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One or more keywords matched the following items that are connected to Bernhardt, Thomas
Item TypeName
Academic Article Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases.
Concept Penicillin-Binding Proteins
Academic Article Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms.
Academic Article Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.
Academic Article Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria.
Academic Article Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity.
Academic Article Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis in Streptococcus pneumoniae D39.
Grant Peptidoglycan Biogenesis in Escherichia Coli
Academic Article SEDS proteins are a widespread family of bacterial cell wall polymerases.
Academic Article The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli.
Academic Article Phosphorylation-dependent activation of the cell wall synthase PBP2a in Streptococcus pneumoniae by MacP.
Academic Article Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator in Pseudomonas aeruginosa.
Academic Article A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery.
Academic Article Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery.
Academic Article Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape.
Academic Article FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein.
Search Criteria
  • Penicillin V
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.