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One or more keywords matched the following items that are connected to Demetri, George
Item TypeName
Academic Article Soft tissue sarcomas of adults: state of the translational science.
Academic Article Management of soft-tissue sarcomas: an overview and update.
Academic Article Uptake of radiolabeled somatostatin analog is detectable in patients with metastatic foci of sarcoma.
Academic Article Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor.
Academic Article Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma.
Academic Article Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study.
Academic Article Major developments in the understanding and treatment of soft-tissue sarcomas in adults.
Academic Article Adults with Ewing's sarcoma/primitive neuroectodermal tumor: adverse effect of older age and primary extraosseous disease on outcome.
Academic Article ET-743: the US experience in sarcomas of soft tissues.
Academic Article Gemcitabine and vinorelbine combination chemotherapy for patients with advanced soft tissue sarcomas: results of a phase II trial.
Academic Article Clinical management of gastrointestinal stromal tumors: before and after STI-571.
Academic Article NCCN sarcoma practice guidelines. National Comprehensive Cancer Network.
Academic Article Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas.
Academic Article Malignant epithelioid angiomyolipoma ('sarcoma ex angiomyolipoma') of the kidney: a case report and review of the literature.
Academic Article Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors.
Academic Article Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.
Academic Article Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 32-2004. A 68-year-old man with a large retroperitoneal mass.
Academic Article Small molecule tyrosine kinase inhibitor and depression.
Academic Article Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas.
Academic Article A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas.
Academic Article Targeting the molecular pathophysiology of gastrointestinal stromal tumors with imatinib. Mechanisms, successes, and challenges to rational drug development.
Academic Article Phase 2 Southwest Oncology Group-directed intergroup trial (S0505) of sorafenib in advanced soft tissue sarcomas.
Academic Article Two patients with sarcoma. Case 2. Uterine sarcoma.
Academic Article Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma.
Academic Article Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: associations with clinical characteristics, pathophysiological variables and toxicity.
Academic Article Soft tissue sarcoma.
Academic Article Update on new diagnostic and therapeutic approaches for sarcomas.
Academic Article Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948).
Academic Article mTOR inhibitors in sarcoma.
Academic Article Diagnosis in oncology. Askin tumor.
Academic Article Management of malignant gastrointestinal stromal tumours.
Academic Article NCCN: Sarcoma.
Academic Article Detection of circulating tumor cells in patients with Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
Academic Article Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk.
Academic Article Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
Academic Article Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.
Academic Article Soft tissue sarcoma.
Academic Article Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.
Academic Article Soft tissue sarcoma clinical practice guidelines in oncology.
Academic Article High-dose ifosfamide in the treatment of sarcomas of soft tissues and bone.
Academic Article Disease state awareness in sarcoma.
Academic Article Markers of angiogenesis and clinical features in patients with sarcoma.
Academic Article Synovial sarcoma: prognostic significance of tumor size, margin of resection, and mitotic activity for survival.
Academic Article Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma.
Academic Article First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study.
Academic Article Results of single-agent and combination chemotherapy for advanced soft tissue sarcomas. Implications for decision making in the clinic.
Academic Article Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma.
Academic Article Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy.
Academic Article Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors: results of a multicenter phase 2 trial.
Academic Article Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy.
Academic Article Crossover randomized comparison of intravenous versus intravenous/oral mesna in soft tissue sarcoma treated with high-dose ifosfamide.
Concept Sarcoma, Small Cell
Concept Sarcoma, Clear Cell
Concept Sarcoma, Synovial
Concept Sarcoma
Concept Sarcoma, Alveolar Soft Part
Academic Article Results of an international randomized phase III trial of the mammalian target of rapamycin inhibitor ridaforolimus versus placebo to control metastatic sarcomas in patients after benefit from prior chemotherapy.
Academic Article Clinical outcomes and safety with trabectedin therapy in patients with advanced soft tissue sarcomas following failure of prior chemotherapy: results of a worldwide expanded access program study.
Academic Article Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: a retrospective pooled analysis of five phase II trials.
Academic Article A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas.
Academic Article International expert opinion on patient-tailored management of soft tissue sarcomas.
Academic Article Dystrophin is a tumor suppressor in human cancers with myogenic programs.
Academic Article How to decide whether to offer and use "nonstandard" therapies in patients with advanced sarcomas and gastrointestinal stromal tumors: global variations in clinical practice, assessment, and access to therapies in diseases with limited incidence and data.
Academic Article c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas.
Academic Article Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy.
