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Mrinmoy Das, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Displaying 25 of 35 total Publications Show all
  1. Leyva-Castillo JM, Das M, Strakosha M, McGurk A, Artru E, Kam C, Alasharee M, Wesemann DR, Tomura M, Karasuyama H, Brombacher F, Geha RS. IL-4 acts on skin-derived dendritic cells to promote the TH2 response to cutaneous sensitization and the development of allergic skin inflammation. J Allergy Clin Immunol. 2024 Dec; 154(6):1462-1471.e3. PMID: 38996877; PMCID: PMC11625010.
    Citations: 2
    Fields: AllAllergy and ImmunologyTranslation:HumansAnimalsCells
  2. Das M, Mukherjee S, Geha RS. Phosphodiesterase 4 Inhibitors, Basophils, and Atopic Dermatitis. J Invest Dermatol. 2024 May; 144(5):924-926. PMID: 38441508.
    Citations:
    Fields: DerDermatologyTranslation:HumansAnimalsCells
  3. Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, Lotfy S, El Marsafy A, Ezzelarab M, Farrar M, Schmidt BAR, NandyMazumdar M, Guttman-Yassky E, Sheets A, Vidic KM, Murphy G, Schlievert PM, Chou J, Leyva-Castillo JM, Janssen E, Timilshina M, Geha RS. Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency. J Allergy Clin Immunol. 2024 Jul; 154(1):143-156. PMID: 38185418.
    Citations: 1
    Fields: AllAllergy and ImmunologyTranslation:HumansAnimalsCells
  4. Wilkie H, Timilshina M, Rahmayanti S, Das M, Pelovitz T, Geha RS. DOCK8 is essential for neutrophil mediated clearance of cutaneous S. aureus infection. Clin Immunol. 2023 09; 254:109681. PMID: 37385324; PMCID: PMC10529992.
    Citations:
    Fields: AllAllergy and ImmunologyTranslation:AnimalsCells
  5. Yang B, Wilkie H, Das M, Timilshina M, Bainter W, Woods B, Daya M, Boorgula MP, Mathias RA, Lai P, Petty CR, Weller E, Harb H, Chatila TA, Leung DYM, Beck LA, Simpson EL, Hata TR, Barnes KC, Phipatanakul W, Leyva-Castillo JM, Geha RS. The IL-4Ra Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice. J Allergy Clin Immunol. 2023 05; 151(5):1296-1306.e7. PMID: 36690254; PMCID: PMC10164706.
    Citations: 6
    Fields: AllAllergy and ImmunologyTranslation:AnimalsCells
  6. Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI Insight. 2021 11 08; 6(21). PMID: 34747366; PMCID: PMC8663570.
    Citations: 14
    Fields: MedMedicine (General)Translation:HumansAnimalsCells
  7. Bainter W, Lougaris V, Wallace JG, Badran Y, Hoyos-Bachiloglu R, Peters Z, Wilkie H, Das M, Janssen E, Beano A, Farhat KB, Kam C, Bercich L, Incardona P, Villanacci V, Bondioni MP, Meini A, Baronio M, Abarzua P, Parolini S, Tabellini G, Maio S, Schmidt B, Goldsmith JD, Murphy G, Hollander G, Plebani A, Chou J, Geha RS. Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor ??B kinase alpha (IKKa). Sci Immunol. 2021 Sep 17; 6(63):eabf6723. PMID: 34533979; PMCID: PMC8930078.
    Citations: 8
    Fields: AllAllergy and ImmunologyTranslation:HumansAnimalsCells
  8. Das M, Leyva-Castillo JM, Geha RS. Basophil: The cell that itches. J Allergy Clin Immunol. 2021 09; 148(3):708-709. PMID: 34147536.
    Citations:
    Fields: AllAllergy and ImmunologyTranslation:HumansCells
  9. Leyva-Castillo JM, Das M, Artru E, Yoon J, Galand C, Geha RS. Mast cell-derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the TH1 cell response to cutaneous antigen exposure. J Allergy Clin Immunol. 2021 06; 147(6):2305-2315.e3. PMID: 33316284; PMCID: PMC8184568.
    Citations: 21
    Fields: AllAllergy and ImmunologyTranslation:HumansAnimalsCells
  10. Stephen-Victor E, Das M, Karnam A, Pitard B, Gautier JF, Bayry J. Potential of regulatory T-cell-based therapies in the management of severe COVID-19. Eur Respir J. 2020 09; 56(3). PMID: 32616599.
    Citations: 68
    Fields: PulPulmonary MedicineTranslation:HumansCellsPHPublic Health
  11. Janssen E, Tohme M, Butts J, Giguere S, Sage PT, Velázquez FE, Kam C, Milin E, Das M, Sobh A, Al-Tamemi S, Luscinskas FW, Batista F, Geha RS. DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers. JCI Insight. 2020 08 06; 5(15). PMID: 32573493; PMCID: PMC7455063.
    Citations: 9
    Fields: MedMedicine (General)Translation:HumansAnimalsCells
  12. Das M, Stephen-Victor E, Bayry J. Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms. Oncoimmunology. 2020 06 05; 9(1):1773193. PMID: 32923130; PMCID: PMC7458635.
    Citations: 4
    Fields: AllAllergy and ImmunologyNeoNeoplasmsTranslation:HumansCells
  13. Karnam A, Rambabu N, Das M, Bou-Jaoudeh M, Delignat S, Käsermann F, Lacroix-Desmazes S, Kaveri SV, Bayry J. Therapeutic normal IgG intravenous immunoglobulin activates Wnt-ß-catenin pathway in dendritic cells. Commun Biol. 2020 03 04; 3(1):96. PMID: 32132640.
