Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Hafler, David
Item TypeName
Academic Article IL-12 induces human T cells secreting IL-10 with IFN-gamma.
Academic Article CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.
Academic Article HTLV-I-induced T-cell activation.
Academic Article Activation of human T cell lymphotropic virus type I-infected T cells is independent of B7 costimulation.
Academic Article Downregulation of IL-10 secretion and enhanced antigen-presenting abilities following HTLV-I infection of T cells.
Academic Article Decreases in interleukin-4 secretion by invariant CD4(-)CD8(-)V alpha 24J alpha Q T cells in peripheral blood of patientswith relapsing-remitting multiple sclerosis.
Academic Article Suppressor T cells in human diseases.
Academic Article Differential responses of invariant V alpha 24J alpha Q T cells and MHC class II-restricted CD4+ T cells to dexamethasone.
Academic Article Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis.
Academic Article Myelin basic protein reactive Th2 T cells are found in acute disseminated encephalomyelitis.
Academic Article Induction of anergy in CD8 T cells by B cell presentation of antigen.
Academic Article Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: increased interleukin-4 production and associated eosinophilia.
Academic Article Direct analysis of viral-specific CD8+ T cells with soluble HLA-A2/Tax11-19 tetramer complexes in patients with human T cell lymphotropic virus-associated myelopathy.
Academic Article Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.
Academic Article Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells.
Academic Article T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions.
Academic Article Frequency analysis of CD4+CD8+ T cells cloned with IL-4.
Academic Article Autoantigen recognition by human CD8 T cell clones: enhanced agonist response induced by altered peptide ligands.
Academic Article Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation.
Academic Article Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease.
Academic Article Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis.
Academic Article Inhibition of human CD4(+)CD25(+high) regulatory T cell function.
Academic Article Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes.
Academic Article Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies.
Academic Article Regulation of T cell clone function via CD4 and CD8 molecules. Anti-CD4 can mediate two distinct inhibitory activities.
Academic Article Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection.
Academic Article CD4+CD25+ regulatory cells from human peripheral blood express very high levels of CD25 ex vivo.
Academic Article Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.
Academic Article Increased protein kinase C activity in human memory T cells.
Academic Article Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis.
Academic Article Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis.
Academic Article Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99.
Academic Article Risk alleles for multiple sclerosis identified by a genomewide study.
Academic Article Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes.
Academic Article Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.
Academic Article Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide.
Academic Article Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis.
Academic Article Pulse cyclophosphamide plus methylprednisolone induces myelin-antigen-specific IL-4-secreting T cells in multiple sclerosis patients.
Academic Article Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand.
Academic Article Heterophile antibodies indicate progression of autoimmunity in human type 1 diabetes mellitus before clinical onset.
Academic Article IL-21 and TGF-beta are required for differentiation of human T(H)17 cells.
Academic Article Engineered interleukin-2 antagonists for the inhibition of regulatory T cells.
Academic Article Restricted T cell expression of IL-2/IFN-gamma mRNA in human inflammatory disease.
Academic Article A novel population of B7-1+ T cells producing intracellular IL-4 is decreased in patients with multiple sclerosis.
Academic Article CD4+CD25high regulatory cells in human peripheral blood.
Academic Article Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility.
Academic Article IL-17-producing human peripheral regulatory T cells retain suppressive function.
Academic Article Lymphokine regulation of CD45R expression on human T cell clones.
Academic Article On-chip activation and subsequent detection of individual antigen-specific T cells.
Academic Article Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis.
Academic Article CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis.
Academic Article Abnormal Tr1 differentiation in multiple sclerosis.
Academic Article The purification and functional analysis of human CD4+CD25high regulatory T cells.
Academic Article Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients.
Academic Article GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.
Academic Article Interleukin-1 corrects the defective autologous mixed lymphocyte response in multiple sclerosis.
Academic Article In vitro evidence that subcutaneous administration of glatiramer acetate induces hyporesponsive T cells in patients with multiple sclerosis.
Academic Article Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.
Academic Article Human regulatory T cells and their role in autoimmune disease.
Academic Article Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis.
Academic Article Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis.
Academic Article T-T cell interactions are mediated by adhesion molecules.
Academic Article Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis.
Academic Article A review of T-cell receptors in multiple sclerosis: clonal expansion and persistence of human T-cells specific for an immunodominant myelin basic protein peptide.
Academic Article RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels.
Academic Article A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis.
Academic Article Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells.
Academic Article Inflammatory cerebrospinal fluid T cells have activation requirements characteristic of CD4+CD45RA- T cells.
Academic Article Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.
Academic Article Induction and molecular signature of pathogenic TH17 cells.
Academic Article Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+CD25+ T cells.
Academic Article FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation.
Academic Article Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions.
Academic Article Investigation of in vivo activated T cells in multiple sclerosis and inflammatory central nervous system diseases.
Academic Article Immunology. An innate role for IL-17.
Academic Article TGF-beta induces IL-9 production from human Th17 cells.
Academic Article Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells.
Academic Article MHC class II expression identifies functionally distinct human regulatory T cells.
Academic Article IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
Academic Article Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.
Academic Article Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response.
Academic Article The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases.
Concept Interleukin-5
Concept Interleukin-2 Receptor alpha Subunit
Concept Interleukin-12
Concept Receptors, Interleukin-2
Concept Interleukin-17
Concept Interleukin-1beta
Concept Interleukin-4
Concept Interleukin-23
Concept Interleukin-6
Concept Interleukin 1 Receptor Antagonist Protein
Concept Interleukin-10
Concept Receptors, Interleukin-1
Concept Interleukin-7
Concept Interleukins
Concept Receptors, Interleukin-17
Concept Interleukin-7 Receptor alpha Subunit
Concept Interleukin-1
Concept Interleukin-9
Concept Interleukin-2
Concept Interleukin-13
Academic Article Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Academic Article TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells.
Academic Article Enhanced suppressor function of TIM-3+ FoxP3+ regulatory T cells.
Academic Article Systems immunology reveals markers of susceptibility to West Nile virus infection.
Academic Article Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults.
Academic Article TGF-ß1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.
Academic Article Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme.
Academic Article Podoplanin is a negative regulator of Th17 inflammation.
Academic Article Activated ß-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity.
Search Criteria
  • Interleukins
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.