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Zinc(II)-mediated enhancement of the agonist activity of histidine-substituted parathyroid hormone(1-14) analogues.
Residue 19 of the parathyroid hormone: structural consequences.
Amino-terminal parathyroid hormone fragment analogs containing alpha,alpha-di-alkyl amino acids at positions 1 and 3.
Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor.
Backbone-methylated analogues of the principle receptor binding region of human parathyroid hormone. Evidence for binding to both the N-terminal extracellular domain and extracellular loop region.
Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor.
Cooperative interaction of arginine-19 and the N-terminal signaling domain in the affinity and potency of parathyroid hormone.
C-terminal analogues of parathyroid hormone: effect of C-terminus function on helical structure, stability, and bioactivity.
Analysis of parathyroid hormone's principal receptor-binding region by site-directed mutagenesis and analog design.