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One or more keywords matched the following items that are connected to Church, George
Item TypeName
Academic Article Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae.
Academic Article Genomic studies with Escherichia coli MelR protein: applications of chromatin immunoprecipitation and microarrays.
Academic Article Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae.
Academic Article The complete genome and proteome of Mycoplasma mobile.
Academic Article Sequencing genomes from single cells by polymerase cloning.
Academic Article Selection analyses of insertional mutants using subgenic-resolution arrays.
Academic Article Programming cells by multiplex genome engineering and accelerated evolution.
Academic Article Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation.
Academic Article Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation.
Academic Article Predicting regulons and their cis-regulatory motifs by comparative genomics.
Academic Article Multiplex sequencing of 1.5 Mb of the Mycobacterium leprae genome.
Academic Article Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset.
Academic Article A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete Escherichia coli K-12 genome.
Academic Article Phased whole-genome genetic risk in a family quartet using a major allele reference sequence.
Academic Article Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae.
Academic Article From genetic privacy to open consent.
Academic Article Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes.
Academic Article RNA expression analysis using a 30 base pair resolution Escherichia coli genome array.
Academic Article Identifying metabolic enzymes with multiple types of association evidence.
Academic Article A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli.
Academic Article Assaying chromosomal inversions by single-molecule haplotyping.
Academic Article Towards synthesis of a minimal cell.
Academic Article Multiplex amplification of large sets of human exons.
Academic Article A whole genome approach to in vivo DNA-protein interactions in E. coli.
Academic Article Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Academic Article Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli.
Academic Article Genomes optimize reproduction: aging as a consequence of the developmental program.
Academic Article Genomes for all.
Academic Article The personal genome project.
Academic Article Synthetic biology projects in vitro.
Academic Article Patterns and implications of gene gain and loss in the evolution of Prochlorococcus.
Academic Article Public access to genome-wide data: five views on balancing research with privacy and protection.
Academic Article The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Academic Article Genome-scale promoter engineering by coselection MAGE.
Academic Article Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays.
Academic Article Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites.
Academic Article A motif co-occurrence approach for genome-wide prediction of transcription-factor-binding sites in Escherichia coli.
Academic Article Discovering functional transcription-factor combinations in the human cell cycle.
Academic Article A highly annotated whole-genome sequence of a Korean individual.
Academic Article Systematic identification of edited microRNAs in the human brain.
Academic Article Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection.
Academic Article Proteogenomic mapping as a complementary method to perform genome annotation.
Academic Article Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.
Academic Article Genome engineering.
Academic Article Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering.
Academic Article Personal genomes in progress: from the human genome project to the personal genome project.
Academic Article Autoantigen discovery with a synthetic human peptidome.
Academic Article Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions.
Academic Article RNA-guided human genome engineering via Cas9.
Academic Article Reading and writing omes.
Academic Article Back to the future: from genome to metabolome.
Academic Article Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution.
Academic Article Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing.
Academic Article A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.
Academic Article Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering.
Academic Article Systematic management and analysis of yeast gene expression data.
Academic Article A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression.
Academic Article Computational discovery of sense-antisense transcription in the human and mouse genomes.
Academic Article Identification of foreign gene sequences by transcript filtering against the human genome.
Academic Article A network of transcriptionally coordinated functional modules in Saccharomyces cerevisiae.
Academic Article Computational comparison of two draft sequences of the human genome.
Academic Article Advanced sequencing technologies: methods and goals.
Academic Article Evidence for large diversity in the human transcriptome created by Alu RNA editing.
Academic Article Barcoding bias in high-throughput multiplex sequencing of miRNA.
Academic Article Genomic analysis of the hydrocarbon-producing, cellulolytic, endophytic fungus Ascocoryne sarcoides.
Academic Article Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells.
Academic Article Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.
Academic Article Clinical assessment incorporating a personal genome.
Academic Article Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model.
Academic Article From annotated genomes to metabolic flux models and kinetic parameter fitting.
Academic Article Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases.
Academic Article How accurate can genetic predictions be?
Academic Article The most conserved genome segments for life detection on Earth and other planets.
Academic Article Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.
Academic Article The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting.
Academic Article A public resource facilitating clinical use of genomes.
Academic Article Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution.
Academic Article Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.
Academic Article Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems.
Academic Article Accurate multiplex polony sequencing of an evolved bacterial genome.
Academic Article A proposal to sequence genomes of unique interest for research on aging.
Academic Article Large-scale identification of genetic design strategies using local search.
Academic Article Life after the synthetic cell.
Academic Article Genome-scale metabolic model of Helicobacter pylori 26695.
