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One or more keywords matched the following items that are connected to Kaufman, Howard
Item TypeName
Academic Article Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): a trial of the Eastern Cooperative Oncology Group.
Academic Article A new mouse model for evaluating the immunotherapy of human colorectal cancer.
Academic Article Defining the critical hurdles in cancer immunotherapy.
Concept Ileal Neoplasms
Concept Colonic Neoplasms
Concept Mouth Neoplasms
Concept Breast Neoplasms
Concept Stomach Neoplasms
Concept Bone Neoplasms
Concept Head and Neck Neoplasms
Concept Bile Duct Neoplasms
Concept Immunotherapy, Active
Concept Neoplasms, Experimental
Concept Immunotherapy, Adoptive
Concept Colorectal Neoplasms
Concept Cancer Vaccines
Concept Pancreatic Neoplasms
Concept Gallbladder Neoplasms
Concept Ovarian Neoplasms
Concept Kidney Neoplasms
Concept Neoplasms, Multiple Primary
Concept Immunotherapy
Concept Brain Neoplasms
Concept Lung Neoplasms
Concept Rectal Neoplasms
Concept Gastrointestinal Neoplasms
Concept Skin Neoplasms
Concept Splenic Neoplasms
Concept Peritoneal Neoplasms
Concept Neoplasms
Concept Thyroid Neoplasms
Concept Early Detection of Cancer
Concept Uterine Cervical Neoplasms
Concept Liver Neoplasms
Concept Facial Neoplasms
Concept Endometrial Neoplasms
Concept Prostatic Neoplasms
Concept Adrenal Gland Neoplasms
Concept Uveal Neoplasms
Concept Urinary Bladder Neoplasms
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".
Academic Article The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma.
Academic Article Implementation of an Interleukin-2 National Registry: an opportunity to improve cancer outcomes.
Academic Article The Use of Registries to Improve Cancer Treatment: A National Database for Patients Treated with Interleukin-2 (IL-2).
Academic Article Insertion of interleukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity.
Academic Article Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders.
Academic Article Cancer immunotherapy trials: leading a paradigm shift in drug development.
Academic Article NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade.
Academic Article A retrospective analysis of High-Dose Interleukin-2 (HD IL-2) following Ipilimumab in metastatic melanoma.
Academic Article First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients.
Academic Article Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Academic Article Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial.
Academic Article Discovery and clinical introduction of first-in-class imipridone ONC201.
Academic Article Contemporary experience with high-dose interleukin-2 therapy and impact on survival in patients with metastatic melanoma and metastatic renal cell carcinoma.
Academic Article Clinical development of talimogene laherparepvec (T-VEC): a modified herpes simplex virus type-1-derived oncolytic immunotherapy.
Academic Article Impact of Sequencing Targeted Therapies With High-dose Interleukin-2 Immunotherapy: An Analysis of Outcome and Survival of Patients With Metastatic Renal Cell Carcinoma From an On-going Observational IL-2 Clinical Trial: PROCLAIMSM.
Academic Article Consensus nomenclature for CD8+ T cell phenotypes in cancer.
Academic Article Combination immunotherapy: a road map.
Academic Article Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.
Academic Article Improved survival and tumor control with Interleukin-2 is associated with the development of immune-related adverse events: data from the PROCLAIMSM registry.
Academic Article Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after =1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial.
Academic Article Integrating oncolytic viruses in combination cancer immunotherapy.
Academic Article An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0.
Academic Article Author Correction: Integrating oncolytic viruses in combination cancer immunotherapy.
Academic Article Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma.
Academic Article Oncolytic virus therapy for cancer.
Academic Article Current approaches to novel therapeutics in pancreatic cancer.
Academic Article Immunotherapy for Merkel cell carcinoma: a turning point in patient care.
Academic Article Efficacy and Safety of First-line Avelumab Treatment in Patients With Stage IV Metastatic Merkel Cell Carcinoma: A Preplanned Interim Analysis of a Clinical Trial.
Academic Article Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses.
Academic Article Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer.
Academic Article Talimogene Laherparepvec (T-VEC) and Other Oncolytic Viruses for the Treatment of Melanoma.
Academic Article Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines.
Academic Article Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma.
Academic Article Local delivery of poxvirus vaccines for melanoma.
Academic Article Cytokine therapy for cancer.
Academic Article Panniculitis after vaccination against CEA and MUC1 in a patient with pancreatic cancer.
