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One or more keywords matched the following items that are connected to Neale, Benjamin
Item TypeName
Academic Article Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics.
Academic Article Genome-wide association study of response to methylphenidate in 187 children with attention-deficit/hyperactivity disorder.
Academic Article The positives, protocols, and perils of genome-wide association.
Academic Article Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.
Academic Article Genome-wide association scan of attention deficit hyperactivity disorder.
Academic Article Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Academic Article Runs of homozygosity implicate autozygosity as a schizophrenia risk factor.
Academic Article Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.
Academic Article Case-control genome-wide association study of attention-deficit/hyperactivity disorder.
Academic Article Genome-wide association study in German patients with attention deficit/hyperactivity disorder.
Academic Article Two independent alleles at 6q23 associated with risk of rheumatoid arthritis.
Academic Article Genome-wide association study of blood pressure response to methylphenidate treatment of attention-deficit/hyperactivity disorder.
Academic Article Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.
Academic Article Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
Academic Article A mega-analysis of genome-wide association studies for major depressive disorder.
Academic Article Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
Academic Article PLINK: a tool set for whole-genome association and population-based linkage analyses.
Academic Article Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Academic Article A genome scan of neuroticism in nicotine dependent smokers.
Academic Article Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
Academic Article Genome-wide association study identifies five new schizophrenia loci.
Academic Article Practical aspects of imputation-driven meta-analysis of genome-wide association studies.
Academic Article Extremely low-coverage sequencing and imputation increases power for genome-wide association studies.
Academic Article Genome-wide association studies in ADHD.
Academic Article On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls.
Academic Article Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.
Academic Article Genetic profile for five common variants associated with age-related macular degeneration in densely affected families: a novel analytic approach.
Academic Article Genome-wide association study of obsessive-compulsive disorder.
Academic Article Meta-analysis of genome-wide association studies.
Academic Article Non-random error in genotype calling procedures: implications for family-based and case-control genome-wide association studies.
Academic Article Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
Academic Article Perspective on the genetics of attention deficit/hyperactivity disorder.
Academic Article Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder.
Academic Article Common variants at CD40 and other loci confer risk of rheumatoid arthritis.
Academic Article Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
Academic Article Pervasive sharing of genetic effects in autoimmune disease.
Academic Article Genome-wide association study of Tourette's syndrome.
Concept Genome-Wide Association Study
Concept Genome
Concept Genome, Human
Concept Human Genome Project
Academic Article Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants.
Academic Article Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Academic Article Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
Academic Article Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls.
Academic Article Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
Academic Article Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
Academic Article Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample.
Academic Article Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
Academic Article Searching for missing heritability: designing rare variant association studies.
Academic Article An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases.
Academic Article Statistical properties of single-marker tests for rare variants.
Academic Article Whole-genome analyses of whole-brain data: working within an expanded search space.
Academic Article Copy number variation in schizophrenia in Sweden.
Academic Article Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
Academic Article Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Academic Article Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children.
Academic Article Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Academic Article Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
Academic Article Efficient Bayesian mixed-model analysis increases association power in large cohorts.
Academic Article LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Academic Article Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation.
Academic Article The genetics of neuropsychiatric diseases: looking in and beyond the exome.
Academic Article Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Academic Article An atlas of genetic correlations across human diseases and traits.
Academic Article Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Academic Article Partitioning heritability by functional annotation using genome-wide association summary statistics.
Academic Article Genetic research in autism spectrum disorders.
Academic Article Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.
Academic Article New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
Academic Article Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
Academic Article Exome arrays capture polygenic rare variant contributions to schizophrenia.
Academic Article Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
Academic Article The statistical properties of gene-set analysis.
Academic Article Phenotypic extremes in rare variant study designs.
Academic Article Genome-wide autozygosity is associated with lower general cognitive ability.
Academic Article Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers.
Academic Article Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
Academic Article The genetic architecture of type 2 diabetes.
Grant Center for Genome Interpretation
Grant Powering whole genome sequence-based genetic discovery for common human diseases
Grant Quantifying the impact of rare mutations on ADHD
Grant Statistical methods to localize disease heritability and identify biological mechanisms
Grant Harvard Reproductive Endocrine Sciences Center
Academic Article A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts.
Academic Article Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Academic Article No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study.
