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One or more keywords matched the following items that are connected to Libby, Peter
Item TypeName
Academic Article Macrophages and atherosclerotic plaque stability.
Academic Article Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.
Academic Article The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach.
Academic Article Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques.
Academic Article Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling.
Academic Article Molecular determinants of atherosclerotic plaque vulnerability.
Academic Article Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability.
Academic Article Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression.
Academic Article Cytokines induce indoleamine 2,3-dioxygenase expression in human atheroma-asociated cells: implications for persistent Chlamydophila pneumoniae infection.
Academic Article Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm
Academic Article Cytokines induce indoleamine 2,3-dioxygenase expression in human atheroma-associated cells: implications for persistent Chlamydia pneumoniae infection
Academic Article Matrix metalloproteinases and their inhibitors
Academic Article Improved characterization of atherosclerotic plaques by gadolinium contrast during intravascular magnetic resonance imaging of human arteries.
Academic Article Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits.
Academic Article The unstable atheroma.
Academic Article Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.
Academic Article Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.
Academic Article Multiple mechanisms of thrombosis complicating atherosclerotic plaques.
Academic Article Evolution and stabilization of vulnerable atherosclerotic plaques.
Academic Article Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions.
Academic Article Selective inhibition of matrix metalloproteinase-13 increases collagen content of established mouse atherosclerosis.
Academic Article Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.
Academic Article Matrix-metalloproteinase-14 deficiency in bone-marrow-derived cells promotes collagen accumulation in mouse atherosclerotic plaques.
Academic Article Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques.
Academic Article The vulnerable atherosclerotic plaque: Understanding, identification, and modification. IV: Structure of cellular components of vulnerable plaque. "Inflammatory cells." [CD]
Academic Article Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.
Academic Article IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.
Academic Article Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal.
Academic Article Metalloproteinases and atherosclerotic plaque rupture
Academic Article Progression of atheroma: a struggle between death and procreation.
Academic Article Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol.
Academic Article Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Academic Article Non-invasive anatomic and functional imaging of vascular inflammation and unstable plaque.
Academic Article Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells.
Academic Article Stabilization of atherosclerotic plaques: new mechanisms and clinical targets.
Academic Article Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm: possible role for a feedback loop in endothelial cells.
Academic Article Evolution and stabilization of vulnerable atherosclerotic plaques [review]
Academic Article Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma.
Academic Article Tension in the plaque: hypoxia modulates metabolism in atheroma.
Academic Article TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.
Academic Article Molecular imaging of atherosclerosis for improving diagnostic and therapeutic development.
Academic Article Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques.
Academic Article Inflammation in atherosclerosis.
Academic Article Macrophages in human atheroma contain PPAR?: Differentiation-dependent peroxisomal proliferator-activated receptor ? (PPAR?) expression and reduction of MMP-9 activity through PPAR? activation in mononuclear phagocytes in vitro
Academic Article "Modifying approaches" [CD]. (Includes video) Scientific Conference: Assessing and Modifying the Vulnerable Atherosclerotic Plaque
Academic Article Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs.
Academic Article Impact of statins on progression of atherosclerosis: rationale and design of SATURN (Study of Coronary Atheroma by InTravascular Ultrasound: effect of Rosuvastatin versus AtorvastatiN).
Academic Article Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study using high-resolution MRI
Academic Article Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma.
Academic Article Atheroma: more than mush.
Academic Article Atheromas that cause fatal thrombosis are usually large and frequently accompanied by vessel enlargement.
Academic Article Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro.
Academic Article Regulation of the thrombotic potential of atheroma.
Academic Article The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques.
Academic Article Lipid lowering reduces proteolytic and prothrombotic potential in rabbit atheroma.
Academic Article Multiple mechanisms of thrombosis complicating atherosclerotic plaques
Academic Article The increasing significance of the unstable atheroma
Academic Article Molecular determinants of atherosclerotic plaque vulnerability
Academic Article Potential mechanisms of atherosclerotic plaque stabilization by lipid lowering
Academic Article Neutrophil elastase in human atherosclerotic plaques: production by macrophages.
Academic Article Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques.
Academic Article The vulnerable atherosclerotic plaque: Understanding, identification, and modification. Session VI: Functional components of the vulnerable plaque. "Metalloproteinases and TIMP proteins." [CD]
Academic Article Atherosclerotic plaque inflammation: the final frontier?
Academic Article Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging.
Academic Article Comparison between adventitial and intimal inflammation of ruptured and nonruptured atherosclerotic plaques in human coronary arteries.
Academic Article Natural history of an atheroma [animated video]
Academic Article T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice.
Academic Article Visualizing the vascular glue "shearing" the barriers to atherosclerotic plaque imaging.
Academic Article Diversity of T-cell antigen receptor V beta gene utilization in advanced human atheroma.
Academic Article Stabilization of atherosclerotic plaques [in Japanese]
Academic Article Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme.
Academic Article Adiponectin induces pro-inflammatory programs in human macrophages and CD4+ T cells.
Academic Article Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques.
Academic Article Cytokines regulate vascular functions related to stability of the atherosclerotic plaque.
