Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Seaman, Michael
Item TypeName
Academic Article Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Academic Article Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Academic Article The neutralization properties of a HIV-specific antibody are markedly altered by glycosylation events outside the antigen-binding domain.
Academic Article PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.
Academic Article Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.
Academic Article Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein.
Concept Binding Sites, Antibody
Academic Article Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1.
Academic Article Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
Academic Article Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys.
Academic Article Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity.
Academic Article Combination therapy with anti-HIV-1 antibodies maintains viral suppression.
Academic Article Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement.
Search Criteria
  • Binding Sites Antibody
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.