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One or more keywords matched the following items that are connected to Hahn, William
Item TypeName
Academic Article Lentivirus-delivered stable gene silencing by RNAi in primary cells.
Academic Article Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy.
Academic Article Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene.
Academic Article Liprin alpha1 interacts with PP2A B56gamma.
Academic Article CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Academic Article Minimizing the risk of reporting false positives in large-scale RNAi screens.
Academic Article An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.
Academic Article CK1epsilon is required for breast cancers dependent on beta-catenin activity.
Academic Article Therapeutic implications of GIPC1 silencing in cancer.
Academic Article Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Academic Article ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens.
Academic Article SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
Academic Article Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells.
Academic Article Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
Academic Article Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Academic Article The intersection of genetic and chemical genomic screens identifies GSK-3a as a target in human acute myeloid leukemia.
Academic Article Proteomic and genetic approaches identify Syk as an AML target.
Academic Article Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.
Concept RNA Interference
Academic Article Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.
Academic Article PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.
Academic Article DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Academic Article The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.
Academic Article Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy.
Academic Article Integrated genetic and pharmacologic interrogation of rare cancers.
Grant Integrated genomic approaches to identify and validate cancer targets
Academic Article Defining a Cancer Dependency Map.
Academic Article Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens.
Academic Article Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.
Academic Article Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition.
Academic Article Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers.
Academic Article Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer.
Search Criteria
  • RNA Interference
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.