Academic Article Precision immunology: the promise of immunotherapy for the treatment of cancer.
Academic Article Herpes simplex virus oncolytic vaccine therapy in melanoma.
Academic Article Is tumor immunity the same thing as autoimmunity? Implications for cancer immunotherapy.
Academic Article Imaging the immune response to monitor tumor immunotherapy.
Academic Article Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study.
Academic Article Vaccines for melanoma and renal cell carcinoma.
Academic Article A phase I trial of intra lesional RV-B7.1 vaccine in the treatment of malignant melanoma.
Academic Article Into the clinic: Talimogene laherparepvec (T-VEC), a first-in-class intratumoral oncolytic viral therapy.
Academic Article TroVax(®) vaccine therapy for renal cell carcinoma.
Academic Article TroVax, a recombinant modified vaccinia Ankara virus encoding 5T4: lessons learned and future development.
Academic Article Immunogenicity and safety of a recombinant vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate.
Academic Article A Phase II Study of AT-101 to Overcome Bcl-2--Mediated Resistance to Androgen Deprivation Therapy in Patients With Newly Diagnosed Castration-Sensitive Metastatic Prostate Cancer.
Academic Article Optimal management of metastatic melanoma: current strategies and future directions.
Academic Article Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma.
Academic Article 4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines.
Academic Article Finding gold in tumour immunotherapy.
Academic Article Poxviruses as vectors for cancer immunotherapy.
Academic Article Management of metastatic melanoma to the breast with high-dose interleukin-2 and surgical resection.
Academic Article Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.
Academic Article First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors.
Academic Article Quantitative Analysis of Immune Infiltrates in Primary Melanoma.
Academic Article Low-dose interleukin-2 impairs host anti-tumor immunity and inhibits therapeutic responses in a mouse model of melanoma.
Academic Article Immune oncology, immune responsiveness and the theory of everything.
Academic Article Chemokines in tumor immunotherapy.
Academic Article Oncolytic viruses: focusing on the tumor microenvironment.
Academic Article Management of metastatic malignant melanoma of the bladder.
Academic Article Host lymphodepletion enhances the therapeutic activity of an oncolytic vaccinia virus expressing 4-1BB ligand.
Academic Article Viral vaccines for cancer immunotherapy.
Academic Article Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies.
Academic Article Detection of cancer in patients by reduced lymphocytic cortisol metabolism-enhancing effect.
Academic Article Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression.
Academic Article Management of Metastatic Melanoma in 2018.
Academic Article Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer.
Academic Article Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma.
Academic Article Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma.
Academic Article Clinical protocol. Intra-Lesional rF-B7.1 versus rF-TRICOM vaccine in the treatment of metastatic cancer.
Academic Article Enterocutaneous fistula in cancer patients: etiology, management, outcome, and impact on further treatment.
Academic Article Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
Academic Article Results of a phase I trial of a recombinant vaccinia virus that expresses carcinoembryonic antigen in patients with advanced colorectal cancer.
Academic Article Local delivery of recombinant vaccinia virus expressing secondary lymphoid chemokine (SLC) results in a CD4 T-cell dependent antitumor response.
Academic Article An association between corticosteroid use and melanoma recurrence: a case report and review of the literature.
Academic Article Antitumor activity and immune responses induced by a recombinant carcinoembryonic antigen-vaccinia virus vaccine.
Academic Article Integrating bench with bedside: the role of vaccine therapy in the treatment of solid tumors.
Academic Article Oncolytic virus immunotherapy for melanoma.
Academic Article Specific immunotherapy using a recombinant vaccinia virus expressing human carcinoembryonic antigen.
Academic Article Combination chemotherapy and ALVAC-CEA/B7.1 vaccine in patients with metastatic colorectal cancer.
Academic Article Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study.
Academic Article Innovations and strategies for the development of anticancer vaccines.
Academic Article Recursive SVM biomarker selection for early detection of breast cancer in peripheral blood.
Academic Article Single-incision laparoscopic surgery for intra-abdominal metastatic melanoma.
Academic Article Chemokines and cancer.
Academic Article Characteristics of patients diagnosed with both melanoma and renal cell cancer.
Academic Article Adenocarcinoma in an isolated ileal sleeve 30 years after periureteral wrap.
Academic Article HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice.
Academic Article Gene therapy for antitumor vaccination.
Academic Article Interleukin-10 enhances the therapeutic effectiveness of a recombinant poxvirus-based vaccine in an experimental murine tumor model.
Academic Article The next generation of vaccines for the treatment of cancer.
Academic Article Intratumoral Approaches for the Treatment of Melanoma.
Academic Article Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma.
Academic Article The tumour microenvironment and implications for cancer immunotherapy.
Academic Article The role of poxviruses in tumor immunotherapy.
Academic Article Unleashing the therapeutic potential of oncolytic viruses.
Academic Article Serum vascular endothelial growth factor and fibronectin predict clinical response to high-dose interleukin-2 therapy.
Academic Article Vaccines for colorectal cancer and renal cell carcinoma.
Academic Article Immune properties of recombinant vaccinia virus encoding CD154 (CD40L) are determined by expression of virally encoded CD40L and the presence of CD40L protein in viral particles.
Academic Article Optimizing prostate cancer treatment by combining local radiation therapy with systemic vaccination.
Academic Article Clinical Management of Multiple Melanoma Brain Metastases: A Systematic Review.
Academic Article Innovative treatments for pancreatic cancer.
Academic Article Development of the PANVAC-VF vaccine for pancreatic cancer.
Academic Article Immunotherapy for pancreatic cancer: current concepts.
Academic Article Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma.
Academic Article Clinical and safety profile of high-dose interleukin-2 treatment in elderly patients with metastatic melanoma and renal cell carcinoma.
Academic Article Adjuvant therapy for malignant melanoma.
Academic Article The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma.
Academic Article Carcinoembryonic antigen (CEA) presentation and specific T cell-priming by human dendritic cells transfected with CEA-mRNA.
Academic Article High-dose interleukin-2 (IL-2) for the treatment of melanoma: safety considerations and future directions.
Academic Article Local delivery of vaccinia virus expressing multiple costimulatory molecules for the treatment of established tumors.
Academic Article Targeting costimulatory pathways for tumor immunotherapy.
Academic Article Intrarectal vaccination with recombinant vaccinia virus expressing carcinoembronic antigen induces mucosal and systemic immunity and prevents progression of colorectal cancer.
Academic Article Evaluation of classical clinical endpoints as surrogates for overall survival in patients treated with immune checkpoint blockers: a systematic review and meta-analysis.
Academic Article Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma.
Academic Article Rational Combination Immunotherapy: Understand the Biology.
Academic Article Leiomyoma of the breast.
Academic Article Patterns of Clinical Response with Talimogene Laherparepvec (T-VEC) in Patients with Melanoma Treated in the OPTiM Phase III Clinical Trial.
Academic Article Treatment of pediatric ocular melanoma with high-dose interleukin-2 and thalidomide.
Academic Article Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy).
Academic Article The contralateral sentinel node.
Academic Article gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma.
Academic Article Oncolytic viruses: a new class of immunotherapy drugs.
Academic Article Pox viral vaccine approaches.
Academic Article TG-4010 Transgene.
Academic Article Surgical Management of Melanoma.
Academic Article Chronic granulomatous dermatitis induced by talimogene laherparepvec therapy of melanoma metastases.
Academic Article Immune system versus tumor: shifting the balance in favor of DCs and effective immunity.
Academic Article Molecular Pathways: Mechanism of Action for Talimogene Laherparepvec, a New Oncolytic Virus Immunotherapy.
Academic Article Gene therapy with poxvirus vectors.
Academic Article Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.
Academic Article Prostate-specific antigen vaccines for prostate cancer.
Academic Article The prognostic significance of stable disease following high-dose interleukin-2 (IL-2) treatment in patients with metastatic melanoma and renal cell carcinoma.
Academic Article Current issues in cancer vaccine development.
Academic Article Combination Immunotherapy for Melanoma.
Academic Article Metastasectomy following incomplete response to high-dose interleukin-2.
Academic Article MVA-5T4-induced immune responses are an early marker of efficacy in renal cancer patients.
Academic Article Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy.
Academic Article Interleukin-2, Ipilimumab, and Anti-PD-1: Clinical Management and the Evolving Role of Immunotherapy for the Treatment of Patients With Metastatic Melanoma.
Academic Article Durable response rate as an endpoint in cancer immunotherapy: insights from oncolytic virus clinical trials.
Academic Article Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule.
Academic Article Local IL-21 promotes the therapeutic activity of effector T cells by decreasing regulatory T cells within the tumor microenvironment.
