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MAP Kinase Kinase Kinase 5
Biophysical and structural characterization of the thioredoxin-binding domain of protein kinase ASK1 and its interaction with reduced thioredoxin.
Cysteine residues mediate high-affinity binding of thioredoxin to ASK1.
The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress.
MAP Kinase Kinase Kinase 2