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Proliferating cell nuclear antigen uses two distinct modes to move along DNA.
Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay.
Single-molecule studies of the replisome.
Real-time single-molecule observation of rolling-circle DNA replication.
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis.
Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange.
DNA-Directed DNA Polymerase
Mapping DNA polymerase errors by single-molecule sequencing.
Single-molecule imaging reveals multiple pathways for the recruitment of translesion polymerases after DNA damage.
A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes.
Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock.
Validating a potential interaction between error-prone polymerases and SSB as a therapeutic target for Mycobacterium tuberculosis
DNA Directed DNA Polymerase