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One or more keywords matched the following items that are connected to Serhan, Charles
Item TypeName
Academic Article Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release.
Academic Article Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.
Academic Article Novel eicosanoid and docosanoid mediators: resolvins, docosatrienes, and neuroprotectins.
Academic Article Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers.
Academic Article Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX.
Academic Article Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
Academic Article Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes.
Academic Article Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals.
Academic Article Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.
Academic Article The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Academic Article Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease.
Academic Article Inosine monophosphate and aspirin-triggered 15-epi-lipoxin A4 act in concert to regulate neutrophil trafficking: additive actions of two new endogenous anti-inflammatory mediators.
Academic Article Aspirin-triggered 15-epi-lipoxin A4 biosynthesis in rat liver cells.
Academic Article Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell-cell interactions or a therapeutic opportunity?
Academic Article Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo.
Academic Article Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking.
Academic Article Local and systemic delivery of an aspirin-triggered lipoxin stable analog inhibits neutrophil trafficking.
Academic Article Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases.
Academic Article Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.
Academic Article Inhibition of allergen-induced eosinophil migration by lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4.
Academic Article Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 modulate adhesion molecule expression on human leukocytes in whole blood and inhibit neutrophil-endothelial cell adhesion.
Academic Article Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins.
Academic Article Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing.
Academic Article Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation.
Academic Article LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation.
Academic Article Transcellular regulation of eicosanoid biosynthesis.
Academic Article Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution.
Academic Article Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
Academic Article Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators.
Academic Article Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-alpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis relevant to periodontal diseases.
Academic Article Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins.
Academic Article Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial.
Academic Article Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils.
Academic Article Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression.
Academic Article Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis.
Academic Article Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation.
Academic Article Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.
Academic Article Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Academic Article Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
Academic Article Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit human neutrophil migration: comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells.
Academic Article Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis.
Academic Article Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis.
Academic Article Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.
Academic Article Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.
Academic Article Lipoxins and new lipid mediators in the resolution of inflammation.
Academic Article Angioplasty triggers intracoronary leukotrienes and lipoxin A4. Impact of aspirin therapy.
Academic Article 15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury.
Academic Article Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways.
Academic Article Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases.
Academic Article Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.
Academic Article A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution.
Academic Article Novel proresolving aspirin-triggered DHA pathway.
Academic Article Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation.
Academic Article Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.
Academic Article Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA.
Academic Article Aspirin triggered-lipoxin A4 reduces the adhesion of human polymorphonuclear neutrophils to endothelial cells initiated by preeclamptic plasma.
Academic Article Aspirin-triggered lipoxins (15-epi-LX) are generated by the human lung adenocarcinoma cell line (A549)-neutrophil interactions and are potent inhibitors of cell proliferation.
Academic Article Aspirin triggered lipid mediators: novel inhibitors of leucocyte trafficking.
Academic Article A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils.
Academic Article Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.
Academic Article Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent.
Academic Article Novel chemical mediators in the resolution of inflammation: resolvins and protectins.
Academic Article Exploring new approaches to the treatment of asthma: potential roles for lipoxins and aspirin-triggered lipid mediators.
Academic Article Novel pathways and endogenous mediators in anti-inflammation and resolution.
Academic Article Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis.
Academic Article Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4.
Academic Article Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
Academic Article New endogenous anti-inflammatory and proresolving lipid mediators: implications for rheumatic diseases.
Academic Article Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side.
Academic Article Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents.
Academic Article Polyisoprenyl phosphates: natural antiinflammatory lipid signals.
Academic Article Lipoxins and aspirin-triggered lipoxins in airway responses.
Academic Article Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins.
Academic Article Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial.
Academic Article Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins.
Academic Article Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.
Academic Article Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4).
Academic Article Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution.
Academic Article Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug.
Academic Article The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids.
Academic Article Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation.
Academic Article Stereocontrolled total synthesis of the potent anti-inflammatory and pro-resolving lipid mediator resolvin D3 and its aspirin-triggered 17R-epimer.
Academic Article Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke.
Academic Article Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6.
Academic Article Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators.
Academic Article Cell-cell interaction in the transcellular biosynthesis of novel omega-3-derived lipid mediators.
Academic Article New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications.
Academic Article Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.
Academic Article Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
Academic Article Aspirin-triggered 15-epi-lipoxin A4 and stable analogs on lipoxin A4 are potent inhibitors of acute inflammation. Receptors and pathways.
Academic Article Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells.
Academic Article Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing.
Academic Article Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus.
Concept Aspirin
Academic Article Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion.
Academic Article Stereocontrolled total synthesis of neuroprotectin D1 / protectin D1 and its aspirin-triggered stereoisomer.
Academic Article Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue.
Academic Article Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome.
Academic Article Protective actions of aspirin-triggered (17R) resolvin D1 and its analogue, 17R-hydroxy-19-para-fluorophenoxy-resolvin D1 methyl ester, in C5a-dependent IgG immune complex-induced inflammation and lung injury.
Academic Article Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines.
Academic Article The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution.
Academic Article Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling.
Academic Article Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia.
Academic Article Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation.
Grant Mechanism of action of omega-3 fatty acids in brain injury
Grant Controlling cancer with aspirin-triggered stimulation of resolution
Grant BLOOD CELL LIPOXYGENASE PRODUCTS--FORMATION AND ACTION
Academic Article Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas.
Academic Article Addition of aspirin to a fish oil-rich diet decreases inflammation and atherosclerosis in ApoE-null mice.
Academic Article Aspirin-triggered proresolving mediators stimulate resolution in cancer.
Search Criteria
  • Aspirin
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.