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One or more keywords matched the following items that are connected to Austen, K
Item TypeName
Academic Article Leukotriene C4 synthase.
Academic Article Molecular cloning of the gene for mouse leukotriene-C4 synthase.
Academic Article Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics.
Academic Article The biochemical, molecular, and genomic aspects of leukotriene C4 synthase.
Academic Article Purification of human leukotriene C4 synthase.
Academic Article Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing.
Academic Article Doing what I like.
Academic Article Secretory granule mediator release and generation of oxidative metabolites of arachidonic acid via Fc-IgG receptor bridging in mouse mast cells.
Academic Article Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice.
Academic Article Attenuated zymosan-induced peritoneal vascular permeability and IgE-dependent passive cutaneous anaphylaxis in mice lacking leukotriene C4 synthase.
Academic Article Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.
Academic Article Acute and chronic suppression of leukotriene B4 synthesis ex vivo in neutrophils from patients with rheumatoid arthritis beginning treatment with methotrexate.
Academic Article Cell-specific transcription of leukotriene C(4) synthase involves a Kruppel-like transcription factor and Sp1.
Academic Article Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells.
Academic Article Characterization of the gene for leukotriene C4 synthase and its chromosomal localization.
Academic Article T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.
Academic Article Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis.
Academic Article Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells.
Academic Article Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R.
Academic Article Generation of leukotriene C4, leukotriene B4, and prostaglandin D2 by immunologically activated rat intestinal mucosa mast cells.
Academic Article GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.
Academic Article Localization of the site of the bronchoconstrictor effects of leukotriene C4 compared with that of histamine in asthmatic subjects.
Academic Article Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis.
Academic Article The diverse roles of mast cells.
Academic Article Eosinophil phenotypes and LTC4 generation in vitro and in hypereosinophilic states.
Academic Article The catalytic architecture of leukotriene C4 synthase with two arginine residues.
Academic Article Molecular cloning, expression and characterization of mouse leukotriene C4 synthase.
Academic Article Additional functions for the cysteinyl leukotrienes recognized through studies of inflammatory processes in null strains.
Academic Article The mast cell and the cysteinyl leukotrienes.
Academic Article Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation.
Academic Article Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists.
Academic Article Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors.
Academic Article Bronchoconstrictor effects of leukotriene C in humans.
Academic Article Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation.
Academic Article The identification and formation of 20-aldehyde leukotriene B4.
Academic Article The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils.
Academic Article The cell biology and biochemistry of leukotriene C4 biosynthesis.
Academic Article Site-directed mutagenesis of human leukotriene C4 synthase.
Academic Article Human leukotriene C(4) synthase at 4.5 A resolution in projection.
Academic Article Leukotriene C4 uses a probenecid-sensitive export carrier that does not recognize leukotriene B4.
Academic Article The immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase.
Academic Article Purification of human lung leukotriene C4 synthase and preparation of a polyclonal antibody.
Academic Article Mouse bone marrow-derived mast cells cocultured with fibroblasts. Morphology and stimulation-induced release of histamine, leukotriene B4, leukotriene C4, and prostaglandin D2.
Academic Article Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.
Academic Article Leukotriene receptors and aspirin sensitivity.
Academic Article Identification of an aldehyde dehydrogenase in the microsomes of human polymorphonuclear leukocytes that metabolizes 20-aldehyde leukotriene B4.
Academic Article Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils.
Academic Article Neutrophil-derived leukotriene B4 is required for inflammatory arthritis.
Academic Article GPR17 regulates immune pulmonary inflammation induced by house dust mites.
Academic Article Perturbation of beta-glucan receptors on human neutrophils initiates phagocytosis and leukotriene B4 production.
Academic Article Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.
Academic Article The mechanism of leukotriene B4 export from human polymorphonuclear leukocytes.
Academic Article The Paul Kallós Memorial Lecture. From slow-reacting substance of anaphylaxis to leukotriene C4 synthase.
Academic Article Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases.
Academic Article Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.
Academic Article Leukotriene B4 action on endothelium mediates augmented neutrophil/endothelial adhesion.
Academic Article Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteers.
Academic Article Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes.
Academic Article Leukotrienes and airway responses.
Academic Article Expression cloning of human LTC4 synthase.
Academic Article The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications.
Academic Article Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cells.
Academic Article Eosinophils altered phenotypically and primed by culture with granulocyte/macrophage colony-stimulating factor and 3T3 fibroblasts generate leukotriene C4 in response to FMLP.
Academic Article Leukocyte immunoglobulin-like receptors: novel innate receptors for human basophil activation and inhibition.
Academic Article Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35.
Academic Article Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate.
Academic Article The cysteinyl leukotrienes: where do they come from? What are they? Where are they going?
Academic Article Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors.
Academic Article Leukotriene C4 synthase: a pivotal enzyme in cellular biosynthesis of the cysteinyl leukotrienes.
Academic Article Leukotriene C4 binding proteins and their implications.
Academic Article Properties of highly purified leukotriene C4 synthase of guinea pig lung.
Concept Leukotriene A4
Concept Leukotriene C4
Concept Leukotriene E4
Concept Leukotriene B4
Concept Leukotriene Antagonists
Concept Leukotriene D4
Concept Receptors, Leukotriene B4
Concept Leukotrienes
Concept Receptors, Leukotriene
Academic Article Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand.
Academic Article Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization.
Academic Article Mast-cell secretion and structure-functional relationships of granule constituents and leukotrienes.
Academic Article Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99.
Academic Article CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma.
Academic Article Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.
Academic Article Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.
Academic Article Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions.
Search Criteria
  • Leukotriene C4
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.