Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Lopez, Mary
Item TypeName
Academic Article A luminescent europium complex for the sensitive detection of proteins and nucleic acids immobilized on membrane supports.
Academic Article Tris-tricine and Tris-borate buffer systems provide better estimates of human mesothelial cell intermediate filament protein molecular weights than the standard Tris-glycine system.
Academic Article Background-free, high sensitivity staining of proteins in one- and two-dimensional sodium dodecyl sulfate-polyacrylamide gels using a luminescent ruthenium complex.
Academic Article Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis.
Academic Article Proteomic patterns for classification of ovarian cancer and CTCL serum samples utilizing peak pairs indicative of post-translational modifications.
Academic Article Better approaches to finding the needle in a haystack: optimizing proteome analysis through automation.
Academic Article An improved formulation of SYPRO Ruby protein gel stain: comparison with the original formulation and with a ruthenium II tris (bathophenanthroline disulfonate) formulation.
Academic Article Development of a dedicated two-dimensional gel electrophoresis system that provides optimal pattern reproducibility and polypeptide resolution.
Academic Article Reproducibility of polypeptide spot positions in two-dimensional gels run using carrier ampholytes in the isoelectric focusing dimension.
Academic Article Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples.
Academic Article Regulation of hepatic glycogen in the insulin-like growth factor II-deficient mouse.
Academic Article 2-D electrophoresis using carrier ampholytes in the first dimension (IEF).
Academic Article Applied proteomics: mitochondrial proteins and effect on function.
Academic Article Protein micro- and macroarrays: digitizing the proteome.
Academic Article Expression of growth hormone-binding protein with a hydrophilic carboxyl terminus by the mouse placenta: studies in vivo and in vitro.
Academic Article Effect of kainic acid treatment on insulin-like growth factor-2 receptors in the IGF2-deficient adult mouse brain.
Academic Article Heart-brain signaling in patent foramen ovale-related stroke: differential plasma proteomic expression patterns revealed with a 2-pass liquid chromatography-tandem mass spectrometry discovery workflow.
Academic Article A mechanically strong matrix for protein electrophoresis with enhanced silver staining properties.
Academic Article Ultrasensitive fluorescence protein detection in isoelectric focusing gels using a ruthenium metal chelate stain.
Academic Article Performance validation of an improved Xenon-arc lamp-based CCD camera system for multispectral imaging in proteomics.
Academic Article A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta-class of GSTs.
Academic Article SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness.
Academic Article Interlaboratory reproducibility of selective reaction monitoring assays using multiple upfront analyte enrichment strategies.
Academic Article Biomarker discovery and analysis platform: application to Alzheimer's disease.
Academic Article Effect of various detergents on protein migration in the second dimension of two-dimensional gels.
Academic Article Discrimination of ischemic and hemorrhagic strokes using a multiplexed, mass spectrometry-based assay for serum apolipoproteins coupled to multi-marker ROC algorithm.
Academic Article Placental glycogen stores are increased in mice with H19 null mutations but not in those with insulin or IGF type 1 receptor mutations.
Academic Article Evaluation of absolute peptide quantitation strategies using selected reaction monitoring.
Academic Article A novel, high-throughput workflow for discovery and identification of serum carrier protein-bound peptide biomarker candidates in ovarian cancer samples.
Academic Article Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells.
Academic Article High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation.
Academic Article A luminescent ruthenium complex for ultrasensitive detection of proteins immobilized on membrane supports.
Academic Article Comparison of three different fluorescent visualization strategies for detecting Escherichia coli ATP synthase subunits after sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Academic Article Protein quantification by mass spectrometry: is it ready for prime time?
Academic Article A robust biomarker discovery pipeline for high-performance mass spectrometry data.
Academic Article Mass spectrometric discovery and selective reaction monitoring (SRM) of putative protein biomarker candidates in first trimester Trisomy 21 maternal serum.
Academic Article Proteomic analysis of mitochondrial proteins.
Academic Article Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells.
Academic Article Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel PerfectPair mass difference algorithm.
Academic Article Multiwell in-gel protein digestion and microscale sample preparation for protein identification by mass spectrometry.
Academic Article IGF2 knockout mice are resistant to kainic acid-induced seizures and neurodegeneration.
Academic Article Pituitary-placental interaction: hypophysectomy modulates the secretion of mouse placental lactogen-I.
Academic Article High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures.
Academic Article Igf2 deficiency results in delayed lung development at the end of gestation.
Academic Article Decreased motoneuron survival in Igf2 null mice after sciatic nerve transection.
Academic Article Insulin-like growth factor II affects the appearance and glycogen content of glycogen cells in the murine placenta.
Academic Article A comparison of silver stain and SYPRO Ruby Protein Gel Stain with respect to protein detection in two-dimensional gels and identification by peptide mass profiling.
Academic Article High-content proteomics: fluorescence multiplexing using an integrated, high-sensitivity, multiwavelength charge-coupled device imaging system.