Academic Article Stabilization of the vulnerable atherosclerotic plaque [interview]
Academic Article Stabilization of the vulnerable atherosclerotic plaque [Interview with George A. Beller on audio tape]. 31(1):1
Academic Article Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma.
Academic Article The increasing significance of the unstable atheroma
Academic Article Dyslipidemia and atheroma in the young [commentary]
Academic Article Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma.
Academic Article Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages.
Academic Article Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRI.
Academic Article Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques.
Academic Article A role for chronic adventitial inflammation in positive arterial remodeling and atheroma instability
Academic Article Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma.
Academic Article Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.
Concept Plaque, Atherosclerotic
Academic Article Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress.
Academic Article Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques.
Academic Article Collagenases and cracks in the plaque.
Academic Article Factors underlying regression of coronary atheroma with potent statin therapy.
Academic Article Mechanisms of acute coronary syndromes and their implications for therapy.
Academic Article Mechanisms of acute coronary syndromes.
Academic Article Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy.
Academic Article C-reactive protein, but not low-density lipoprotein cholesterol levels, associate with coronary atheroma regression and cardiovascular events after maximally intensive statin therapy.
Academic Article Long-term effects of maximally intensive statin therapy on changes in coronary atheroma composition: insights from SATURN.
Academic Article Matrix metalloproteinase-13 predominates over matrix metalloproteinase-8 as the functional interstitial collagenase in mouse atheromata.
Academic Article Inflammation goes with the flow: implications for non-invasive identification of high-risk plaque.
Academic Article Inflammation and its resolution as determinants of acute coronary syndromes.
Academic Article Antiatherosclerotic effects of long-term maximally intensive statin therapy after acute coronary syndrome: insights from Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin.
Academic Article High-intensity statin therapy alters the natural history of diabetic coronary atherosclerosis: insights from SATURN.
Academic Article Increased microvascularization and vessel permeability associate with active inflammation in human atheromata.
Academic Article Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
Academic Article TLR2 and neutrophils potentiate endothelial stress, apoptosis and detachment: implications for superficial erosion.
Academic Article Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Academic Article Requiem for the 'vulnerable plaque'.
Academic Article Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques.
Academic Article Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.
Grant Inflammatory Mechanisms of Atherosclerosis
Grant CONTROL OF GROWTH OF VASCULAR WALL CELLS
Grant CRITICAL TRANSITIONS IN ATHEROGENESIS
Grant RESTENOSIS PATHOBIOLOGY--A CASCADE MECHANISM
Academic Article Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis: Clinical and Intracoronary Evaluation of Indocyanine Green.
Academic Article Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease.
Academic Article Seeing and Sampling the Surface of the Atherosclerotic Plaque: Red or White Can Make Blue.
Academic Article Superficial erosion and the precision management of acute coronary syndromes: not one-size-fits-all.
Academic Article Combined non-invasive assessment of endothelial shear stress and molecular imaging of inflammation for the prediction of inflamed plaque in hyperlipidaemic rabbit aortas.
Academic Article Assisted Living in the Atheroma: Elderly Macrophages Promote Plaques.
Academic Article Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging.
Academic Article Lipoprotein(a) and coronary atheroma progression rates during long-term high-intensity statin therapy: Insights from SATURN.
Academic Article Mechanisms of erosion of atherosclerotic plaques.
Academic Article Acute Coronary Syndromes: The Way Forward From Mechanisms to Precision Treatment.
Academic Article Coronary Plaque Microstructure and Composition Modify Optical Polarization: A New Endogenous Contrast Mechanism for Optical Frequency Domain Imaging.
Academic Article Plaque erosion: a new in vivo diagnosis and a potential major shift in the management of patients with acute coronary syndromes.
Academic Article Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture: A 3-Vessel Optical Coherence Tomography Study.
Academic Article Pleiotropic Anti-atherosclerotic Effects of PCSK9 InhibitorsFrom Molecular Biology to Clinical Translation.
Academic Article Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion.
Academic Article Jak-ing Up the Plaque's Lipid Core…and Even More.
Academic Article Reassessing the Mechanisms of Acute Coronary Syndromes.
Academic Article Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery.
Academic Article Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.
Academic Article Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology.
Academic Article Fluorodeoxyglucose Uptake in Atheroma: Not So Simple.
Academic Article Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.
Academic Article Linking regulation of nitric oxide to endothelin-1: The Yin and Yang of vascular tone in the atherosclerotic plaque.
Academic Article Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease.
Academic Article Neutrophil Extracellular Traps Participate in Cardiovascular Diseases: Recent Experimental and Clinical Insights.
Academic Article Editorial commentary: Arson in the artery: Who set the atheroma aflame?
Academic Article S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus.
Academic Article Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans.
Academic Article New Insights Into Plaque Erosion as a Mechanism of Acute Coronary Syndromes.
Academic Article Near-Infrared Autofluorescence in Atherosclerosis Associates With Ceroid and Is Generated by Oxidized Lipid-Induced Oxidative Stress.
Academic Article Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Academic Article Resilience of the Internal Mammary Artery to Atherogenesis: Shifting From Risk to Resistance to Address Unmet Needs.
Academic Article Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.
Academic Article Inflammation during the life cycle of the atherosclerotic plaque.
Search Criteria
  • Plaque Atherosclerotic
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.