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Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras.
Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras.
BLT humanized mice as model to study HIV vaginal transmission.
TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice.
Chemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa.