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Item TypeName
Academic Article Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements.
Academic Article The immunopathogenesis of retroviral diseases: no immunophenotypic alterations in T, B, and NK cell subsets in SIVmac239-challenged rhesus macaques protected by SIV delta nef vaccination.
Academic Article A case of pulmonary cestodiasis in a simian immunodeficiency virus-infected pigtailed macaque (Macaca nemestrina) in which virus-infected leukocytes are present within the lesion.
Academic Article Identification of highly attenuated mutants of simian immunodeficiency virus.
Academic Article Prospects for live attenuated HIV.
Academic Article A caution on the use of SIV/HIV gag antigen detection systems in neutralization assays.
Academic Article Production and characterization of SIV envelope-specific rhesus monoclonal antibodies from a macaque asymptomatically infected with a live SIV vaccine.
Academic Article Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys.
Academic Article The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus.
Academic Article Use of lentivirus-like particles alone and in combination with live vaccinia-virus-based vaccines.
Academic Article HIV with multiple gene deletions as a live attenuated vaccine for AIDS.
Academic Article Effects of reverse-transcriptase mutations M184V and E89G on simian immunodeficiency virus in Rhesus monkeys.
Academic Article Nef genes of SIV.
Academic Article AIDS biosafety.
Academic Article Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques.
Academic Article HIV vaccine design and the neutralizing antibody problem.
Academic Article A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120.
Academic Article Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.
Academic Article AIDS vaccine developments.
Academic Article Protective immunity induced by live attenuated simian immunodeficiency virus.
Academic Article Recombinant simian immunodeficiency virus expressing green fluorescent protein identifies infected cells in rhesus monkeys.
Academic Article Experimental infection of rhesus and pig-tailed macaques with macaque rhadinoviruses.
Academic Article Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
Academic Article Relative importance and functional role of genetic elements targeted for a live attenuated AIDS vaccine
Academic Article Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy.
Academic Article Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity.
Academic Article Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge.
Academic Article Importance of the nef gene for maintenance of high virus loads and for development of AIDS.
Academic Article The value of specific pathogen-free rhesus monkey breeding colonies for AIDS research.
Academic Article A role for carbohydrates in immune evasion in AIDS.
Academic Article Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys.
Academic Article An AIDS vaccine: no time to give up.
Academic Article Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection.
Academic Article Use of simian immunodeficiency virus for vaccine research.
Academic Article Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Academic Article Characterization of the cutaneous exanthem in macaques infected with a Nef gene variant of SIVmac239.
Academic Article Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
Academic Article Prevalence of antibodies to SIV in baboons in their native habitat.
Academic Article Sexual transmission of SIVagm in wild grivet monkeys.
Academic Article Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Academic Article Modulation of HIV and SIV neutralization sensitivity by DC-SIGN and mannose-binding lectin.
Academic Article High-titer immune responses elicited by recombinant vaccinia virus priming and particle boosting are ineffective in preventing virulent SIV infection.
Academic Article Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus.
Academic Article Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys.
Academic Article Comparison of simian immunodeficiency virus isolates.
Academic Article Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus.
Academic Article Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection.
Academic Article Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus.
Academic Article HIV-related lentiviruses of nonhuman primates.
Academic Article Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus.
Academic Article Progression to AIDS in the absence of a gene for vpr or vpx.
Academic Article Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS.
Academic Article Induction of AIDS in rhesus monkeys by a recombinant simian immunodeficiency virus expressing nef of human immunodeficiency virus type 1.
Academic Article Does the HIV-1deltakURNe vaccine strain hold the key to curbing HIV infection? An interview with Ronald Desrosiers, PhD.
Academic Article Prospects for an AIDS vaccine.
Academic Article CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity.
Academic Article Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesis.
Academic Article Chasing viruses.
Academic Article Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery.
Academic Article The use of nonhuman primate models in HIV vaccine development.
Academic Article Fundamental difference in the content of high-mannose carbohydrate in the HIV-1 and HIV-2 lineages.
Academic Article Use of cloned SIVmac of defined sequence for the study of AIDS pathogenesis. SIV vaccine studies in rhesus monkeys
Academic Article Public health. A sound rationale needed for phase III HIV-1 vaccine trials.
Academic Article Nonhuman primate lentiviruses: models for human infection.
Academic Article Experimental infection of rhesus monkeys with type D retrovirus.
Academic Article The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys.
Academic Article Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes.
Academic Article Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys.
Academic Article Seroprevalence of HIV-1 and HIV-2 in Guinea Bissau in 1980.
Academic Article Long-term persistent infection of macaque monkeys with the simian immunodeficiency virus.
Academic Article Animal models for acquired immunodeficiency syndrome.
Academic Article SIV vaccine studies in rhesus monkeys
Academic Article Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses.
Academic Article Immunopathogenesis of SIVmac.
Academic Article Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus
Academic Article Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes.
Academic Article Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239.
Academic Article Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system.
Academic Article Direct relationship between suppression of virus-specific immunity and emergence of cytomegalovirus disease in simian AIDS.
Academic Article Live attenuated HIV vaccines: a proposal for further research and development.
Academic Article Studies on the specificity of the vaccine effect elicited by inactivated simian immunodeficiency virus
Academic Article Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys.
Academic Article AIDS vaccine development.
Academic Article Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene.
Academic Article Effects of natural sequence variation on recognition by monoclonal antibodies neutralize simian immunodeficiency virus infectivity.
Academic Article Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus.
Academic Article Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.
Academic Article The evolution of virus diseases: their emergence, epidemicity, and control.
Academic Article Will there be a live-attenuated HIV vaccine available for human safety trials by the year 2000? Interview by Gordon Nary.
Academic Article Use of simian immunodeficiency virus for evaluation of AIDS vaccine strategies.
Academic Article Lymphoproliferative syndrome in an immunodeficient rhesus monkey naturally infected with an HTLV-III-like virus (STLV-III).
Academic Article Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome.
Academic Article Sequence variability of simian immunodeficiency virus in a persistently infected rhesus monkey.
Academic Article Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication.
Academic Article Importance of B-cell responses for immunological control of variant strains of simian immunodeficiency virus.
Academic Article MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques.
Academic Article Feasibility of developing live attenuated HIV vaccines: conclusions and recommendations
Academic Article Safety issues facing development of a live-attenuated, multiply deleted HIV-1 vaccine.
Academic Article Diversity of envelope genes from an uncloned stock of SIVmac251.
Academic Article Simian immunodeficiency virus from the sooty mangabey and rhesus macaque is modified with O-linked carbohydrate.
Academic Article Effect of simian immunodeficiency virus infection on tumor necrosis factor-alpha production by alveolar macrophages.
Academic Article Inching towards a vaccine for AIDS.
Academic Article Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239.
Academic Article Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection.
Academic Article Viral determinants of neurological disease in AIDS
Academic Article AIDS-like disease in macaque monkeys induced by simian immunodeficiency virus: a vaccine trial
Academic Article Simian Retrovirus
Academic Article Infection of baboons with human immunodeficiency virus-2 (HIV-2)
Academic Article Simian immunodeficiency viruses.
Academic Article Origin of the human AIDS virus.
Academic Article Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Academic Article Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III.
Academic Article Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes.
Academic Article ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
Academic Article Neutralizing capacity of monoclonal antibodies that recognize peptide sequences underlying the carbohydrates on gp41 of simian immunodeficiency virus.
Academic Article Evidence against extracellular exposure of a highly immunogenic region in the C-terminal domain of the simian immunodeficiency virus gp41 transmembrane protein.
Academic Article Humoral immune responses to T cell tropic retrovirus simian T lymphotropic virus type III in monkeys with experimentally induced acquired immune deficiency-like syndrome.
Academic Article Titration and characterization of two rhesus-derived SIVmac challenge stocks.
Academic Article Macrophage-tropic variants of SIV are associated with specific AIDS-related lesions but are not essential for the development of AIDS.
Academic Article International collaboration comparing neutralization and binding assays for monoclonal anataibodies to simian immunodeficiency virus
Academic Article Functional contributions of carbohydrate on AIDS virus glycoprotein.
Academic Article Molecular Comparisons of the D-Type Retrovirus. Chapter 27
Academic Article Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys.
Academic Article SIVmac expressing hybrid envelope proteins containing HIV-1 V3 and/or C4 sequences is not competent for replication.
Academic Article Relative importance and functional role of genetic elements targeted for a live attenuated AIDS vaccine.
Academic Article Nonhuman primate models for human letivirus infection and their use in vaccine research
Academic Article Use of simian immunodeficiency virus for AIDS vaccine research
Academic Article HIV with multiple gene deletions as a live attenuated vaccine for AIDS.
Academic Article Simian models for AIDS.
Academic Article The simian immunodeficiency viruses.
Academic Article Lymphadenopathy in macaques experimentally infected with the simian immunodeficiency virus (SIV).
Academic Article A radical strategy for development of a vaccine against HIV-1
Academic Article Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.
Academic Article Non-human primate models for AIDS vaccines.
Academic Article Approaches to AIDS research.
Academic Article Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus.
Academic Article Differences in neutralization of simian lentivirus (SIVMAC) in lymphocyte and macrophage cultures.
Academic Article Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment.
Academic Article HIV vaccine design: insights from live attenuated SIV vaccines.
Academic Article Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III.
Academic Article Use of simian immunodeficiency viruses for AIDS research.
Academic Article Vaccine protection against simian immunodeficiency virus in monkeys using recombinant gamma-2 herpesvirus.
Academic Article Problems and issues facing development of a preventive vaccine for AIDS: lessons from Pasteur
Academic Article Infection of a yellow baboon with simian immunodeficiency virus from African green monkeys: evidence for cross-species transmission in the wild.
Academic Article Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239.
Concept AIDS Vaccines
Concept Simian Acquired Immunodeficiency Syndrome
Concept Acquired Immunodeficiency Syndrome
Concept AIDS-Related Complex
Academic Article Influence of mismatch of Env sequences on vaccine protection by live attenuated simian immunodeficiency virus.
Academic Article SIV vpx is essential for macrophage infection but not for development of AIDS.
Academic Article Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques.
Academic Article Localization of productively infected cells in the spleen and Peyer's patches of rhesus macaques during acute infection with SIVmac239?nef-enhanced green fluorescent protein.
Academic Article AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.
Academic Article AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity.
Academic Article Host Anti-antibody Responses Following Adeno-associated Virus-mediated Delivery of Antibodies Against HIV and SIV in Rhesus Monkeys.
Grant CONFERENCE OF AIDS PATHOGENESIS
Grant TYPE D RETROVIRUSES AND MACAQUE IMMUNODEFICIENCY
Grant 19th Annual Symposium-Nonhuman Primate Models for AIDS
Grant UMASS Center for AIDS Research (CFAR)
Grant Molecular Basis for SIV Pathogenicity
Grant New England Primate Research Center Base Grant
Grant Gamma-2 Herpesviruses as Vaccine Vectors for AIDS
Grant Mechanisms of protective immunity induced by live attenuated SIV vaccines
Grant HERPESVIRUSES AS VACCINE VECTORS FOR AIDS
Grant Gamma-2 Herpesviruses as Vaccine Vectors for AIDS
Grant Herpesviruses as Vaccine Vectors for AIDS
Grant LIVE ATTENUATED MULTIPLY DELETED HIV1 VACCINE FOR AIDS
Grant Consortium for AIDS Vaccine Research in Nonhuman Primates
Grant LIVE ATTENUATED MULTIPLY DELETED HIV-1 VACCINE FOR AIDS
Grant Gamma-2 Herpesviruses as Vaccine Vectors for AIDS
Academic Article Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates.
Academic Article Persistent Low-Level Replication of SIV?nef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
Academic Article Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque.
Academic Article Protection against HIV Acquisition in the RV144 Trial.
Academic Article Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.
Academic Article Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.
Academic Article Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in Acute Viremia in Simian Immunodeficiency Virus ?nef-Infected Animals.
Academic Article The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques.
Academic Article Vaccine protection against SIVmac239 acquisition.
Academic Article Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
Academic Article Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV.
Academic Article Enhanced enzyme kinetics of reverse transcriptase variants cloned from animals infected with SIVmac239 lacking viral protein X.
Academic Article Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome.
Search Criteria
  • Acquired Immunodeficiency Syndrome
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.