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One or more keywords matched the following items that are connected to Hafler, David
Item TypeName
Academic Article CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.
Academic Article Differential responses of invariant V alpha 24J alpha Q T cells and MHC class II-restricted CD4+ T cells to dexamethasone.
Academic Article T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions.
Academic Article An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells.
Academic Article Frequency analysis of CD4+CD8+ T cells cloned with IL-4.
Academic Article Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation.
Academic Article Anti-CD4 and anti-CD2 monoclonal antibody infusions in subjects with multiple sclerosis. Immunosuppressive effects and human antimouse responses.
Academic Article The B7-CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system.
Academic Article Early signaling defects in human T cells anergized by T cell presentation of autoantigen.
Academic Article Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.
Academic Article Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation.
Academic Article Immunologic effects of cyclophosphamide/ACTH in patients with chronic progressive multiple sclerosis.
Academic Article CTLA-4 dysregulation in the activation of myelin basic protein reactive T cells may distinguish patients with multiple sclerosis from healthy controls.
Academic Article Regulation of T cell clone function via CD4 and CD8 molecules. Anti-CD4 can mediate two distinct inhibitory activities.
Academic Article Increased protein kinase C activity in human memory T cells.
Academic Article Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis.
Academic Article The CD6 multiple sclerosis susceptibility allele is associated with alterations in CD4+ T cell proliferation.
Academic Article CD4+CD25high regulatory cells in human peripheral blood.
Academic Article Anti-CD4 and anti-CD2 monoclonal antibody infusions in subjects with multiple sclerosis. Immunosuppressive effects and human anti-mouse responses.
Academic Article Sequestration of virus-specific T cells in the cerebrospinal fluid of a patient with varicella zoster viral meningoencephalitis.
Academic Article Lymphokine regulation of CD45R expression on human T cell clones.
Academic Article The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions.
Academic Article Phosphorylation of CD4 and CD8 molecules following T cell triggering.
Academic Article B7.2 expressed by T cells does not induce CD28-mediated costimulatory activity but retains CTLA4 binding: implications for induction of antitumor immunity to T cell tumors.
Academic Article GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.
Academic Article CTLA4 is associated with susceptibility to multiple sclerosis.
Academic Article T-T cell interactions are mediated by adhesion molecules.
Academic Article Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
Academic Article Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells.
Academic Article Inflammatory cerebrospinal fluid T cells have activation requirements characteristic of CD4+CD45RA- T cells.
Academic Article Mechanisms of immune memory. T cell activation and CD3 phosphorylation correlates with Ta1 (CDw26) expression.
Academic Article The TIGIT/CD226 axis regulates human T cell function.
Academic Article Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population.
Academic Article Presentation of autoantigen by human T cells.
Academic Article Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.
Academic Article FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation.
Academic Article Allelic variant in CTLA4 alters T cell phosphorylation patterns.
Academic Article Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis.
Academic Article Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells.
Academic Article Loss of functional suppression is linked to decreases in circulating suppressor-inducer (CD4+ 2H4+) T cells in multiple sclerosis.
Academic Article Strength of prior stimuli determines the magnitude of secondary responsiveness in CD8+ T cells.
Academic Article Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.
Concept Antigens, Differentiation, B-Lymphocyte
Concept Antigens, Differentiation, T-Lymphocyte
Concept Antigens, Differentiation
Academic Article The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans.
Academic Article The Link Between CD6 and Autoimmunity: Genetic and Cellular Associations.
Search Criteria
  • Antigens Differentiation
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.