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One or more keywords matched the following items that are connected to Toker, Alex
Item TypeName
Academic Article Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors.
Academic Article Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils.
Academic Article A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.
Academic Article The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate.
Academic Article The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.
Academic Article Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling.
Academic Article Signalling through the lipid products of phosphoinositide-3-OH kinase.
Academic Article Determination of the specific substrate sequence motifs of protein kinase C isozymes.
Academic Article NF-kappaB signaling--an alternate pathway for oxidative stress responses.
Academic Article A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D.
Academic Article Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase.
Academic Article mTOR and Akt signaling in cancer: SGK cycles in.
Academic Article Akt/protein kinase b and glycogen synthase kinase-3beta signaling pathway regulates cell migration through the NFAT1 transcription factor.
Academic Article 3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling.
Academic Article Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species.
Academic Article p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex.
Academic Article Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB.
Academic Article Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association.
Academic Article Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site.
Academic Article Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation.
Academic Article Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.
Academic Article Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.
Academic Article Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation.
Academic Article The biology and biochemistry of diacylglycerol signalling. Meeting on molecular advances in diacylglycerol signalling.
Academic Article Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells.
Academic Article Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion.
Academic Article Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells.
Academic Article PDGF initiates two distinct phases of protein kinase C activity that make unequal contributions to the G0 to S transition.
Academic Article Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway.
Academic Article Genetic manipulation of protein kinase C in vivo.
Academic Article Lacrimal gland PKC isoforms are differentially involved in agonist-induced protein secretion.
Academic Article Signaling through protein kinase C.
Academic Article Regulation of novel protein kinase C epsilon by phosphorylation.
Academic Article Phosphoinositide 3-kinases-a historical perspective.
Academic Article Effect of overexpression of constitutively active PKCalpha on rat lacrimal gland protein secretion.
Academic Article A rapid method for determining protein kinase phosphorylation specificity.
Academic Article PDK-1 and protein kinase C phosphorylation.
Academic Article PKD controls avß3 integrin recycling and tumor cell invasive migration through its substrate Rabaptin-5.
Academic Article 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Academic Article Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter.
Academic Article Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex.
Academic Article Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase.
Academic Article Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin.
Academic Article The carboxyl terminus of protein kinase c provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1.
Academic Article Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation.
Academic Article Acetylation-dependent regulation of Skp2 function.
Academic Article PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.
Academic Article Protein kinases as mediators of phosphoinositide 3-kinase signaling.
Academic Article Effect of overexpression of protein kinase C alpha on rat lacrimal gland protein secretion.
Academic Article Identifying protein kinase C substrates: an introduction.
Academic Article Using phospho-motif antibodies to determine kinase substrates.
Concept 1-Phosphatidylinositol 4-Kinase
Concept Protein Kinase C-alpha
Concept Casein Kinase I
Concept Phosphatidylinositol 3-Kinase
Concept Cyclin-Dependent Kinase 2
Concept Protein Kinase Inhibitors
Concept Glycogen Synthase Kinase 3
Concept Cyclin-Dependent Kinase 6
Concept Casein Kinase II
Concept Protein Kinase C-delta
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Cyclin-Dependent Kinase 4
Concept MAP Kinase Signaling System
Concept Protein Kinase C
Concept Protein Kinase C-epsilon
Concept S-Phase Kinase-Associated Proteins
Academic Article Targeting Akt3 signaling in triple-negative breast cancer.
Academic Article Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Academic Article Signalling specificity in the Akt pathway in breast cancer.
Academic Article The phosphoinositide 3-kinase pathway and therapy resistance in cancer.
Academic Article PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
Academic Article Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Academic Article pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
Grant Identifying lincRNAs that Mediate PI 3 Kinase Dependent Breast Cancer
Grant Novel regulation of PI3K/Akt to direct targeted breast cancer therapies
Grant The Akt and NFAT Pathway and the Regulaton of Cancer Cell Motility
Grant Regulation and function of the PKC/PKD signaling pathway
Academic Article Cross-talk between the CK2 and AKT signaling pathways in cancer.
Academic Article Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.
Academic Article Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.
Academic Article PI 3-Kinase Signaling: AKTing up inside the Cell.
Academic Article AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.
Academic Article Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling.
Academic Article Lactate Lights up PI3K Inhibitor Resistance in Breast Cancer.
Grant Discovery, Regulation and Function of the PI 3-Kinase and AKT Pathway in Cancer
Search Criteria
  • Elongation Factor 2 Kinase
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.