Academic Article More Haemophilus and Mycoplasma genes.
Academic Article Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization.
Academic Article The amino-acid mutational spectrum of human genetic disease.
Academic Article Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells.
Concept Genome, Plant
Concept Genome-Wide Association Study
Concept Genome, Archaeal
Concept Genome
Concept Genome, Human
Concept Genome, Helminth
Concept Human Genome Project
Concept Genome, Fungal
Concept Genome, Viral
Concept Genome, Bacterial
Academic Article Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.
Academic Article Heritable genome editing in C. elegans via a CRISPR-Cas9 system.
Academic Article CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.
Academic Article Optimization of scarless human stem cell genome editing.
Academic Article Cas9 as a versatile tool for engineering biology.
Academic Article Improving genome understanding.
Academic Article Probing the limits of genetic recoding in essential genes.
Academic Article Genomically recoded organisms expand biological functions.
Academic Article Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system.
Academic Article The role of replicates for error mitigation in next-generation sequencing.
Academic Article CRISPR-Cas-mediated targeted genome editing in human cells.
Academic Article Rational optimization of tolC as a powerful dual selectable marker for genome engineering.
Academic Article Genome interpretation and assembly-recent progress and next steps.
Academic Article Next-generation carrier screening.
Academic Article Yeast oligo-mediated genome engineering (YOGE).
Academic Article CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing.
Academic Article CRISPR/Cas9-Directed Genome Editing of Cultured Cells.
Academic Article On the design of clone-based haplotyping.
Academic Article Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).
Academic Article Genome editing in human stem cells.
Academic Article Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.
Academic Article Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes.
Academic Article The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.
Academic Article Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68.
Academic Article Insights into the evolution of longevity from the bowhead whale genome.
Academic Article Genome and Transcriptome of Clostridium phytofermentans, Catalyst for the Direct Conversion of Plant Feedstocks to Fuels.
Academic Article Accurate whole genome sequencing as the ultimate genetic test.
Academic Article Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides.
Academic Article Biotechnology. A prudent path forward for genomic engineering and germline gene modification.
Academic Article Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.
Academic Article Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.
Academic Article BIOSAFETY. Safeguarding gene drive experiments in the laboratory.
Academic Article Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach.
Academic Article Genome-wide inactivation of porcine endogenous retroviruses (PERVs).
Academic Article Cas9 gRNA engineering for genome editing, activation and repression.
Academic Article Perspective: Encourage the innovators.
Academic Article Tools for the Microbiome: Nano and Beyond.
Academic Article Molecular recordings by directed CRISPR spacer acquisition.
Academic Article Extensive sequencing of seven human genomes to characterize benchmark reference materials.
Academic Article GENOME ENGINEERING. The Genome Project-Write.
Academic Article Design, synthesis, and testing toward a 57-codon genome.
Grant A Tolerance Approach to Xenotransplantation
Grant Molecular and Genomic Imaging Center
Grant Causal Transcriptional Consequences of Human Genetic Variation
Grant An Integrated System for Single Molecule Electronic Sequencing by Synthesis
Grant Genome Engineering an IPSC Model of Alzheimer's Disease
Grant Recording neural activities onto DNA
Grant Development of Electron Microscopy-based Nucleic Acid Polymer Sequencing
Grant SINGLE CHANNEL DNA SEQUENCING
Grant Center for Genomically Engineered Organs
Grant Targeted 2nd generation sequencing in phenotyped Framingham &PGP populations.
Academic Article Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli.
Grant Exploring a Novel Paradigm of Schizophrenia and Bipolar Disorder
Academic Article The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes.
Academic Article Engineering and optimising deaminase fusions for genome editing.
Academic Article An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes.
Academic Article Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies.
Academic Article An unbiased index to quantify participant's phenotypic contribution to an open-access cohort.
Academic Article Optimizing complex phenotypes through model-guided multiplex genome engineering.
Academic Article Millstone: software for multiplex microbial genome analysis and engineering.
Academic Article CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria.
Academic Article Beyond editing to writing large genomes.
Academic Article The Future of Multiplexed Eukaryotic Genome Engineering.
Academic Article From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies.
Academic Article Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration.
Academic Article Adaptive evolution of genomically recoded Escherichia coli.
Academic Article An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.
Academic Article Enabling multiplexed testing of pooled donor cells through whole-genome sequencing.
Grant Single-Molecule Electronic Nucleic Acid Sequencing-by-Synthesis Using Novel Tagged Nucleotides and Nanopore Constructs
Grant Single-Molecule Electronic Nucleic Acid Sequencing-by-Synthesis Using Novel Tagged Nucleotides and Nanopore Constructs
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.