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One or more keywords matched the following items that are connected to Margolies, Michael
Item TypeName
Academic Article A V kappa-J kappa junctional change in an antidigoxin recombinant antibody destroys digoxin-binding activity.
Academic Article Isolation and characterization of an active variable domain from a homogeneous rabbit antibody light chain.
Academic Article Selection of peptidic mimics of digoxin from phage-displayed peptide libraries by anti-digoxin antibodies.
Academic Article Modifying specificity of antidigoxin antibodies using insertional mutagenesis.
Academic Article Monoclonal antibodies that distinguish between two related digitalis glycosides, ouabain and digoxin.
Academic Article Recurrent somatic mutations in mouse antibodies to p-azophenylarsonate increase affinity for hapten.
Academic Article Complete heavy and light chain variable region sequence of anti-arsonate monoclonal antibodies from BALB/c and A/J mice sharing the 36-60 idiotype are highly homologous.
Academic Article Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.
Academic Article Immunoglobulin idiotype and anti-anti-idiotype utilize the same variable region genes irrespective of antigen specificity.
Academic Article Effect of heavy chain signal peptide mutations and NH2-terminal chain length on binding of anti-digoxin antibodies.
Academic Article Conservation of binding site geometry among p-azophenylarsonate-specific antibodies.
Academic Article The structural basis of rabbit VH allotypes: serologic studies on a1 H chains with defined amino acid sequence.
Academic Article Antibody binding sites.
Academic Article Purification, specificity, and hypervariable region sequence of anti-pneumococcal polysaccharide antibodies elicited in a single rabbit.
Academic Article Origins of antibody diversity: insight gained from amino acid sequence studies of elicited antibodies.
Academic Article Fine specificity of idiotope suppression in the A/J anti-azophenylarsonate response.
Academic Article Diversity of light chain variable region sequences among rabbit antibodies elicited by the same antigens.
Academic Article Immunoglobulin chain recombination among antidigoxin antibodies by hybridoma-hybridoma fusion.
Academic Article Defining the structural correlates responsible for loss of arsonate affinity in an IDCR antibody isolated from an autoimmune mouse.
Academic Article Isolation of an active heavy-chain variable domain from a homogeneous rabbit antibody by cathepsin B digestion of the aminoethylated heavy chain.
Academic Article 26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
Academic Article Modulation of antibody affinity by a non-contact residue.
Concept Binding Sites, Antibody
Search Criteria
  • Binding Sites Antibody
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.