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One or more keywords matched the following items that are connected to Selkoe, Dennis
Item TypeName
Academic Article The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.
Academic Article Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease.
Academic Article Altered fatty acid composition of dopaminergic neurons expressing alpha-synuclein and human brains with alpha-synucleinopathies.
Academic Article Dopamine covalently modifies and functionally inactivates parkin.
Academic Article The monoclonal antibody, Alz 50, recognizes tau proteins in Alzheimer's disease brain.
Academic Article Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening.
Academic Article Identification of amyloid beta protein in the brain of the small, short-lived lemurian primate Microcebus murinus.
Academic Article Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing.
Academic Article The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.
Academic Article Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease.
Academic Article New insights on the composition of neurofilaments.
Academic Article Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin.
Academic Article Amyloid protein in Alzheimer's disease.
Academic Article Lack of specific association of presenilin 1 (PS-1) protein with plaques and tangles in Alzheimer's disease.
Academic Article Isolation of paired helical filaments and amyloid fibers from human brain.
Academic Article High molecular weight microtubule-associated proteins: purification by electro-elution and amino acid compositions.
Academic Article Aging, amyloid, and Alzheimer's disease: a perspective in honor of Carl Cotman.
Academic Article Isolation of hamster brain astroglia by in vitro cultivation and subcutaneous growth, and content of cerebroside, ganglioside, RNA and DNA.
Academic Article A seed for Alzheimer amyloid in the brain.
Academic Article Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.
Academic Article Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.
Academic Article Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins.
Academic Article Characterization of postmortem human brain proteins by two-dimensional gel electrophoresis.
Academic Article Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.
Academic Article Aging, amyloid, and Alzheimer's disease.
Academic Article Disease-related protein changes in purified neurons from Alzheimer's and Huntington's diseases.
Concept Brain Chemistry
Concept Chemistry, Pharmaceutical
Academic Article Purification of a-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity.
Grant LEADERSHIP AND EXCELLENCE IN ALZHEIMERS DISEASE
Grant Presenilin Biology and the Mechanisms of Alzheimer's Disease
Academic Article Large Soluble Oligomers of Amyloid ß-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
Academic Article A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aß oligomers from Alzheimer's brain.
Search Criteria
  • Chemistry
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.