Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Hafler, David
Item TypeName
Academic Article HTLV-I-induced T-cell activation.
Academic Article Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers.
Academic Article Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells.
Academic Article T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions.
Academic Article Examination of CD8+ T cell function in humans using MHC class I tetramers: similar cytotoxicity but variable proliferation and cytokine production among different clonal CD8+ T cells specific to a single viral epitope.
Academic Article Immune tolerance and the nervous system.
Academic Article Variable immortalizing potential and frequent virus latency in blood-derived T-cell clones infected with human T-cell leukemia virus type I.
Academic Article Early signaling defects in human T cells anergized by T cell presentation of autoantigen.
Academic Article Inhibition of human CD4(+)CD25(+high) regulatory T cell function.
Academic Article Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes.
Academic Article Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies.
Academic Article Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving.
Academic Article CD4+CD25+ regulatory cells from human peripheral blood express very high levels of CD25 ex vivo.
Academic Article T helper cell differentiation in multiple sclerosis and autoimmunity.
Academic Article Oral administration of myelin induces antigen-specific TGF-beta 1-secreting T cells in multiple sclerosis patients.
Academic Article Polyfunctional responses by human T cells result from sequential release of cytokines.
Academic Article Multiple sclerosis.
Academic Article Seminars in medicine of the Beth Israel Hospital, Boston. Pathogenesis of diseases induced by human lymphotropic virus type I infection.
Academic Article Interleukin-1 corrects the defective autologous mixed lymphocyte response in multiple sclerosis.
Academic Article In vitro evidence that subcutaneous administration of glatiramer acetate induces hyporesponsive T cells in patients with multiple sclerosis.
Academic Article Cytokine secretion of myelin basic protein reactive T cells in patients with multiple sclerosis.
Academic Article Antigen-specific therapy for autoimmune disease.
Academic Article Weak peptide agonists reveal functional differences in B7-1 and B7-2 costimulation of human T cell clones.
Academic Article The TIGIT/CD226 axis regulates human T cell function.
Academic Article TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines.
Academic Article Activated CD8+ T cells in secondary progressive MS secrete lymphotoxin.
Academic Article In vitro evidence that immunuaffinity-purified MOG contains immunogenic quantities of contaminating mouse IgG; techniques for producing Ig-free MOG.
Academic Article T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis.
Academic Article PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells.
Academic Article Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand.
Academic Article Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis.
Concept Cytokines
Academic Article The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans.
Academic Article Small-molecule ROR?t antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
Academic Article Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.
Academic Article Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults.
Academic Article Genetic variants associated with autoimmunity drive NF?B signaling and responses to inflammatory stimuli.
Academic Article Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.
Academic Article Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.
Academic Article AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease.
Academic Article Podoplanin is a negative regulator of Th17 inflammation.
Academic Article Regulatory T Cells: From Discovery to Autoimmunity.
Academic Article Unsupervised capture and profiling of rare immune cells using multi-directional magnetic ratcheting.
Search Criteria
  • Cytokines
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.