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One or more keywords matched the following items that are connected to Knipe, David
Item TypeName
Academic Article Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
Academic Article Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression.
Academic Article Type 3 reovirus neuroinvasion after intramuscular inoculation: direct invasion of nerve terminals and age-dependent pathogenesis.
Academic Article C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization.
Academic Article An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection.
Academic Article Herpes simplex virus.
Academic Article Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells.
Academic Article Replication-defective viruses as vaccines and vaccine vectors.
Academic Article Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
Academic Article Immunization with a replication-deficient mutant of herpes simplex virus type 1 (HSV-1) induces a CD8+ cytotoxic T-lymphocyte response and confers a level of protection comparable to that of wild-type HSV-1.
Academic Article Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation.
Academic Article Effect of immunization on herpes simplex virus type 1 latent infection in the trigeminal ganglion.
Academic Article A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression.
Academic Article The role of viral and cellular nuclear proteins in herpes simplex virus replication.
Academic Article Assembly of herpes simplex virus replication proteins at two distinct intranuclear sites.
Academic Article Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation.
Academic Article The use of green fluorescent fusion proteins to monitor herpes simplex virus replication.
Academic Article Separate pathways of maturation of the major structural proteins of vesicular stomatitis virus.
Academic Article Viral replication is required for induction of ocular immunopathology by herpes simplex virus.
Academic Article Comparative efficacy and immunogenicity of replication-defective, recombinant glycoprotein, and DNA vaccines for herpes simplex virus 2 infections in mice and guinea pigs.
Academic Article Contributions of antibody and T cell subsets to protection elicited by immunization with a replication-defective mutant of herpes simplex virus type 1.
Academic Article Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge.
Academic Article Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model.
Academic Article Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.
Academic Article Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression.
Academic Article Mechanism of virus-induced Ig subclass shifts.
Academic Article Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.
Academic Article Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA.
Academic Article CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2.
Academic Article Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection.
Academic Article Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach.
Academic Article Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity.
Academic Article Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production.
Academic Article Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus.
Academic Article Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.
Academic Article Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures.
Academic Article Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.
Academic Article Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes.
Academic Article Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress.
Academic Article Simian TRIM5alpha proteins reduce replication of herpes simplex virus.
Academic Article Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gene expression and replication.
Academic Article Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein.
Academic Article Cell growth transformation by herpes simplex virus.
Academic Article Replication-defective mutants of herpes simplex virus (HSV) induce cellular immunity and protect against lethal HSV infection.
Academic Article Nucleotide sequence complexities, molecular weights, and poly(A) content of the vesicular stomatitis virus mRNA species.
Academic Article Identification of a divalent metal cation binding site in herpes simplex virus 1 (HSV-1) ICP8 required for HSV replication.
Academic Article Immunization against genital herpes with a vaccine virus that has defects in productive and latent infection.
Academic Article Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells.
Academic Article Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus.
Academic Article Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease.
Academic Article Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.
Academic Article Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
Academic Article Herpes simplex virus 1 U(L)31 and U(L)34 gene products promote the late maturation of viral replication compartments to the nuclear periphery.
Academic Article Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis.
Academic Article Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes.
Academic Article Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Academic Article Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses.
Academic Article Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
Academic Article Snapshots: chromatin control of viral infection.
Academic Article The acidic amino-terminal region of herpes simplex virus type 1 alpha protein ICP27 is required for an essential lytic function.
Academic Article On the structure, functional equivalence, and replication of the four arrangements of herpes simplex virus DNA.
Academic Article The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication.
Academic Article Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication.
Academic Article Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.
Academic Article Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2.
Academic Article Herpes simplex virus thymidine kinase and specific stages of latency in murine trigeminal ganglia.
Academic Article Herpes simplex virus replication compartments can form by coalescence of smaller compartments.
Concept Virus Replication
Academic Article HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses.
Academic Article Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.
Academic Article Identification of TRIM27 as a novel degradation target of herpes simplex virus 1 ICP0.
Academic Article HSV-1 remodels host telomeres to facilitate viral replication.
Academic Article Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses.
Academic Article Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.
Academic Article Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity.
Academic Article Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus.
Grant Nuclear Sensing of Herpesviral DNA
Academic Article A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.
Academic Article Role of Herpes Simplex Virus 1 ?34.5 in the Regulation of IRF3 Signaling.
Academic Article Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication.
Academic Article Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection.
Academic Article Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9.
Search Criteria
  • Virus Replication
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.