Academic Article Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib.
Academic Article Ombrabulin plus cisplatin versus placebo plus cisplatin in patients with advanced soft-tissue sarcomas after failure of anthracycline and ifosfamide chemotherapy: a randomised, double-blind, placebo-controlled, phase 3 trial.
Academic Article Phase 1 study of oral abexinostat, a histone deacetylase inhibitor, in combination with doxorubicin in patients with metastatic sarcoma.
Academic Article A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemotherapy treatments.
Academic Article Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma Vaccines.
Academic Article Whole Lung Irradiation in Adults with Metastatic Ewing Sarcoma: Practice Patterns and Implications for Treatment.
Academic Article Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma.
Academic Article Updated results of a phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas.
Academic Article Advances and controversies in the management of soft tissue sarcomas.
Academic Article Dose effect of imatinib (IM) in patients (pts) with metastatic GIST - Phase III Sarcoma Group Study S0033.
Academic Article Results of the phase III, placebo-controlled trial (SUCCEED) evaluating the mTOR inhibitor ridaforolimus (R) as maintenance therapy in advanced sarcoma patients (pts) following clinical benefit from prior standard cytotoxic chemotherapy (CT).
Academic Article Phase II study of gemcitabine/vinorelbine (GV) as first or second line chemotherapy in patients with metastatic soft tissue sarcoma (STS).
Academic Article High rates of histopathologic discordance in sarcoma with implications for clinical care.
Academic Article Randomized, open-label, multicenter, phase III study of eribulin versus dacarbazine in patients (pts) with leiomyosarcoma (LMS) and adipocytic sarcoma (ADI).
Academic Article Early metabolic response to continuous daily dosing of sunitinib in soft tissue sarcomas (STS) other than GIST using FDG- PET.
Academic Article A randomized phase 2 study of the thrombospondin-mimetic peptide ABT-510 in patients with advanced soft tissue sarcoma (STS).
Academic Article Soft tissue sarcoma (STS): Challenges in identification, treatment patterns, and costs of disease management in the U.S.
Academic Article Inhibition of heat shock protein 90 (Hsp90) with the novel agent IPI-504 in metastatic GIST following failure of tyrosine kinase inhibitors (TKIs) or other sarcomas: Clinical results from phase I trial.
Academic Article Phase II intergroup study of sorafenib (S) in advanced soft tissue sarcomas (STS): SWOG 0505.
Academic Article Continuous daily dosing (CDD) of sunitinib (SU) in patients with metastatic soft tissue sarcomas (STS) other than GIST: Results of a phase II trial.
Academic Article Early response evaluation of therapy with AP23573 (an mTOR inhibitor) in sarcoma using [18F]2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) scan.
Academic Article SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Academic Article Efficacy and tolerability of trabectedin in elderly patients with sarcoma: subgroup analysis from a phase III, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma.
Academic Article Evolution of the International Sarcoma Community: A Personal Perspective.
Academic Article Safety and efficacy of Pazopanib in advanced soft tissue sarcoma: PALETTE (EORTC 62072) subgroup analyses.
Academic Article Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma.
Academic Article Guillain-Barre syndrome observed with adoptive transfer of lymphocytes genetically engineered with an NY-ESO-1 reactive T-cell receptor.
Academic Article A phase II multi-strata study of lurbinectedin as a single agent or in combination with conventional chemotherapy in metastatic and/or unresectable sarcomas.
Academic Article Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy.
Academic Article Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1.
Academic Article LRRC15 Targeting in Soft-Tissue Sarcomas: Biological and Clinical Implications.
Academic Article The current reality of soft tissue sarcomas: advances, controversies, areas for improvement, and promising new treatments.
Academic Article Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network.
Academic Article Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study.
Academic Article Real-world outcomes of patients with locally advanced or metastatic epithelioid sarcoma.
Academic Article First-in-Human Phase I Study of ABBV-085, an Antibody-Drug Conjugate Targeting LRRC15, in Sarcomas and Other Advanced Solid Tumors.
Academic Article Real-World Evidence and Advanced Soft Tissue Sarcoma: An Unbreakable Bond (ESMO Sarcoma and GIST Symposium 2020 Industry Satellite Symposium, Milan, February 4, 2020).
Academic Article Contributions of Real-World Evidence and Real-World Data to Decision-Making in the Management of Soft Tissue Sarcomas.
Academic Article Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities.
Academic Article Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer.
Search Criteria
  • Sarcoma
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.