    Citations: 8
    Translation:HumansAnimalsCells
  14. Das M, Karnam A, Stephen-Victor E, Gilardin L, Bhatt B, Kumar Sharma V, Rambabu N, Patil V, Lecerf M, Käsermann F, Bruneval P, Narayanaswamy Balaji K, Benveniste O, Kaveri SV, Bayry J. Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy. Cell Death Dis. 2020 01 23; 11(1):50. PMID: 31974400; PMCID: PMC6978335.
    Citations: 26
    Fields: CelCell BiologyIntInternal MedicineTranslation:HumansCells
  15. Galeotti C, Karnam A, Das M, Kaveri SV, Bayry J. Acid Stripping of Surface IgE Antibodies Bound to FceRI is Unsuitable for the Functional Assays that Require Long-Term Culture of Basophils and Entire Removal of Surface IgE. Int J Mol Sci. 2020 Jan 13; 21(2). PMID: 31941161.
    Citations: 3
    Fields: BioBiochemistryCheChemistryMolMolecular BiologyTranslation:HumansCells
  16. Saha C, Das M, Stephen-Victor E, Friboulet A, Bayry J, Kaveri SV. Correction: Saha, C., et al. Differential Effects of Viscum album Preparations on the Maturation and Activation of Human Dendritic Cells and CD4+ T Cell Responses. Molecules 2016, 21, 912. Molecules. 2019 Oct 18; 24(20). PMID: 31635421; PMCID: PMC6832133.
    Citations:
    Fields: BioBiology
  17. Mukherjee S, Karnam A, Das M, Babu SPS, Bayry J. Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4. Commun Biol. 2019; 2:169. PMID: 31098402; PMCID: PMC6505026.
    Citations: 13
    Translation:HumansAnimalsCells
  18. Ray S, Da Costa R, Das M, Nandi D. Interplay of cold shock protein E with an uncharacterized protein, YciF, lowers porin expression and enhances bile resistance in Salmonella Typhimurium. J Biol Chem. 2019 06 07; 294(23):9084-9099. PMID: 30992363; PMCID: PMC6556570.
    Citations: 12
    Fields: BioBiochemistryTranslation:Cells
  19. Karnam A, Stephen-Victor E, Das M, Magy L, Vallat JM, Bolgert F, Simon-Loriere E, Kaveri SV, Sakuntabhai A, Bayry J. Does intravenous immunoglobulin therapy in Guillain-Barré syndrome patients interfere with serological Zika detection? Autoimmun Rev. 2019 06; 18(6):632-633. PMID: 30959213.
    Citations: 1
    Fields: AllAllergy and Immunology
  20. Das M, Alzaid F, Bayry J. Regulatory T Cells under the Mercy of Mitochondria. Cell Metab. 2019 02 05; 29(2):243-245. PMID: 30726757.
    Citations: 8
    Fields: CelCell BiologyMetMetabolismTranslation:HumansCells
  21. Galeotti C, Stephen-Victor E, Karnam A, Das M, Gilardin L, Maddur MS, Wymann S, Vonarburg C, Chevailler A, Dimitrov JD, Benveniste O, Bruhns P, Kaveri SV, Bayry J. Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE. J Allergy Clin Immunol. 2019 08; 144(2):524-535.e8. PMID: 30529242.
    Citations: 25
    Fields: AllAllergy and ImmunologyTranslation:HumansAnimalsCells
  22. Sharma M, Das M, Stephen-Victor E, Galeotti C, Karnam A, Maddur MS, Bruneval P, Kaveri SV, Bayry J. Regulatory T cells induce activation rather than suppression of human basophils. Sci Immunol. 2018 05 25; 3(23). PMID: 29802207.
    Citations: 24
    Fields: AllAllergy and ImmunologyTranslation:HumansCells
  23. Stephen-Victor E, Karnam A, Fontaine T, Beauvais A, Das M, Hegde P, Prakhar P, Holla S, Balaji KN, Kaveri SV, Latgé JP, Aimanianda V, Bayry J. Aspergillus fumigatus Cell Wall a-(1,3)-Glucan Stimulates Regulatory T-Cell Polarization by Inducing PD-L1 Expression on Human Dendritic Cells. J Infect Dis. 2017 12 05; 216(10):1281-1294. PMID: 28968869.
    Citations: 39
    Fields: ComCommunicable DiseasesTranslation:HumansAnimalsCells
  24. Maddur MS, Stephen-Victor E, Das M, Prakhar P, Sharma VK, Singh V, Rabin M, Trinath J, Balaji KN, Bolgert F, Vallat JM, Magy L, Kaveri SV, Bayry J. Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy. J Neuroinflammation. 2017 03 20; 14(1):58. PMID: 28320438; PMCID: PMC5360043.
    Citations: 8
    Fields: NeuNeurologyTranslation:HumansCells
  25. Saha C, Das M, Patil V, Stephen-Victor E, Sharma M, Wymann S, Jordi M, Vonarburg C, Kaveri SV, Bayry J. Monomeric Immunoglobulin A from Plasma Inhibits Human Th17 Responses In Vitro Independent of FcaRI and DC-SIGN. Front Immunol. 2017; 8:275. PMID: 28352269.
    Citations: 15
    Fields: AllAllergy and Immunology
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.