Academic Article A framework for the detection of de novo mutations in family-based sequencing data.
Academic Article LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.
Academic Article ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties.
Academic Article Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Academic Article The Weighting is the Hardest Part: On the Behavior of the Likelihood Ratio Test and the Score Test Under a Data-Driven Weighting Scheme in Sequenced Samples.
Academic Article Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
Academic Article Phenome-wide heritability analysis of the UK Biobank.
Academic Article Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.
Academic Article Quantifying the Genetic Correlation between Multiple Cancer Types.
Academic Article Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
Academic Article Polygenic risk for schizophrenia and neurocognitive performance in patients with schizophrenia.
Academic Article Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia.
Academic Article Whole genome sequencing in psychiatric disorders: the WGSPD consortium.
Academic Article Multi-trait analysis of genome-wide association summary statistics using MTAG.
Academic Article Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.
Academic Article A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.
Academic Article Publisher Correction: Whole genome sequencing in psychiatric disorders: the WGSPD consortium.
Academic Article Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.
Academic Article Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
Academic Article An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.
Academic Article Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.
Academic Article Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families.
Academic Article Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
Academic Article Base-specific mutational intolerance near splice sites clarifies the role of nonessential splice nucleotides.
Academic Article Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum.
Academic Article Analysis of shared heritability in common disorders of the brain.
Academic Article Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Academic Article A synthetic-diploid benchmark for accurate variant-calling evaluation.
Academic Article Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Academic Article Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.
Academic Article PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics.
Academic Article Large-scale meta-analysis highlights the hypothalamic-pituitary-gonadal axis in the genetic regulation of menstrual cycle length.
Academic Article Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects.
Academic Article Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
Academic Article Joint Contributions of Rare Copy Number Variants and Common SNPs to Risk for Schizophrenia.
Academic Article Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.
Academic Article Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.
Academic Article Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.
Academic Article GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology.
Academic Article Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder.
Academic Article Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.
Academic Article Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language.
Academic Article A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment.
Academic Article Genetic Markers of ADHD-Related Variations in Intracranial Volume.
Academic Article Identification of common genetic risk variants for autism spectrum disorder.
Academic Article Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.
Academic Article Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies.
Academic Article Advanced Paternal Age and Early Onset of Schizophrenia in Sporadic Cases: Not Confounded by Parental Polygenic Risk for Schizophrenia.
Academic Article Predicting Polygenic Risk of Psychiatric Disorders.
Academic Article Clinical use of current polygenic risk scores may exacerbate health disparities.
Academic Article Genome-wide association study identifies 30 loci associated with bipolar disorder.
Academic Article Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG.
Academic Article Estimation of metabolic syndrome heritability in three large populations including full pedigree and genomic information.
Academic Article Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG.
Academic Article RICOPILI: Rapid Imputation for COnsortias PIpeLIne.
Academic Article A global overview of pleiotropy and genetic architecture in complex traits.
Academic Article Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior.
Grant Statistical methods to localize disease heritability and identify biological mechanisms
Academic Article International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Academic Article Comparative genetic architectures of schizophrenia in East Asian and European populations.
Academic Article Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.
Academic Article Genome studies must account for history-Response.
Academic Article Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Academic Article GWAS significance thresholds for deep phenotyping studies can depend upon minor allele frequencies and sample size.
Academic Article Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
Academic Article Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.
Academic Article A structural variation reference for medical and population genetics.
Academic Article Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics.
Academic Article The mutational constraint spectrum quantified from variation in 141,456 humans.
Academic Article Mapping and characterization of structural variation in 17,795 human genomes.
Academic Article Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Academic Article Genome-wide association study identifies 48 common genetic variants associated with handedness.
Academic Article The genetic architecture of sporadic and multiple consecutive miscarriage.
Academic Article Synaptic processes and immune-related pathways implicated in Tourette syndrome.
Academic Article Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.
Academic Article Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder.
Grant 1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries
Academic Article Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits.
Academic Article Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum.
Academic Article Low-coverage sequencing cost-effectively detects known and novel variation in underrepresented populations.
Academic Article Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior".
Academic Article Genetic analyses identify widespread sex-differential participation bias.
Academic Article Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.
Academic Article Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
Grant 2/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact
Academic Article Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection.
Academic Article Problems with Using Polygenic Scores to Select Embryos.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.