-6 secretion in multiple myeloma.
Academic Article PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver.
Academic Article Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection.
Academic Article B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.
Academic Article Follicular dendritic cells contain a unique gene repertoire demonstrated by single-cell polymerase chain reaction.
Academic Article Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice.
Academic Article Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity.
Academic Article Blockade of the CD28 co-stimulatory pathway: a means to induce tolerance.
Academic Article Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice.
Academic Article CTLA4 mediates antigen-specific apoptosis of human T cells.
Academic Article ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.
Academic Article Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity.
Academic Article Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.
Academic Article Isolated human follicular dendritic cells display a unique antigenic phenotype.
Academic Article Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.
Academic Article B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation.
Academic Article The leukocyte semaphorin CD100 is expressed in most T-cell, but few B-cell, non-Hodgkin's lymphomas.
Academic Article B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.
Academic Article Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice.
Concept Antigens, Differentiation, B-Lymphocyte
Concept Antigens, Differentiation, T-Lymphocyte
Concept Antigens, Differentiation
Academic Article TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells.
Search Criteria
  • Antigens Differentiation
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.