Concept Immunohistochemistry
Concept Structure-Activity Relationship
Concept Pituitary Gland
Concept Young Adult
Concept Cohort Studies
Concept Mice
Concept Substrate Specificity
Concept Proteomics
Concept Biochemistry
Concept Chemokines
Concept Oligonucleotide Array Sequence Analysis
Concept Acute-Phase Proteins
Concept Electrophoresis, Gel, Two-Dimensional
Concept Brassica
Concept Luminescent Measurements
Concept Prostate-Specific Antigen
Concept HEK293 Cells
Concept Chromatography, Liquid
Concept Obesity
Concept Immunoprecipitation
Concept Chromatin
Concept Cerebrovascular Disorders
Concept Insulin-Like Growth Factor II
Concept Alzheimer Disease
Concept Blood Chemical Analysis
Concept Bacterial Proton-Translocating ATPases
Concept Binding Sites
Concept Apolipoproteins
Concept Rats, Inbred Lew
Concept Erythropoiesis
Concept Acrylic Resins
Concept Down Syndrome
Concept Antibodies, Monoclonal
Concept CA-125 Antigen
Concept Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Concept Immunoglobulin Fragments
Concept Rosaniline Dyes
Concept Antioxidants
Concept Oxidation-Reduction
Concept Stroke
Concept Mice, Inbred C3H
Concept Hydrogen Peroxide
Concept STAT3 Transcription Factor
Concept Blotting, Western
Concept Case-Control Studies
Concept Phagosomes
Concept Receptor, IGF Type 2
Concept Erythrocytes
Concept Binding, Competitive
Concept Blotting, Northern
Concept Chlorides
Concept Mammals
Concept Aged
Concept Adenosine Triphosphate
Concept Amino Acid Sequence
Concept Insulin-Like Growth Factor I
Concept Chemical Fractionation
Concept Protoporphyrins
Concept Mice, Knockout
Concept Mice, Inbred Strains
Concept Chromatography, Reverse-Phase
Concept Spectrometry, Fluorescence
Concept Glycine
Concept Antibody Specificity
Concept Rats
Concept Sequence Homology, Amino Acid
Concept Autoradiography
Concept Peptide Mapping
Concept Serum
Concept Osteoarthritis, Knee
Concept Ion Transport
Concept Brain Damage, Chronic
Concept Peptide Library
Concept Body Mass Index
Concept Tandem Mass Spectrometry
Concept Diagnosis, Differential
Concept Protein Binding
Concept DNA Methylation
Concept Apoptosis
Concept Fetal Development
Concept Data Interpretation, Statistical
Concept Mass Spectrometry
Concept Potassium Channels, Tandem Pore Domain
Concept Protein Processing, Post-Translational
Concept Cell Count
Concept Cartilage
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Antibiotics, Antineoplastic
Concept Carbohydrate Metabolism
Concept RNA-Binding Proteins
Concept Protein Array Analysis
Concept Isoelectric Focusing
Concept Superoxides
Concept Blood Protein Electrophoresis
Concept MicroRNAs
Concept Chromatin Assembly and Disassembly
Concept Tryptophan
Concept Biotechnology
Concept Complement System Proteins
Concept Mice, Inbred C57BL
Concept Computational Biology
Concept Mitochondria, Liver
Concept Middle Aged
Concept Arabidopsis Proteins
Concept Limbic System
Concept Hippocampus
Concept Blood Coagulation Factors
Concept Aging
Concept Gels
Concept Databases, Protein
Concept Cysteine
Concept Epilepsy
Concept Humans
Concept Bleomycin
Concept Cerebellum
Concept Down-Regulation
Concept Jurkat Cells
Concept Cattle
Concept Organ Size
Concept Escherichia coli
Concept Glucose Transport Proteins, Facilitative
Concept Electrophoresis, Polyacrylamide Gel
Concept Electrophoresis
Concept Ultraviolet Rays
Concept Mitochondria
Concept Brain
Concept Microscopy, Video
Concept Aged, 80 and over
Concept Foramen Ovale, Patent
Concept Mice, Transgenic
Concept Phosphorylation
Concept Immunoglobulin G
Concept Boric Acids
Concept Mitochondria, Heart
Concept Signal Transduction
Concept Apolipoproteins E
Concept Body Size
Concept Adipose Tissue
Concept Fetal Blood
Concept Glycosylation
Concept Fetal Organ Maturity
Concept Mice, Inbred BALB C
Concept Catalysis
Concept Disulfides
Concept Organogenesis
Concept Receptor, IGF Type 1
Academic Article Targeted selected reaction monitoring mass spectrometric immunoassay for insulin-like growth factor 1.
Academic Article Parallel workflow for high-throughput (>1,000 samples/day) quantitative analysis of human insulin-like growth factor 1 using mass spectrometric immunoassay.
Academic Article The role of apolipoprotein E in neurodegeneration and cardiovascular disease.
Academic Article An automated, high-throughput method for targeted quantification of intact insulin and its therapeutic analogs in human serum or plasma coupling mass spectrometric immunoassay with high resolution and accurate mass detection (MSIA-HR/AM).
Academic Article Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.
Academic Article LC-MS candidate reference methods for the harmonisation of parathyroid hormone (PTH) measurement: a review of recent developments and future considerations.
Academic Article Hybrid data acquisition and processing strategies with increased throughput and selectivity: pSMART analysis for global qualitative and quantitative analysis.
Academic Article Delineating monoclonal antibody specificity by mass spectrometry.
Academic Article Proteomic signatures of serum albumin-bound proteins from stroke patients with and without endovascular closure of PFO are significantly different and suggest a novel mechanism for cholesterol efflux.
Academic Article Mass spectrometry assays of plasma biomarkers to predict radiographic progression of knee osteoarthritis.
Academic Article A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA-SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts.
Academic Article Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Grant Fetal-Glycogen Regulation by Insulin-like Growth Factors
Grant IGFII AND PERINATAL CARBOHYDRATE METABOLISM
Grant IGF II AND PLACENTAL AND FETAL DEVELOPMENT
Academic Article Disruption of the Igf2 gene alters hepatic lipid homeostasis and gene expression in the newborn mouse.
Search Criteria
  • IGF
  • 1
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.