Academic Article Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
Academic Article A recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA).
Academic Article Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer.
Academic Article A therapeutic cancer vaccine targeting carcinoembryonic antigen in intestinal carcinomas.
Academic Article A phase I trial of intralesional rV-Tricom vaccine in the treatment of malignant melanoma.
Academic Article A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer.
Academic Article Surgical treatment of stage IV melanoma.
Academic Article Immunotherapy for melanoma.
Academic Article Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma.
Academic Article Clinical applications of p53-directed gene therapy.
Academic Article Cutaneous head and neck melanoma in OPTiM, a randomized phase 3 trial of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor for the treatment of unresected stage IIIB/IIIC/IV melanoma.
Academic Article CEA-based vaccines.
Academic Article Poxvirus vaccines for cancer and HIV therapy.
Academic Article Biomarkers for Immunotherapy: Current Developments and Challenges.
Academic Article An update on TroVax for the treatment of progressive castration-resistant prostate cancer.
Academic Article Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule.
Academic Article IFN-? cancer immunotherapy: new kid on the block.
Academic Article Avelumab: is it time to get excited?
Academic Article Next generation approaches for tumor vaccination.
Academic Article Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery.
Academic Article Strategies for cancer therapy using carcinoembryonic antigen vaccines.
Academic Article Living with Merkel Cell Carcinoma (MCC): Development of a Conceptual Model of MCC Based on Patient Experiences.
Academic Article Low-dose interleukin-2 administered pre-operatively to patients with gastric cancer activates peripheral and peritumoral lymphocytes but does not affect prognosis.
Academic Article Increased carcinoembryonic antigen expression in cervical intraepithelial neoplasia grade 3 and in cervical squamous cell carcinoma.
Academic Article Talimogene laherparepvec (T-VEC) as cancer immunotherapy.
Academic Article Manipulating the local tumor microenvironment with poxviruses expressing costimulatory molecules.
Grant ENHANCING TUMOR VACCINES WITH CO-STIMULATORY MOLECULES
Grant ANTIGEN PRESENTATION BY CEA DIRECTED TUMOR VACCINES
Grant CANARYPOX VACCINE EXPRESSIONG CEA AND B7
Academic Article Avelumab Immunotherapy: Management of Adverse Events Associated With New Treatment for Merkel Cell Carcinoma.
Academic Article Two roads for oncolytic immunotherapy development.
Academic Article MEK inhibition enhances oncolytic virus immunotherapy through increased tumor cell killing and T cell activation.
Academic Article Triple threat to cancer: rationale for combining oncolytic viruses, MEK inhibitors, and immune checkpoint blockade.
Academic Article Oncolytic viruses: a new class of immunotherapy drugs.
Academic Article Overall survival by clinical risk category for high dose interleukin-2 (HD IL-2) treated patients with metastatic renal cell cancer (mRCC): data from the PROCLAIMSM registry.
Academic Article The promise of Immuno-oncology: implications for defining the value of cancer treatment.
Academic Article Oncolytic Immunotherapy.
Academic Article Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.
Academic Article Multi-parametric flow cytometry staining procedure for analyzing tumor-infiltrating immune cells following oncolytic herpes simplex virus immunotherapy in intracranial glioblastoma.
Academic Article Oncolytic virus immunotherapy induces immunogenic cell death and overcomes STING deficiency in melanoma.
Academic Article Final analyses of OPTiM: a randomized phase III trial of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor in unresectable stage III-IV melanoma.
Academic Article Effect of tumor removal on the presence of lymphocytic cortisol metabolism-enhancing factor in plasma of cancer patients.
Academic Article Cancer patients' plasma lacking lymphocytic cortisol metabolism-enhancing factor in comparison with plasma of healthy donors.
Academic Article Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.
Academic Article Initial clinical response predicts outcome and is associated with dose schedule in metastatic melanoma and renal cell carcinoma patients treated with high-dose interleukin 2.
Academic Article Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1.
Academic Article High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014.
Academic Article Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.
Academic Article Defining current gaps in quality measures for cancer immunotherapy: consensus report from the Society for Immunotherapy of Cancer (SITC) 2019 Quality Summit.
Academic Article Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Academic Article Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19.
Academic Article Clinical landscape of oncolytic virus research in 2020.
Mentoring - Current Student Opportunity Oncolytic Virus Therapy for Cancer
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.