Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Szostak, Jack
Item TypeName
Academic Article RNA aptamers that bind flavin and nicotinamide redox cofactors.
Academic Article Isolation of high-affinity GTP aptamers from partially structured RNA libraries.
Academic Article Informational complexity and functional activity of RNA structures.
Academic Article Isolation of a fluorophore-specific DNA aptamer with weak redox activity.
Academic Article Stereochemical course of catalysis by the Tetrahymena ribozyme.
Academic Article Kinetic and thermodynamic characterization of the reaction catalyzed by a polynucleotide kinase ribozyme.
Academic Article Single-molecule binding experiments on long time scales.
Academic Article Aptamers selected for higher-affinity binding are not more specific for the target ligand.
Academic Article The guanosine binding site of the Tetrahymena ribozyme.
Academic Article Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.
Academic Article Suppression of mutations in the core of the Tetrahymena ribozyme by spermidine, ethanol and by substrate stabilization.
Academic Article Solution structure of an informationally complex high-affinity RNA aptamer to GTP.
Academic Article Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function.
Academic Article Evidence that the guanosine substrate of the Tetrahymena ribozyme is bound in the anti conformation and that N7 contributes to binding.
Academic Article Enzymatic activity of the conserved core of a group I self-splicing intron.
Concept Guanosine Triphosphate
Concept Guanosine
Concept Guanosine 5'-O-(3-Thiotriphosphate)
Grant RIBOZYME-SUBSTRATE INTERACTIONS
Academic Article Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension.
Academic Article Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer-Template Complexes.
Academic Article Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Academic Article Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.
Academic Article Template-Directed Nonenzymatic Primer Extension Using 2-Methylimidazole-Activated Morpholino Derivatives of Guanosine and Cytidine.
Search Criteria
  • Guanosine
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.